Rchr
J-GLOBAL ID：201801014841949519   Update date: Apr. 02, 2024

Sugiyama Hironori

Sugiyama Hironori
Affiliation and department：
The University of Tokyo The Graduate School of Engineering Department of Applied Chemistry

About The University of Tokyo The Graduate School of Engineering Department of Applied Chemistry


Job title： Research Fellow
Research field  (2)： Cell biology ,  Biophysics
Research keywords  (5)： Cell cycle ,  Live imaging ,  microfluidic device ,  self-reproduction ,  giant vesicle
Research theme for competitive and other funds  (5)：
  • 2022 - 2025 膜局在プローブの汎用的開発手法の実現による胚発生下の内在性Wnt動態の可視化
  • 2021 - 2024 ライブイメージング並列化が拓く細胞質の混み合いと細胞機能を繋ぐ機構の総覧と解明
  • 2021 - 2022 外部形態制御された分裂酵母スフェロプラストを用いた分裂位置決定機構の解明
  • 2018 - 2021 進化可能な化学モデル創出を志向した定常的自己複製ベシクル
  • 2019 - 2020 Quantitative path-investigation of the dynamics of giant vesicles toward the construction of the artificial cell
Papers (10)：
  • Hironori Sugiyama, Yuhei Goto, Yohei Kondo, Damien Coudreuse, Kazuhiro Aoki. Live-cell imaging defines a threshold in CDK activity at the G2/M transition. Developmental Cell. 2024
  • Akinobu Nakamura, Yuhei Goto, Hironori Sugiyama, Shinya Tsukiji, Kazuhiro Aoki. Chemogenetic Manipulation of Endogenous Proteins in Fission Yeast Using a Self-Localizing Ligand-Induced Protein Translocation System. ACS Chemical Biology. 2023. 18. 12. 2506-2515
  • Hironori Sugiyama, Yuhei Goto, Yohei Kondo, Damien Coudreuse, Kazuhiro Aoki. Live-cell imaging provides direct evidence for a threshold in CDK activity at the G2/M transition. 2023
  • Hironori Sugiyama, Toshihisa Osaki, Shoji Takeuchi, Taro Toyota. Role of Negatively Charged Lipids Achieving Rapid Accumulation of Water-Soluble Molecules and Macromolecules into Cell-Sized Liposomes against a Concentration Gradient. Langmuir. 2022
  • Taro Toyota, Hironori Sugiyama, Soichiro Hiroi, Hiroaki Ito, Hiroyuki Kitahata. Chemically artificial rovers based on self-propelled droplets in micrometer-scale environment. Current Opinion in Colloid & Interface Science. 2020. 49. 60-68
ｍore...
MISC (6)：
  • Hironori Sugiyama. Liposomes can accumulate molecules against a concentration gradient without proteins. Viva Origino. 2023. 51. 1. 1-8
  • Hironori SUGIYAMA. Abiotic Molecular Transport against a Concentration Gradient Caused by Flow-induced Asymmetry between the Inner/Outer Leaflets of Cell-sized Liposomes. Seibutsu Butsuri. 2022. 62. 3. 187-189
  • Taro Toyota, Atsufumi Ohtani, Hironori Sugiyama. Molecular Transformation for Self-reproducing Vesicles and Underlying Analysis Methods. Chemical and Pharmaceutical Bulletin. 2021. 69. 10. 947-952
  • 杉山博紀. タンパク質なしにリポソーム内部に特定の物質が濃縮される現象の発見. Bio-Station; https://jugem.hatenadiary.jp/entry/Hydrodynamic_accumulation_200405. 2020
  • Hironori Sugiyama. [Behind the paper] Hydrodynamic accumulation of small molecules and ions into cell-sized liposomes against a concentration gradient. Nature Chemistry Research Community Behind the Paper. 2020
ｍore...
Lectures and oral presentations  (26)：
  • Quantitative Understanding of Cell Cycle Regulation through Live Imaging of CDK Activity
    (Invited Seminar at Academia Sinica 2024)
  • Independent Regulation of CDK-Cyclins Revealed by Theoretical Analysis of Cell Cycle Networks
    (2023)
  • Unveiling CDK Activity Dynamics and Cell Cycle Progression in Fission Yeast Using a FRET Biosensor
    (12th Salk Institute Cell Cycle Meeting 2023 2023)
  • Position of the division plane in externally shape-regulated fission yeast spheroplast
    (2023)
  • The threshold for CDK activity governs G2/M phase transition
    (The 75th Annual Meeting of the Japan Society for Cell Biology 2023)
ｍore...
Education (1)：
  • 2018 - 2021 The University of Tokyo Graduate School of Arts and Sciences Basic Science,Section of Multi-Disciplinary Sciences,
Professional career (1)：
  • Doctor of Philosophy (The University of Tokyo)
Work history (2)：
  • 2021/04 - 現在 Japan Society for the Promotion of Science Research fellow (PD)
  • 2018/04 - 2021/03 Japan Society for the Promotion of Science Research Fellow (DC1)
Awards (7)：
  • 2021/11 - The Biophysical Society of Japan Early Career Award in Biophysics Abiotic molecular transport against a concentration gradient caused by flow-induced asymmetry between the inner/outer leaflets of cell-sized liposomes
  • 2021/03 - The University of Tokyo The Best PhD Dissertation Liposome MANSIONs: quantitative and statistical analysis of the dynamics of cell -sized liposomes under steady flow environment (PhD Dissertation)
  • 2020/09 - The Biophysical Society of Japan Student Presentation Award Automated direct observation unveiled hydrodynamic accumulation of molecules into cell-sized liposomes against a concentration gradient
  • 2019/11 - ANRI The ANRI fellowship
  • 2017/07 - Poster award at Annual meeting of analytical chemistry for young researchers 2017
Show all
Association Membership(s) (7)：
The Molecular Biology Society of Japan ,  Japan Society for Cell Biology ,  Yeast Genetics Society of Japan ,  The Biophysical Society of Japan ,  American Chemical Society ,  The Japan society for Analytical Chemistry ,  The Chemical Society of Japan
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