Research keywords (6)：
Cell biology
, Musculoskeletal immunology
, Osteoporosis treatment
, Biomechanical analysis
, Orthopaedic surgery
, Spine surgery
Research theme for competitive and other funds (11)：
2023 - 2027 Molecular Mechanisms of Age-Related Skin Diseases Triggered by Age-Related Alterations in the Local Endocrine System of the Skin
2023 - 2025 A global perspective on orthopaedic surgery: utilizing bone quality metrics to predict postoperative complications
2022 - 2025 Visualizing for Surgical Risk in the Elderly: Optimize the Surgical Procedures Based on a Prediction Model of Post-operative Complications
2021 - 2024 Comprehensive analysis of dropped head syndrome
2019 - 2022 An Effect Comparison of Osteoporosis Treatment on Spinal Instrumentation
2020 - 2021 Cell Therapy for Successful Bone Fusion using Stem Cells from Human Exfoliated Deciduous Teeth
2019 - 2020 Analysis of Osteoporosis Treatment Discontinuation during Spinal Fixation
2019 - Effect of Denosumab on Bone Fusion in the Mice Posterolateral Spinal Fusion Model
2019 - Development of Treatments for Spinal Fusion Surgery using Stem Cells from Human Exfoliated Deciduous Teeth
2017 - 2019 Evaluation of Novel Surrogate Marker for Hypocalcemia Following Denosumab Treatment in Patients with Metastasis
2018 - Management of Osteoporosis Treatment during Spinal Surgery
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Papers (52)：
Tony M. Keaveny, Mary Oates, Donald Betah, Yifei Shi, Jen Timoshanko, David C. Lee, Mohamad Bydon, Kelly Krohn, Koji Ishikawa. Effects of romosozumab on bone strength around a pedicle screw as evaluated by biomechanical computed tomography-based virtual stress tests in postmenopausal women. The Spine Journal. 2025
Koji Ishikawa, Soji Tani, Nobuhiro Sakai, Yoshifumi Kudo, Hideyo Horiuchi, Hiromi Kimura-Suda, Masamichi Takami, Mayumi Tsuji, Katsunori Inagaki, Yuji Kiuchi, et al. Mouse model of anti-RANKL discontinuation reveals reduced bone mass and quality through disruption of bone remodeling. Bone Research. 2025
Soji Tani, Koji Ishikawa, Erika Chiapparelli, Gaston Camino-Willhuber, Lukas Schönnagel, Thomas Caffard, Krizia Amoroso, Ali E. Guven, Jennifer Shue, Benjamin A. Alman, et al. Impact of Lumbar Degenerative Changes on Vertebral Bone Strength: A Finite Element Analysis. Journal of Orthopaedic Research. 2025
Makoto Nakagawa, Eijiro Shimada, Nicholas Guardino, Ryo Miyamoto, Vijitha Puviindran, Emily Peairs, Ariana Matarangas, Koji Ishikawa, Tuyet Nguyen, Makenna Browne, et al. Protein Phosphatase 1 Regulatory Subunit 3C integrates cholesterol metabolism and isocitrate dehydrogenase in chondrocytes and neoplasia. Proceedings of the National Academy of Sciences of the United States of America. 2025. 122. 16. e2501519122
Koki Tsuchiya, Yusuke Oshita, Haruka Emori, Soji Tani, Takashi Nagai, Austin Ennis, Mahoko Ishikawa, Yoshifumi Kudo, Benjamin Alman, Koji Ishikawa. Bone turnover markers as predictors of hypocalcemia in patients with bone metastases receiving denosumab. JBMR Plus. 2025
Exploring Mechanisms of Anti-RANKL Treatment Discontinuation
(The 12th Seoul Symposium on Bone Health & The 36th Spring Scientific Congress of the Korean Society for Bone and Mineral Research (SSBH 2024) 2024)
Building Better Bones for Long-Term Outcomes: Strategies for Osteoporosis Management in Hip Surgery
(2024 International Congress of the Korean Hip Society The 68th Annual Meeting(ICKHS 2024) 2024)
Provide forums for discussion with distinguished experts and develop next generation leaders of bone and musculoskeletal research through scientific communication
(Japan Bone Academy 2021 Virtual Meeting(English lecture) 2021)
Current concepts of perioperative management for patients with osteoporosis: How do osteoporosis medications affect
(2021 International Joint Meeting of KSNS and WSCS 2021)
2021/09 - 現在 Research Associate Senior, Department of Orthopaedic Surgery, Duke University School of Medicine
2020/10 - 現在 Senior Assistant Professor, Department of Orthopaedic Surgery, Showa University School of Medicine
2018/10 - 2020/09 Assistant Professor, Department of Orthopaedic Surgery, Showa University School of Medicine
2017/04 - 2018/10 Spine Fellow, Sanraku Hospital, Spine and Spinal Cord Center
2016/04 - 2017/03 Assistant Professor, Department of Orthopaedic Surgery, Showa University School of Medicine
- 2010/03 M.D., Showa University School of Medicine
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Committee career (3)：
2020/02 - 現在 apan Osteoporosis Society Bone Turnover Marker Investigation Committee
2020/01 - 現在 Young Surgeons Committee of SICOT
2019/08 - 現在 Councilor of Society of Minimally Invasive Spinal Treatment
Awards (16)：
2025/05 - LSRS OrthoCarolina Fellowship Young Investigator Grant
2024/10 - The ASBMR Hartmut H. Malluche Early Career Investigator Award
2023/10 - Young Investigator Award of the American Society for Bone and Mineral Research
2021 - Outstanding Researcher Award of the 41st Annual Meeting of Japanese Society for Bone Morphometry
2020 - Distinguished Paper Award of the 22nd Annual Meeting of Japan Osteoporosis Society
2019 - JASA(Japan Association of Spine surgeons with Ambition) Best Discusser Award
2019 - AOSpine Asia Pacific Fellowship Award
2018 - Japan Osteoporosis Society, Young Scientist Award
2018 - Excellent Paper Award of 46th of Annual Meeting of Japanese Society for Spine Surgery and
2017 - Medical Research Award of Showa University Medical Association
2016 - Alumni Association Award of Department of Orthopaedic Surgery, Showa University School of Medicine
2016 - Young Investigator Research Award of the Japanese Society for Bone Morphometry
2015 - Young Investigator Travel Grant of the American Society for Bone Mineral Research
2015 - Young Investigator Research Award of the Japanese Society for Bone Morphometry
2014 - Young Investigator Travel Grant of the American Society for Bone Mineral Research
2014 - Young Investigator Research Award of the Japanese Society for Bone Morphometry
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Association Membership(s) (12)：
THE KANTO SOCIETY OF ORTHOPEDICS AND TRAUMATOLOGY
, 日本低侵襲脊椎外科学会
, 日本脊椎・脊髄神経手術手技学会
, 日本成人脊柱変形学会
, 日本脊椎インストゥルメンテーション学会
, 日本腰痛学会
, JAPANESE SOCIETY FOR BONE MORPHOMETRY
, ASBMR
, AO-Spine
, THE JAPANESE SOCIETY FOR OSTEOPOROSIS
, THE JAPANESE SOCIETY FOR SPINE SURGERY AND RELATED RESEARCH
, THE JAPANESE ORTHOPAEDIC ASSOCIATION
