Okuda Suguru

オクダスグル | Okuda Suguru

Affiliation and department：

Research field (1)： Molecular biology

Research theme for competitive and other funds (12)：

2024 - 2028 細菌セルロース分泌システムにおけるセルロース輸送の観察法確立および分子機構解析
2020 - 2023 新規細胞内アミノ酸センサーの同定と分子機構解明および創薬標的としての可能性の探索
2019 - 2022 Study on the amino acid signaling via transporters and receptors for the pharmacologic control of cellular metabolism
2018 - 2020 Study on the effects of amino acid availability on life span and the underlying molecular mechanisms
2016 - 2019 リソソーム内アミノ酸情報のmTORへの伝達を担う新因子の探索と機能的意義の解明

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Papers (38)：

Sibo Wei, Li Li, Peng Lu, Michio Suzuki, Suguru Okuda, Ken Okamoto, Hideaki Itoh, Koji Nagata. Identification of a novel subtilisin-derived peptide, SC-(1-31), with cytotoxic activity. Biochemical and Biophysical Research Communications. 2025. 742. 151101-151101
Jinyan Jiang, Suguru Okuda, Hideaki Itoh, Ken Okamoto, Hiromi Nakanishi, Michio Suzuki, Peng Lu, Koji Nagata. Structure-Guided Discovery of a Potent Inhibitor of the Ferric Citrate Binding Protein FecB in Vibrio Bacteria. Angewandte Chemie (International ed. in English). 2024. e202411688
Yu Ma, Suguru Okuda, Hiroki Okanishi, Minhui Xu, Chunhuan Jin, Hitoshi Endou, Ryuichi Ohgaki, Yoshikatsu Kanai. Upregulation of ATF4 mediates the cellular adaptation to pharmacologic inhibition of amino acid transporter LAT1 in pancreatic ductal adenocarcinoma cells. Journal of Pharmacological Sciences. 2024. 155. 1. 14-20
Yukihiko Narita, Arisa Tamura, Shiori Hatakeyama, Seiya Uemura, Atsuko Miura, Asami Haga, Noriko Tsuji, Nozomi Fujie, Yukina Izumi, Taku Sugawara, et al. The components of the AhR-molecular chaperone complex differ depending on whether the ligands are toxic or non-toxic. FEBS Letters. 2024. 598. 12. 1478-1490
Xingming Liu, Kou Nishikubo, Ryuichi Ohgaki, Hiroki Okanishi, Suguru Okuda, Minhui Xu, Yoshikatsu Kanai. Identification of tumor-suppressive miRNAs that target amino acid transporter LAT1 and exhibit anti-proliferative effects on cholangiocarcinoma cells. Journal of Pharmacological Sciences. 2024

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MISC (3)：

升谷颯, 國保健浩, 渡邉瑞希, 播谷亮, LU Peng, 奥田傑, 岡本研, 鈴木道生, 永田宏次, 伊藤英晃. Antibody-based analysis of African swine fever virus. 日本分子生物学会年会プログラム・要旨集(Web). 2022. 45th
本田裕佳, 住田喬哉, 伊藤光洋, LU Yi, 降旗一夫, 堀吉満, 奥田傑, 伊藤秀晃, 岡本研, 鈴木道生, et al. Metabolomic analysis of honey samples using NMR and GC-MS. 日本分子生物学会年会プログラム・要旨集(Web). 2022. 45th
大垣隆一, 大森崇弘, 原早織, 中込咲綾, 金井正美, 兼田(中島)加珠子, 奥田傑, 永森收志, 金井好克. アミノ酸トランスポーターLAT1は胎盤合胞体性栄養膜の形成に必須である:膜融合関連因子4F2hcの細胞膜提示による細胞融合への寄与. 日本分子生物学会年会プログラム・要旨集(Web). 2016. 39th

Books (1)：

Bacterial Membranes: Structural and Molecular Biology
Caister Academic Press 2014

Professional career (1)：

博士(農学) (東京大学)

Work history (5)：

2021/04 - 現在 The University of Tokyo Graduate School of Agricultural and Life Sciences
2013/07 - 2021/03 Osaka University
2012/04 - 2013/06 Harvard University
2009/04 - 2012/03 Harvard University
2008/04 - 2009/03 The University of Tokyo Institute of Molecular and Cellular Biosciences

Committee career (1)：

2019/03 - 現在日本薬理学会学術評議員

Awards (1)：

2018/06 - 日本蛋白質科学会若手奨励賞優秀賞

Association Membership(s) (4)：

THE JAPANESE PHARMACOLOGICAL SOCIETY , THE JAPANESE BIOCHEMICAL SOCIETY , PROTEIN SCIENCE SOCIETY OF JAPAN , JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY

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