Rchr
J-GLOBAL ID:201801015449028711   Update date: Jan. 30, 2024

Oshima Shigeru

オオシマ シゲル | Oshima Shigeru
Affiliation and department:
Job title: Professor
Research field  (1): Gastroenterology
Research keywords  (5): オートファジー ,  ユビキチン ,  腫瘍 ,  腸管免疫 ,  炎症性腸疾患
Research theme for competitive and other funds  (8):
  • 2021 - 2023 腸内環境における生命金属の役割
  • 2018 - 2020 分子応答解析に基づく肉芽腫形成モデルの樹立
  • 2016 - 2017 ネクロプトーシス回避機構の解明
  • 2015 - 2017 持続炎症モデルを用いた腸管上皮細胞スパイラル形質転換による発がん機構解析
  • 2013 - 2015 炎症性腸疾患における自己抗体産生機構の解明
Show all
Papers (77):
  • Akiko Tamura, Go Ito, Hiroki Matsuda, Yoichi Nibe-Shirakihara, Yuichi Hiraoka, Sayuki Kitagawa, Yui Hiraguri, Sayaka Nagata, Emi Aonuma, Kana Otsubo, et al. Zranb1-mutant mice display abnormal colonic mucus production and exacerbation of DSS-induced colitis. Biochemical and biophysical research communications. 2022. 628. 147-154
  • Ai Minamidate, Michio Onizawa, Chikako Saito, Rie Hikichi, Tomoaki Mochimaru, Mai Murakami, Chiharu Sakuma, Takehito Asakawa, Yuichi Hiraoka, Shigeru Oshima, et al. A potent endocytosis inhibitor Ikarugamycin up-regulates TNF production. Biochemistry and biophysics reports. 2021. 27. 101065-101065
  • Naoya Tsugawa, Daiki Yamada, Taro Watabe, Michio Onizawa, Shuang Wang, Yasuhiro Nemoto, Shigeru Oshima, Takeshi Tsubata, Takahiro Adachi, Yohei Kawano, et al. Corrigendum to "CEACAM1 specifically suppresses B cell receptor signaling-mediated activation". Biochemical and biophysical research communications. 2021. 565. 97-97
  • Takehito Asakawa, Michio Onizawa, Chikako Saito, Rie Hikichi, Daiki Yamada, Ai Minamidate, Tomoaki Mochimaru, Shun-Ichiro Asahara, Yoshiaki Kido, Shigeru Oshima, et al. Oral administration of D-serine prevents the onset and progression of colitis in mice. Journal of gastroenterology. 2021. 56. 8. 732-745
  • Reiko Kuno, Go Ito, Ami Kawamoto, Yui Hiraguri, Hady Yuki Sugihara, Sayaka Takeoka, Sayaka Nagata, Junichi Takahashi, Mao Tsuchiya, Sho Anzai, et al. Notch and TNF-α signaling promote cytoplasmic accumulation of OLFM4 in intestinal epithelium cells and exhibit a cell protective role in the inflamed mucosa of IBD patients. Biochemistry and biophysics reports. 2021. 25. 100906-100906
more...
MISC (32):
  • Masanori Kobayashi, Shigeru Oshima, Chiaki Maeyashiki, Yoichi Nibe, Kana Otsubo, Mamoru Watanabe. THE UBIQUITIN HYBRID GENE UBA52 REGULATES CELL CYCLE AND UBIQUITINATION OF RIBOSOME IN COLON CANCER. GASTROENTEROLOGY. 2017. 152. 5. S1038-S1039
  • Fumiaki Ishibashi, Hiromichi Shimizu, Toru Nakata, Satoru Fujii, Kohei Suzuki, Ami Kawamoto, Sho Anzai, Reiko Kuno, Sayaka Nagata, Go Ito, et al. LINEAGE TRACING REVEALS CONTRIBUTION OF ATOH1(+) CELL-DERIVED STEM CELLS IN THE HOMEOSTASIS, REPAIR, AND CARCINOGENESIS OF THE INTESTINAL EPITHELIUM. GASTROENTEROLOGY. 2017. 152. 5. S169-S169
  • Masanori Kobayashi, Shigeru Oshima, Kana Otsubo, Yoichi Nibe, Chiaki Maeyashiki, Mamoru Watanabe. The ubiquitin-hybrid gene UBA52 regulates TNFa signaling in colon cancer. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY. 2016. 31. 145-146
  • Shuji Hibiya, Kiichiro Tsuchiya, Sho Watanabe, Tomoaki Shirasaki, Ryu Nishimura, Shigeru Oshima, Ryuichi Okamoto, Tetsuya Nakamura, Mamoru Watanabe. Construction of in vitro model of ulcerative colitis using mouse primary colonic organoid. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY. 2016. 31. 151-151
  • Shigeru Oshima, Chiaki Maeyashiki, Kana Otsubo, Masanori Kobayashi, Yoichi Nibe, Mamoru Watanabe. Identification of novel autophagosome formation regulators in intestinal epithelial cells. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY. 2016. 31. 122-122
more...
Education (2):
  • 2000 - 2004 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences
  • 1991 - 1997 Tokyo Medical and Dental University Faculty of Medicine School of Medicine
Work history (10):
  • 2022 - Tokyo Medical and Dental University Institute of Research
  • 2018 - Tokyo Medical and Dental University
  • 2013 - 東京医科歯科大学 消化器病態学 助教
  • 2011 - 東京医科歯科大学消化管先端治療学 助教
  • 2009 - University of California, San Francisco Assistant Adjunct Professor
Show all
Awards (13):
  • 2020/04 - 令和2年度 文部科学省科学研究費補助金 基盤研究(C):19K08461 「ヒトiPS細胞由来胆管細胞培養系を用いた胆管癌における新規発癌機序の解明」 研究代表者:小林正典 分担研究者:柿沼 晴、土屋輝一郎、大島 茂 ヒトiPS細胞由来胆管細胞培養系を用いた胆管癌における新規発癌機序の解明
  • 2020/04 - 令和2年度 文部科学省科学研究費補助金 基盤研究(C):18K07934 「分子応答解析に基づく肉芽腫形成モデルの樹立」 研究代表者:大島 茂 連携研究者:渡辺 守 分子応答解析に基づく肉芽腫形成モデルの樹立
  • 2019/04 - 令和元年度 文部科学省科学研究費補助金 基盤研究(C):18K07934 「分子応答解析に基づく肉芽腫形成モデルの樹立」 研究代表者:大島 茂 分子応答解析に基づく肉芽腫形成モデルの樹立
  • 2019/04 - 令和元年度 文部科学省研究費補助金 基盤研究(C):19K08461 「ヒトiPS細胞由来胆管細胞培養系を用いた胆管癌における新規発癌機序の解明」 研究代表者:小林正典 研究分担者:柿沼 晴、土屋輝一郎、大島 茂 ヒトiPS細胞由来胆管細胞培養系を用いた胆管癌における新規発癌機序の解明
  • 2018/04 - 平成30年度 文部科学省科学研究費補助金 基盤研究(C) 「分子応答解析に基づく肉芽腫形成モデルの樹立」研究代表者:大島 茂
Show all
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page