Rchr
J-GLOBAL ID：201801015605524767
Update date: Apr. 24, 2024
Mizuguchi Mariko
Mizuguchi Mariko
Affiliation and department：
Research field (1)：
Molecular biology
Research keywords (2)：
Adult T-cell leukemia/lymphoma (ATL)
, Human T-cell leukemia virus type 1 (HTLV-1)
Research theme for competitive and other funds (3)：
- 2024 - 2027 リンパ節に局在するATL細胞の増殖機構の解明
- 2019 - 2021 ATLにおける制御性T細胞の選択的な増殖機構:OX40L/OX40に着目して
- 2017 - 2019 DNA複製異常による成人T細胞白血病発症機構の解明
Papers (12)：
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Yuetsu Tanaka, Reiko Tanaka, Naoki Imaizumi, Mariko Mizuguchi, Yoshiaki Takahashi, Masaki Hayashi, Takashi Miyagi, Junnosuke Uchihara, Kazuiku Ohshiro, Hiroaki Masuzaki, et al. A protective role of HTLV-1 gp46-specific neutralizing and antibody-dependent cellular cytotoxicity-inducing antibodies in progression to adult T-cell leukemia (ATL). Frontiers in Immunology. 2022. 13. 921606-921606
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Mariko Mizuguchi, Mitsuyoshi Takatori, Shugo Sakihama, Manami Yoshita-Takahashi, Naoki Imaizumi, Yoshiaki Takahashi, Hiroo Hasegawa, Kennosuke Karube, Takuya Fukushima, Masataka Nakamura, et al. Acute type adult T-cell leukemia cells proliferate in the lymph nodes rather than in peripheral blood. Cancer Gene Therapy. 2022
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Megumi Kato, Naoki Imaizumi, Reiko Tanaka, Mariko Mizuguchi, Masaki Hayashi, Takashi Miyagi, Junnosuke Uchihara, Kazuiku Ohshiro, Junpei Todoroki, Kennosuke Karube, et al. Elevation of the Plasma Levels of TNF Receptor 2 in Association with Those of CD25, OX40, and IL-10 and HTLV-1 Proviral Load in Acute Adult T-Cell Leukemia. Viruses. 2022. 14. 4. 751-751
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Mariko Mizuguchi, Toshifumi Hara, Manami Yoshita-Takahashi, Takashi Kohda, Yuetsu Tanaka, Masataka Nakamura. Promoter CpG methylation inhibits Krüppel-like factor 2 (KLF2)-Mediated repression of hTERT gene expression in human T-cells. Biochemistry and Biophysics Reports. 2021. 26. 100984-100984
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Hironori Kato, Kohki Okabe, Masato Miyake, Kazuki Hattori, Tomohiro Fukaya, Kousuke Tanimoto, Shi Beini, Mariko Mizuguchi, Satoru Torii, Satoko Arakawa, et al. ER-resident sensor PERK is essential for mitochondrial thermogenesis in brown adipose tissue. Life science alliance. 2020. 3. 3
ｍore...
MISC (2)：
Professional career (1)：
Work history (4)：
- 2020/04 - 2024/03 University of the Ryukyus Department of Investigative Medicine, Graduate School of Medicine
- 2018/02 - 2020/03 University of the Ryukyus Department of Immunology, Graduate School of Medicine Assistant professor
- 2012/04 - 2018/01 Tokyo Medical and Dental University Human Gene Sciences Center Assistant professor
- 2010/04 - 2012/03 Tokyo Medical and Dental University Human Gene Sciences Center
Awards (2)：
- 2023/04 - 琉球大学 琉球医学会 特別研究推進事業-特推琉球医学会賞-
- 2022/03 - 琉球大学 琉球大学医学部研究奨励賞
Association Membership(s) (2)：
日本HTLV-1学会
, THE JAPANESE CANCER ASSOCIATION
