Hasan Arif Ul

Affiliation and department：
Job title： Lecturer

Research field (6)： Cardiology , Nephrology , Tumor diagnostics and therapeutics , Neurology , Cardiology , Systems genomics

Research keywords (7)： Epigenetics , Kidney injury , Cardiomyopathy , Cancer , iPS cell , Metabolic syndrome , Genetics

Research theme for competitive and other funds (6)：

2023 - 2026 The mechanisms for renal protection by klotho protein supplementation
2021 - 2024 腎臓障害をきたすNAD合成系異常におけるエピジェネティクスの役割解明
2020 - 2023 クロト蛋白補充による腎保護についての研究
2017 - 2022 Creating a database of circumstances of ECD (Early Childhood Development) in foreigners' countries of origin and in Japan
2013 - 2016 Effects of Drug Intervention on theRebound of Diet-induced Obesity

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Papers (23)：

Arif Ul Hasan, Satoshi Serada, Sachiko Sato, Mami Obara, Sho Hirata, Yukako Nagase, Yukiko Kondo, Eiichi Taira. KDM4B Histone Demethylase Inhibition Attenuates Tumorigenicity of Malignant Melanoma Cells by Overriding the p53-Mediated Tumor Suppressor Pathway. Journal of Cellular Biochemistry. 2024
Arif Ul Hasan, Mami Obara, Sachiko Sato, Yukiko Kondo, Eiichi Taira. CD146/MCAM links doxorubicin-induced epigenetic dysregulation to the impaired fatty acid transportation in H9c2 cardiomyoblasts. Biochemical and biophysical research communications. 2024. 693. 149370-149370
Tsuneo Takenaka, Arif Hasan, Takeshi Marumo, Tsutomu Inoue, Takashi Miyazaki, Hiromichi Suzuki, Yoshifumi Kurosaki, Naohito Ishii, Akira Nishiyama, Matsuhiko Hayashi. Klotho supplementation reverses renal dysfunction and interstitial fibrosis in remnant kidney. Kidney & blood pressure research. 2023
Hasan Arif, Marumo Takeshi, Obara Mami, Sato Sachilo, Kondo Yukiko, Murase Shiniachi, Taira Eichi. Inhibition of histone demethylation augments NAD synthesis through the Preiss-Handler pathway in cultured human proximal tubular epithelial cell line. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2022. 96. 1-B-P-051
Tsuneo Takenaka, Arif Hasan, Takeshi Marumo, Hiroyuki Kobori, Tsutomu Inoue, Takashi Miyazaki, Hiromichi Suzuki, Akira Nishiyama, Naohito Ishii, Matsuhiko Hayashi. Klotho supplementation attenuates blood pressure and albuminuria in murine model of IgA nephropathy. Journal of hypertension. 2021. 39. 8. 1567-1576

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MISC (22)：

Hasan AU, Miyake K, Murase S, Marumo T. HDAC inhibitors augment de novo NAD synthesis in human proximal epithelial cells. 11th Academic Conference of International University of Health and Welfare University Conference. 2021
Hasan AU, Miyake K, Murase S, Marumo T. A histone deacetylase inhibitor, Sodium 4-Phenyl butyrate inhibits the growth of brain cancer cells by suppressing oncogenic MYC. 10th Academic Conference of International University of Health and Welfare University Conference. 2020
Hasan AU, Rahman A, Kobori H, Miyake K, Nishiyama A, Murase S. (Pro)renin receptor inactivation augments endoplasmic reticulum stress-induced apoptosis in human brain cancer cells. 9th Academic Conference of International University of Health and Welfare University Conference. 2019
Hasan AU, Rahman A, Nishiyama A, Kobori H. Modeling glioblastoma multiforme (GBM) with induced pluripotent stem (iPS) cells to elucidate the role of endoplasmic reticulum (ER) stress on apoptosis, focusing on (pro)renin receptor ((P)RR) modulation. 10th (Pro)Renin receptor forum. 2018
Florescu CM, Hayasaka Y, Babayev T, Oshimi T, Lytnev V, Hasan AU, Martin BJ, Inokawa M, De Haven S. Can we improve TOEFL ITP® scores by teaching test-taking strategies?. 21st JASMEE Academic Meeting. 2018

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Lectures and oral presentations (19)：

Modeling glioblastoma multiforme (GBM) with induced pluripotent stem (iPS) cells to elucidate the role of endoplasmic reticulum (ER) stress on apoptosis, focusing on (pro)renin receptor ((P)RR) modulation
(The 10th (Pro)Renin receptor forum, Tokyo, Japan 2018)
Eicosapentaenoic acid Upregulates VEGF-A through GPR120-mediated and PPARγ-mediated Pathways in Mature Adipocytes
(The 79th Scientific Meeting of the Japanese Circulation Society, Osaka, Japan 2015)
Upregulation of VEGF-A by EPA in 3T3-L1 adipocytes and its mechanisms
(The 10th Chugoku Shikoku CCV Forum, Hiroshima, Japan 2014)
Valsatran suppresses interleukin 6 expression in 3T3-L1 adipocytes
(Renin Angiotensin system Conference, Kagawa, Japan 2012)
Mifepristoneは脂肪組織中のM2マクロファージを増加させる
(Journal of Japan Society for the Study of Obesity 2012)

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Works (1)：

Novel genetic mutations in mosquitoes
Arif Ul Hasan 2000 - 2004

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