Rchr
J-GLOBAL ID：201801015387571464
Update date: Oct. 01, 2024
MASUDA Mitsuharu
MASUDA Mitsuharu
Affiliation and department：
Research field (1)：
Molecular biology
Research theme for competitive and other funds (5)：
- 2019 - 2021 Basic research for prevention of arteriosclerosis by cancer preventive ingredients with RB activation ability
- 2018 - 2021 New Cancer Prevention Strategy; Targeting abnormal cancer suppressor genes
- 2015 - 2019 Application of molecular-targeting cancer prevention to human intervention study.
- 2015 - 2017 Elucidation of mechanism of exacerbation by smoking in intervention study for cancer prevention
- 2013 - 2015 Towards realization of molecular-targeting cancer prevention; an attempt to develop safe and effective juice for cancer chemoprevention
Papers (23)：
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Yosuke Ota, Yukihiro Itoh, Yuri Takada, Yasunobu Yamashita, Chenliang Hu, Mano Horinaka, Yoshihiro Sowa, Mitsuharu Masuda, Toshiyuki Sakai, Takayoshi Suzuki. Design, synthesis, and biological evaluation of phenylcyclopropylamine-entinostat conjugates that selectively target cancer cells. Bioorganic & medicinal chemistry. 2024. 100. 117632-117632
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Yukihiro Itoh, Peng Zhan, Toshifumi Tojo, Pattaporn Jaikhan, Yosuke Ota, Miki Suzuki, Ying Li, Zi Hui, Yukiko Moriyama, Yuri Takada, et al. Discovery of Selective Histone Deacetylase 1 and 2 Inhibitors: Screening of a Focused Library Constructed by Click Chemistry, Kinetic Binding Analysis, and Biological Evaluation. Journal of medicinal chemistry. 2023. 66. 22. 15171-15188
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Mitsuharu Masuda, Mano Horinaka, Shusuke Yasuda, Mie Morita, Emi Nishimoto, Hideki Ishikawa, Michihiro Mutoh, Toshiyuki Sakai. Discovery of cancer-preventive juices reactivating RB functions. Environmental health and preventive medicine. 2023. 28. 54-54
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Yosuke Ota, Yukihiro Itoh, Takashi Kurohara, Ritesh Singh, Elghareeb E Elboray, Chenliang Hu, Farzad Zamani, Anirban Mukherjee, Yuri Takada, Yasunobu Yamashita, et al. Cancer-Cell-Selective Targeting by Arylcyclopropylamine-Vorinostat Conjugates. ACS medicinal chemistry letters. 2022. 13. 10. 1568-1573
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Motoki Watanabe, Shogen Boku, Kaito Kobayashi, Yoichi Kurumida, Mamiko Sukeno, Mitsuharu Masuda, Katsura Mizushima, Chikage Kato, Yosuke Iizumi, Kiichi Hirota, et al. A chemoproteoinformatics approach demonstrates that aspirin increases sensitivity to MEK inhibition by directly binding to RPS5. PNAS nexus. 2022. 1. 2. pgac059
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MISC (28)：
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増田 光治, 堀中 真野, 安田 周祐, 森田 美枝, 西幹 栄美, 石川 秀樹, 武藤 倫弘, 酒井 敏行. RB再活性化ジュースの発見(Discovery of RB-reactivating juices). 日本癌学会総会記事. 2023. 82回. 1439-1439
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Itoh, Yukihiro, Zhan, Peng, Tojo, Toshifumi, Jaikhan, Pattaporn, Ota, Yosuke, Suzuki, Miki, Li, Yin, Hui, Zi, Moriyama, Yukiko, Oba, Makoto, et al. Discovery of Selective Histone Deacetylase 1 and 2 Inhibitors: Screening of a Focused Library Constructed by Click Chemistry, Kinetic Binding Analysis, and Biological Evaluation. Journal of Medicinal Chemistry. 2023
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Mitsuharu Masuda, Mano Horinaka, Shusuke Yasuda, Mie Morita, Emi Nishimoto, Hideki Ishikawa, Michihiro Mutoh, Toshiyuki Sakai. Discovery of cancer-preventive juices reactivating RB functions. Environmental Health and Preventive Medicine. 2023. 28. 54-54
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Motoki Watanabe, Shogen Boku, Kaito Kobayashi, Yoichi Kurumida, Mamiko Sukeno, Mitsuharu Masuda, Katsura Mizushima, Chikage Kato, Yosuke Iizumi, Kiichi Hirota, et al. A chemoproteoinformatics approach demonstrates that aspirin increases sensitivity to MEK inhibition by directly binding to RPS5. PNAS Nexus. 2022. 1. 2
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Ota, Yosuke, Itoh, Yukihiro, Kurohara, Takashi, Singh, Ritesh, Elboray, Elghareeb, Hu, Chenliang, Zamani, Farzad, Mukherjee, Anirban, Takada, Yuri, Yamashita, Yasunobu, et al. Cancer Cell-Selective Targeting by Arylcyclopropylamine-Vorinostat Conjugates. ACS Medicinal Chemistry Letters. 2022
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