Rchr
J-GLOBAL ID：201801013634474369   Update date: Feb. 16, 2024

Yabuki Yasushi

ヤブキ ヤスシ | Yabuki Yasushi
Affiliation and department：
Kumamoto University Institute of Molecular Embryology and Genetics

About Kumamoto University Institute of Molecular Embryology and Genetics


Homepage URL  (1)： http://www.imeg.kumamoto-u.ac.jp/bunya_top/genomic_neurology/staff/
Research field  (3)： Neuroscience - general ,  Pharmaceuticals - health and biochemistry ,  Pharmacology
Research keywords  (12)： Neuronal plasticity ,  Psychiatric disorder ,  Neurodegenerative disease ,  グアニン四重鎖 ,  核酸高次構造 ,  α-synuclein ,  プリオン性タンパク質 ,  T-type voltage gated calcium channel ,  learning and memory ,  高次脳機能 ,  Fatty acid binding protein ,  Calcum/calmodulin-dependent protein kinase II
Research theme for competitive and other funds  (22)：
  • 2023 - 2026 Supramolecular behavior and dynamic capture of meta-aggregates
  • 2023 - 2026 【アミロイドと核酸高次構造】RNA相転移によるメタアグリゲート形成と伝播
  • 2023 - 2025 ストレス脆弱性を規定する分子基盤の解明
  • 2021 - 2025 RNA相転移によるプリオン性タンパク質のプロテオスタシス破綻機構
  • 2021 - 2024 RNAグアニン四重鎖によるα-シヌクレイン凝集・伝播調節機構の解明
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Papers (51)：
  • Susumu Ikenoshita, Kazuya Matsuo, Yasushi Yabuki, Kosuke Kawakubo, Sefan Asamitsu, Karin Hori, Shingo Usuki, Yuki Hirose, Toshikazu Bando, Kimi Araki, et al. A cyclic pyrrole-imidazole polyamide reduces pathogenic RNA in CAG/CTG triplet repeat neurological disease models. The Journal of clinical investigation. 2023
  • Kenta Kudo, Karin Hori, Sefan Asamitsu, Kohei Maeda, Yukari Aida, Mei Hokimoto, Kazuya Matsuo, Yasushi Yabuki, Norifumi Shioda. Structural polymorphism of the nucleic acids in pentanucleotide repeats associated with CANVAS. 2023
  • Kazuya Matsuo, Sefan Asamitsu, Kohei Maeda, Kosuke Kawakubo, Ginji Komiya, Kenta Kudo, Yusuke Sakai, Karin Hori, Susumu Ikenoshita, Shingo Usuki, et al. RNA G-quadruplexes forming scaffolds for alpha-synuclein aggregation lead to progressive neurodegeneration. bioRxiv. 2023
  • Sefan Asamitsu, Yasushi Yabuki, Kazuya Matsuo, Moe Kawasaki, Yuki Hirose, Gengo Kashiwazaki, Anandhakumar Chandran, Toshikazu Bando, Dan Ohtan Wang, Hiroshi Sugiyama, et al. RNA G-quadruplex organizes stress granule assembly through DNAPTP6 in neurons. Science advances. 2023. 9. 8. eade2035
  • Qingyun Guo, Ichiro Kawahata, Wenbin Jia, Haoyang Wang, An Cheng, Yasushi Yabuki, Norifumi Shioda, Kohji Fukunaga. α-Synuclein decoy peptide protects mice against α-synuclein-induced memory loss. CNS neuroscience & therapeutics. 2023. 29. 6. 1547-1560
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MISC (30)：
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Education (3)：
  • 2012 - 2015 Tohoku University Graduate School of Pharmaceutical Sciences Division of Bio-Pharmaceutical Science
  • 2010 - 2012 Tohoku University Graduate School of Pharmaceutical Sciences Division of Bio-Pharmaceutical Science
  • 2006 - 2010 Tohoku University Faculty of Pharmaceutical Sciences Department of Pharmaceutical Sciences
Professional career (1)：
  • 博士 (薬科学) (東北大学)
Work history (5)：
  • 2023/12 - 現在 Kumamoto University Institute of Molecular Embryology and Genetics Associate Professor
  • 2019/10 - 2023/11 Kumamoto University Institute of Molecular Embryology and Genetics Assistant Professor
  • 2015/04 - 2019/09 Tohoku University Graduate School of Pharmaceutical Sciences Assistant professor
  • 2018/04 - 2019/04 University of Calgary Cumming School of Medicine JSPS Overseas Research Fellowships
  • 2014/04 - 2015/03 Tohoku University Graduate School of Pharmaceutical Sciences Research Fellowship for Young Scientists in Japan Society for the Promotion of Science
Awards (15)：
  • 2019/12 - 日本薬学会東北支部奨励賞
  • 2019/10 - Excellent Research Award for AsCNP2019
  • 2019/07 - 東北大学大学院薬学研究科長賞
  • 2017/12 - 東北大学大学院薬学研究科長賞
  • 2017/09 - 日本神経化学会奨励賞
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Association Membership(s) (8)：
The International Society for Neurochemistry ,  Society of Neuroscience ,  The Japanese Society of Cerebral Blood Flow and Metabolism. ,  JAPAN SOCIETY FOR DEMENTIA RESEARCH ,  THE PHARMACEUTICAL SOCIETY OF JAPAN ,  THE JAPAN NEUROSCIENCE SOCIETY ,  THE JAPANESE SOCIETY FOR NEUROCHEMISTRY ,  THE JAPANESE PHARMACOLOGICAL SOCIETY
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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