Research keywords (3)：
CD271
, squamous cell carcinoma
, head and neck squamous cell carcinoma
Research theme for competitive and other funds (9)：
2022 - 2025 下咽頭癌の癌幹細胞を制御するCD271の転写制御機構の解明
2022 - 2025 下咽頭癌特異的抗体の開発と光免疫療法への応用
2021 - 2024 扁平上皮がんに特異的なmRNA依存性がん幹細胞維持機構
2019 - 2023 下咽頭癌特異的mRNAによる増殖機構の解明
2019 - 2023 肺扁平上皮癌におけるCD271標的治療開発のための基礎検討
2018 - 2022 The tumor initiating cell asa new therapeutic target for hypopharyngeal cancer.
2017 - 2021 Role of CDKN1C in hypopharyngeal cancer
2016 - 2019 CD271 is a functional and therapeutic-targetable marker of cell proliferation in hypopharyngeal cancer.
2014 - 2016 Possible role of CD271 for maintaining stemness and application to treatment in HPC.
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Papers (29)：
Akihiro Yasumoto, Haruna Fujimori, Mai Mochizuki, Rie Shibuya-Takahashi, Mao Nakamura-Shima, Norihisa Shindo, Kazunori Yamaguchi, Daisuke Fukushi, Yuta Wakui, Takahiro Sugai, et al. BEX2 is poor prognostic factor and required for cancer stemness in gastric cancer. Biochemical and biophysical research communications. 2023. 655. 59-67
Akira Nakazato, Mai Mochizuki, Rie Shibuya-Takahashi, Haruna Fujimori, Keitaro Fujii, Satoshi Saijoh, Shinkichi Morita, Tomoko Yamazaki, Takayuki Imai, Ikuro Sato, et al. RELA is required for CD271 expression and stem-like characteristics in hypopharyngeal cancer. Scientific reports. 2022. 12. 1. 17751-17751
Keitaro Fujii, Shinkichi Morita, Mai Mochizuki, Rie Shibuya-Takahashi, Haruna Fujimori, Kazunori Yamaguchi, Jiro Abe, Tomoko Yamazaki, Takayuki Imai, Kazuo Sugamura, et al. Establishment of a monoclonal antibody against glycosylated CD271 specific for cancer cells in immunohistochemistry. Cancer science. 2022. 113. 8. 2878-2887
Shin Ito, Aya Hashimoto, Kazunori Yamaguchi, Sadafumi Kawamura, Shingo Myoen, Maki Ogawa, Ikuro Sato, Takamichi Minato, Shingo Miyabe, Akira Nakazato, et al. A novel 8.57-kb deletion of the upstream region of PRKAR1A in a family with Carney complex. Molecular genetics & genomic medicine. 2022. 10. 3. e1884
Takamichi Minato, Shin Ito, Bin Li, Haruna Fujimori, Mai Mochizuki, Kazunori Yamaguchi, Keiichi Tamai, Muneaki Shimada, Hideki Tokunaga, Shogo Shigeta, et al. Liquid biopsy with droplet digital PCR targeted to specific mutations in plasma cell-free tumor DNA can detect ovarian cancer recurrence earlier than CA125. Gynecologic oncology reports. 2021. 38. 100847-100847
