Nozomi Asaoka

アサオカノゾミ | Nozomi Asaoka

Affiliation and department：

Research field (3)： Neuropathology , Neuroscience - general , Pharmacology

Research keywords (5)：意思決定 , 強迫性障害 , 行動薬理学 , 電気生理学 , 神経薬理学

Research theme for competitive and other funds (8)：

2024 - 2027 データ駆動型解析により導出した強迫症治療候補薬の臨床実証と適応拡大に向けた研究開発
2022 - 2025 タスク経験の記憶固定化に着目した仕事中毒の神経基盤の解析
2021 - 2023 有害事象の時系列解析と実証実験による創薬標的の導出
2020 - 2023 神経発達障害に起因する精神疾患の機序解明と新規治療基盤の確立
2020 - 2023 Drug target finding based on the analysis of real world data

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Papers (23)：

Hideo Hagihara, Hirotaka Shoji, Satoko Hattori, Giovanni Sala, Yoshihiro Takamiya, Mika Tanaka, Masafumi Ihara, Mihiro Shibutani, Izuho Hatada, Kei Hori, et al. Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment. eLife. 2024. 12
Hikari Hatakama, Nozomi Asaoka, Kazuki Nagayasu, Hisashi Shirakawa, Shuji Kaneko. Amelioration of obsessive-compulsive disorder by intracellular acidification of cortical neurons with a proton pump inhibitor. Translational psychiatry. 2024. 14. 1. 27-27
Ellen Tedford, Norhidayah Binti Badya, Conor Laing, Nozomi Asaoka, Shuji Kaneko, Beatrice Maria Filippi, Glenn Alan McConkey. Infection-induced extracellular vesicles evoke neuronal transcriptional and epigenetic changes. Scientific reports. 2023. 13. 1. 6913-6913
Hikari Hatakama, Nozomi Asaoka, Kazuki Nagayasu, Hisashi Shirakawa, Shuji Kaneko. A selective serotonin reuptake inhibitor ameliorates obsessive-compulsive disorder-like perseverative behavior by attenuating 5-HT2C receptor signaling in the orbitofrontal cortex. Neuropharmacology. 2022. 206. 108926-108926
Koki Nagaoka, Nozomi Asaoka, Kazuki Nagayasu, Hisashi Shirakawa, Shuji Kaneko. Enhancement of adenosine A2A signaling improves dopamine D2 receptor antagonist-induced dyskinesia via β-arrestin signaling. Frontiers in neuroscience. 2022. 16. 1082375-1082375

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Lectures and oral presentations (27)：

Distinct roles of synaptic plasticity in the prefrontal cortex in habit formation and execution
(NEURO2024 2024)
Region-specific plastic changes in the prefrontal cortex drive compulsive task performance
(35th World Congress Collegium Internationale Neuro-Psychopharmacologicum 2024)
Region- and circuit-specific synaptic plasticity in the prefrontal cortex determine the individuality in habit execution
(第97回日本薬理学会年会・第44回日本臨床薬理学会学術総会 2023)
Region-specific cortical plasticity during habit formation determines individuality
(生理研研究会記憶研究会2023 2023)
Region-specific cortical plasticity during habit formation determines individuality in habit strength
(第46回日本神経科学大会 2023)

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Education (2)：

2015 - 2018 Kyoto University
2009 - 2015 Kyoto University

Professional career (1)：

博士(薬学) (京都大学大学院)

Work history (3)：

2021/08 - 現在 Graduate School of Medicine, Kyoto University Pharmacology
2021/04 - 2021/07 Graduate School of Medicine, Kyoto University Pharmacology
2018/04 - 2021/03 Kyoto Prefectural University of Medicine Pharmacology Assistant Professor

Awards (7)：

2024/05 - 日本神経精神薬理学会鍋島賞 Region-specific plastic changes in the prefrontal cortex drive compulsive task performance
2024/05 - 日本神経精神薬理学会 JSNP Excellent Presentation Award for CINP Region-specific plastic changes in the prefrontal cortex drive compulsive task performance
2022/06 - 第2回国際シンポジウムマルチスケール脳/MCCS-Asia Poster Award Region- and proficiency-specific synaptic potentiation in the prefrontal cortex during learning of normal and compulsive operant behavior
2022/01 - 日本薬学会関西支部日本薬学会関西支部奨励賞
2021/03 - 第94回日本薬理学会年会優秀発表賞

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Association Membership(s) (4)：

THE JAPAN NEUROSCIENCE SOCIETY , THE JAPANESE SOCIETY OF NEUROPSYCHOPHARMACOLOGY , THE PHARMACEUTICAL SOCIETY OF JAPAN , THE JAPANESE PHARMACOLOGICAL SOCIETY

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