J-GLOBAL ID:201801015771050099   Update date: Oct. 12, 2021

Jun Fang

Jun Fang
Affiliation and department:
Job title: Associate Professor
Research field  (4): Nanobioscience ,  Pharmacology ,  Pharmaceuticals - analytical and physicochemistry ,  Tumor diagnostics and therapeutics
Research keywords  (6): CO ,  Cancer treatment and prevention ,  ROS and inflammation ,  EPR effect ,  DDS ,  Nanomedicine
Research theme for competitive and other funds  (9):
  • 2019 - 2022 婦人科癌へのHPMA-ZnPPを用いた光線力学的治療の臨床応用に向けた検討
  • 2019 - 2022 Augmentation of EPR effect and therapeutic effect of nanomedicine by inhibiting off-targeting delivery
  • 2016 - 2019 Augmentation of EPR effect and therapeutic effect of nanomedicine by improving tumor microenvironment
  • 2013 - 2016 Design and evaluation of the theranostic potential of tumor-targeted polymeric micelle of zinc protoporphyrin
  • 2011 - 2014 蛍光内視鏡をめざした高分子型分子プローブの創製
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Papers (97):
  • Jie Hu, Xianbing Song, Danlin Li, Shuai Zhao, Yuhui Wan, Jun Fang, Shichen Zhang. Interaction of smoking and being bullied on suicidal behaviors: a school-based cross-sectional survey in China. Environmental health and preventive medicine. 2021. 26. 1. 79-79
  • Atsushi Makimoto, Jun Fang, Hiroshi Maeda. Development of a Selective Tumor-Targeted Drug Delivery System: Hydroxypropyl-Acrylamide Polymer-Conjugated Pirarubicin (P-THP) for Pediatric Solid Tumors. Cancers. 2021. 13. 15
  • Waliul Islam, Shintaro Kimura, Rayhanul Islam, Ayaka Harada, Katsuhiko Ono, Jun Fang, Takuro Niidome, Tomohiro Sawa, Hiroshi Maeda. EPR-Effect Enhancers Strongly Potentiate Tumor-Targeted Delivery of Nanomedicines to Advanced Cancers: Further Extension to Enhancement of the Therapeutic Effect. Journal of personalized medicine. 2021. 11. 6
  • Rayhanul Islam, Shanghui Gao, Waliul Islam, Vladimír Šubr, Jian-Rong Zhou, Kazumi Yokomizo, Tomáš Etrych, Hiroshi Maeda, Jun Fang. Unraveling the role of Intralipid in suppressing off-target delivery and augmenting the therapeutic effects of anticancer nanomedicines. Acta biomaterialia. 2021. 126. 372-383
  • Bingdong Song, Cheng Zhang, Weirong Hu, Chunyu Guo, Zhengmei Xia, Wanxia Hu, Mingqiang Qin, Weiying Jiang, Jinwei Lv, Dexiang Xu, et al. Nano-designed carbon monoxide donor SMA/CORM2 exhibits protective effect against acetaminophen induced liver injury through macrophage reprograming and promoting liver regeneration. Journal of controlled release : official journal of the Controlled Release Society. 2021. 331. 350-363
Books (4):
  • PEGylated zinc protoporphyrin: a micelle forming polymeric drug for cancer therapy
    In: Sahoo S et al (eds.), Nanotechnology in Health Care, Singapore, Pan Stanford Publisher, 2012
  • Tumor targeted macromolecular drug delivery based on the enhanced permeability and retention effects in solid tumor.
    In: Lu Y, Mahato RI (eds.), Pharmacrutical Perspective of Cancers Therapeutics. New York: AAPS-Springer, 2009
  • Enhanced permeability and retention (EPR) effect and tumor-selective delivery of anticancer drugs.
    In V Torchilin (ed.), Delivery of Protein and Peptide Drugs in Cancer. Imperial College Press, London 2006
  • Factors and mechanism of EPR effect and clinical outlook of SMANCS.
    In: R. Han (ed.), Cancer Chemoprevention and Drug Therapy of the New Millenium. People’s Military Medical Press, Beijing, China 2005
Education (3):
  • 1999 - 2003 Kumamoto University
  • 1995 - 1998 中国医科大学
  • 1989 - 1995 白求恩医科大学(現吉林大学医学部)
Work history (4):
  • 2010/04 - 現在 Sojo University
  • 2005/04 - 2010/03 Sojo University
  • 2003/09 - 2005/03 Duke University Medical Center Research Associate
  • 2003/04 - 2003/08 Kumamoto University
Awards (1):
  • 2020/12 - 崇城大学 ベストリサーチアワード
Association Membership(s) (4):
日本D D S学会評議員 ,  日本薬学会 ,  日本DDS学会 ,  日本癌学会
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