Research keywords (4)：
ミトコンドリア
, 活性酸素
, Cell
, Radiation
Research theme for competitive and other funds (13)：
2022 - 2025 Is signal from mitochondria involved in radiation-induced inflammation?
2021 - 2024 放射線障害に関わる遅発性活性酸素と核外シグナルの機構解明
2019 - 2023 Suppression of delayed ROS rescue normal human fibroblasts after radiation exposure.
2018 - 2021 遅発性活性酸素を抑制するがん細胞特異的因子は放射線治療の標的となりうるか
2017 - 2020 Study of clinically radio-resistance factors using clinical radiation-resistant oral cancer cells
2014 - 2017 遅発性活性酸素が関与する放射線抵抗性獲得機構の解明
2013 - 2016 Development of instruction packages for new radiation education associated with the community
2012 - 2015 Biological analysis of the relationship between FDG uptake and p53 status
2012 - 2014 分泌性因子がもたらすミトコンドリア機能変化と放射線抵抗性獲得機構の解明
2009 - 2010 がんの微小環境因子が放射線感受性に影響を及ぼす機構に関する研究
2008 - 2010 Analyzing and exploiting the characteristics of intratumor quiescent cells in search of the potential as a cancer stem cell
2008 - 2010 Characterization and biological assessment of DNA-Protein crosslink repair in vertebrate cells
2007 - 2008 バイスタンダー効果の抵抗性因子を標的とした殺腫瘍細胞効果の増強に関する研究
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Papers (89)：
玉利 勇樹, 菓子野 元郎, 鈴木 実. IL-6/mTOR/STAT3経路による細胞内酸化抑制を介したヒト膵臓がん由来細胞株における放射線耐性獲得への関与(IL-6/mTOR/STAT3 pathway is involved in the acquisition of radiation resistance in human pancreatic cancer-derived cell line by suppressing cellular oxidation). 日本放射線影響学会大会講演要旨集. 2023. 66回. 97-97
Genro Kashino, Shinko Kobashigawa. Induction of the reactive oxygen species in cells after irradiation. Radiation Biology Research Communications. 2023. 58. 3. 238-249
Naonori Hu, Minoru Suzuki, Shin-ichiro Masunaga, Genro Kashino, Yuko Kinashi, Yi-Wen Chen, Yong Liu, Koki Uehara, Toshinori Mitsumoto, Hiroki Tanaka, et al. Experimentally determined relative biological effectiveness of cyclotron-based epithermal neutrons designed for clinical BNCT: in vitro study. Journal of Radiation Research. 2023. 64. 5. 811-815
Tsubasa Watanabe, Tomohiro Yoshikawa, Hiroki Tanaka, Yuko Kinashi, Genro Kashino, Shin-Ichiro Masunaga, Toshimitsu Hayashi, Koki Uehara, Koji Ono, Minoru Suzuki. Pharmacokinetic Study of 14C-Radiolabeled p-Boronophenylalanine (BPA) in Sorbitol Solution and the Treatment Outcome of BPA-Based Boron Neutron Capture Therapy on a Tumor-Bearing Mouse Model. European journal of drug metabolism and pharmacokinetics. 2023. 48. 4. 443-453
Genro Kashino, Shinko Kobashigawa, Aoki Uchikoshi, Yuki Tamari. VEGF affects mitochondrial ROS generation in glioma cells and acts as a radioresistance factor. Radiation and Environmental Biophysics. 2023. 62. 2. 213-220
2017/04 - 現在 Nara Medical University Associate Professor
2011/01 - 2017/03 Oita University associate professor
2006/04 - 2010/12 Kyoto University Assistant Professor
2003/04 - 2006/04 Nagasaki University
2005/05 - 2005/10 英国グレイ癌研究所(客員研究員)
2003/05 - 2004/03 Gray Cancer Institute
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Awards (1)：
2010/10 - 日本放射線影響学会 奨励賞
Association Membership(s) (5)：
JAPANESE SOCIETY FOR RADIATION ONCOLOGY
, JAPAN RADIOISOTOPE ASSOCIATION
, JAPANESE SOCIETY OF RADIATION SAFETY MANAGEMENT
, THE JAPANESE CANCER ASSOCIATION
, THE JAPANESE RADIATION RESEARCH SOCIETY
