Research theme for competitive and other funds (1)：
2015 - 2018 Molecular identification of amino acid sensor and its function in mTORC1 signaling pathway
Papers (33)：
Yu Ma, Suguru Okuda, Hiroki Okanishi, Minhui Xu, Chunhuan Jin, Hitoshi Endou, Ryuichi Ohgaki, Yoshikatsu Kanai. Upregulation of ATF4 mediates the cellular adaptation to pharmacologic inhibition of amino acid transporter LAT1 in pancreatic ductal adenocarcinoma cells. Journal of Pharmacological Sciences. 2024. 155. 1. 14-20
Xingming Liu, Kou Nishikubo, Ryuichi Ohgaki, Hiroki Okanishi, Suguru Okuda, Minhui Xu, Yoshikatsu Kanai. Identification of tumor-suppressive miRNAs that target amino acid transporter LAT1 and exhibit anti-proliferative effects on cholangiocarcinoma cells. Journal of Pharmacological Sciences. 2024
Peng Lu, Jinyan Jiang, Chang Liu, Suguru Okuda, Hideaki Itoh, Ken Okamoto, Michio Suzuki, Koji Nagata. Molecular Mechanism of Fe3+ Binding Inhibition to Vibrio metschnikovii Ferric Ion-Binding Protein, FbpA, by Rosmarinic Acid and its Hydrolysate, Danshensu. Protein Science. 2023
Peng Lu, Jiaqiao Zhou, Sibo Wei, Konosuke Takada, Hayato Masutani, Suguru Okuda, Ken Okamoto, Michio Suzuki, Tomoya Kitamura, Kentaro Masujin, et al. Comparative genomic and transcriptomic analyses of African swine fever virus strains. Computational and structural biotechnology journal. 2023. 21. 4322-4335
Kou Nishikubo, Ryuichi Ohgaki, Hiroki Okanishi, Suguru Okuda, Minhui Xu, Hitoshi Endou, Yoshikatsu Kanai. Pharmacologic inhibition of LAT1 predominantly suppresses transport of large neutral amino acids and downregulates global translation in cancer cells. Journal of Cellular and Molecular Medicine. 2022
Bacterial Membranes: Structural and Molecular Biology
Caister Academic Press 2014
Professional career (1)：
博士(農学) (東京大学)
Work history (5)：
2021/04 - 現在 The University of Tokyo Graduate School of Agricultural and Life Sciences
2013/07 - 2021/03 Osaka University
2012/04 - 2013/06 Harvard University
2009/04 - 2012/03 Harvard University
2008/04 - 2009/03 The University of Tokyo Institute of Molecular and Cellular Biosciences
Awards (1)：
2018/06 - 日本蛋白質科学会 若手奨励賞優秀賞
Association Membership(s) (5)：
THE JAPANESE PHARMACOLOGICAL SOCIETY
, THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
, THE JAPANESE BIOCHEMICAL SOCIETY
, PROTEIN SCIENCE SOCIETY OF JAPAN
, JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY
