Rchr
J-GLOBAL ID:201801014603802887
Update date: Oct. 06, 2020
Tohnai Genki
トウナイ ゲンキ | Tohnai Genki
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Affiliation and department:
名古屋大学 大学院医学系研究科
About 名古屋大学 大学院医学系研究科
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Detailed information
Job title:
特任助教
Research field (1):
Neurology
Research theme for competitive and other funds (3):
2019 - 2022 異常タンパク分解系を標的とした運動ニューロン疾患治療薬の開発
2017 - 2019 Expression and role of autophagy-related molecules in motor neuron disease
2015 - 2017 Development of a novel therapy for neurodegenerative disease using tacrolimus derivative
Papers (17):
Ryoichi Nakamura, Kazuharu Misawa, Genki Tohnai, Masahiro Nakatochi, Sho Furuhashi, Naoki Atsuta, Naoki Hayashi, Daichi Yokoi, Hazuki Watanabe, Hirohisa Watanabe, et al. A multi-ethnic meta-analysis identifies novel genes, including ACSL5, associated with amyotrophic lateral sclerosis. Communications biology. 2020. 3. 1. 526-526
Ryoichi Nakamura, Genki Tohnai, Naoki Atsuta, Masahiro Nakatochi, Naoki Hayashi, Hazuki Watanabe, Daichi Yokoi, Hirohisa Watanabe, Masahisa Katsuno, Yuishin Izumi, et al. Genetic and functional analysis of KIF5A variants in Japanese patients with sporadic amyotrophic lateral sclerosis. Neurobiology of aging. 2020
Madoka Iida, Kentaro Sahashi, Naohide Kondo, Hideaki Nakatsuji, Genki Tohnai, Yutaka Tsutsumi, Seiya Noda, Ayuka Murakami, Kazunari Onodera, Yohei Okada, et al. Src inhibition attenuates polyglutamine-mediated neuromuscular degeneration in spinal and bulbar muscular atrophy. Nature communications. 2019. 10. 1. 4262-4262
Kondo N, Tohnai G, Sahashi K, Iida M, Kataoka M, Nakatsuji H, Tsutsumi Y, Hashizume A, Adachi H, Koike H, et al. DNA methylation inhibitor attenuates polyglutamine-induced neurodegeneration by regulating Hes5. EMBO molecular medicine. 2019. 11. 5
Genki Tohnai, Ryoichi Nakamura, Jun Sone, Masahiro Nakatochi, Daichi Yokoi, Masahisa Katsuno, Hazuki Watanabe, Hirohisa Watanabe, Mizuki Ito, Yuanzhe Li, et al. Frequency and characteristics of the TBK1 gene variants in Japanese patients with sporadic amyotrophic lateral sclerosis. Neurobiology of aging. 2018. 64. 158.e15-158.e19-158.e19
more...
MISC (2):
熱田 直樹, 中村 亮一, 林 直毅, 藤内 玄規, 勝野 雅央, 祖父江 元. 【ALS 2019】ALSにおける患者レジストリの役割 JaCALSなど. BRAIN and NERVE: 神経研究の進歩. 2019. 71. 11. 1215-1225
中村 亮一, 曽根 淳, 熱田 直樹, 藤内 玄規, 横井 大知, 中杤 昌弘, 渡辺 宏久, 伊藤 瑞規, 勝野 雅央, 和泉 唯信, et al. 孤発性筋萎縮性側索硬化症患者における発症年齢と遺伝学的背景に関する検討. 臨床神経学. 2016. 56. Suppl. S414-S414
Professional career (1):
医学博士 (名古屋大学)
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