Rchr
J-GLOBAL ID:201801014841671502   Update date: Feb. 01, 2024

Honda Ryo

ホンダ リョウ | Honda Ryo
Affiliation and department:
Homepage URL  (1): https://www.gifu-university-ryohonda.com/
Research field  (3): Medical biochemistry ,  Structural biochemistry ,  Tumor diagnostics and therapeutics
Research keywords  (7): protein science ,  ras ,  cancer ,  RT-QUIC ,  amyloid ,  神経変性疾患 ,  構造に基づく創薬
Research theme for competitive and other funds  (7):
  • 2022 - 2025 4リピートタウオパチーの予防・診断を指向したRT-QUIC法の開発と創薬研究
  • 2022 - 2025 Non-G12C変異型RASを標的とするキメラ型タンパク質の開発
  • 2022 - 2024 がん遺伝子産物RASを阻害する細胞膜透過性タンパク質の開発
  • 2020 - 2023 犬の変性性脊髄症を起こす変異SOD1蛋白質の立体構造解析と治療基盤の構築
  • 2019 - 2022 Development of a new anticancer drug using a protein that has high affinity and specifically binds to mutant Ras
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Papers (30):
  • Teiko Komori Nomura, Satoshi Endo, Takuma Kuwano, Kazuya Fukasawa, Shigeo Takashima, Tomoki Todo, Kyoji Furuta, Takuhei Yamamoto, Eiichi Hinoi, Hiroko Koyama, et al. ARL-17477 is a dual inhibitor of NOS1 and the autophagic-lysosomal system that prevents tumor growth in vitro and in vivo. Scientific reports. 2023. 13. 1. 10757-10757
  • Kento Wakayama, Shintaro Kimura, Yui Kobatake, Hiroaki Kamishina, Naohito Nishii, Satoshi Takashima, Ryo Honda, Yuji O Kamatari. Molecular Mechanisms of Aggregation of Canine SOD1 E40K Amyloidogenic Mutant Protein. Molecules (Basel, Switzerland). 2022. 28. 1
  • Tatsushi Nakayama, Ryo Honda, Kazuo Kuwata, Shigeyuki Usui, Bunji Uno. Electrochemical and Mechanistic Study of Superoxide Scavenging by Pyrogallol in N,N-Dimethylformamide through Proton-Coupled Electron Transfer. Electrochem. 2022
  • Tatsushi Nakayama, Ryo Honda, Kazuo Kuwata, Shigeyuki Usui, Bunji Uno. Electrochemical and Mechanistic Study of Reactivities of α-, β-, γ-, and δ-Tocopherol toward Electrogenerated Superoxide in N,N-Dimethylformamide through Proton-Coupled Electron Transfer. Antioxidants. 2021. 11. 1. 9-9
  • Tatsushi Nakayama, Ryo Honda, Kazuo Kuwata, Shigeyuki Usui, Bunji Uno. Electrochemical and Mechanistic Study of Structure-Activity Relationship of α-, β-, γ-, and δ-Tocopherol on Superoxide Elimination in N,N-Dimethylformamide through Proton-Coupled Electron Transfer. 2021
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Patents (2):
  • 異常型タンパク質の検出方法及び神経変性疾患の検査方法
  • 人工タンパク質、Ras阻害剤及び抗がん剤
Professional career (1):
  • 博士(医学) (岐阜大学)
Work history (6):
  • 2023/01 - 現在 One Medicineトランスレーショナルリサーチセンター 兼任
  • 2021/12 - 現在 岐阜大学 大学院連合創薬医療情報研究科 准教授
  • 2017/12 - 2021/11 Gifu University United Graduate School of Drug Discovery and Medical Information Sciences Assistant Professor
  • 2015/04 - 2018/03 Gifu University Graduate School of Medicine PhD
  • 2016/04 - 2017/11 日本学術振興会 特別研究員(DC1)
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