MIZUNO Seiya

ミズノセイヤ | MIZUNO Seiya

Affiliation and department：
Job title： Professor
Homepage URL (1)： http://www.md.tsukuba.ac.jp/basic-med/lab-animal/

Research field (1)： Laboratory animal science

Research theme for competitive and other funds (21)：

2022 - 2025 Functional analysis of inflammation-related scar genes based on fibroblast differentiation lineage and its application
2022 - 2025 Functional analysis and developing application model of inflammation-genes viewed on lineage-specific differentiation of fibroblasts
2022 - 2025 新規direct-cKOシステムでの必須遺伝子探索とその網羅的解析基盤の構築
2021 - 2025 Investigation of wound healing in embryo and adult using spatial gene expression analysis
2021 - 2024 Developing a versatile technique to create transgenic rodents and medium sized animals

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Papers (131)：

Yung Ting Hsiao, Yohko Yoshida, Shujiro Okuda, Manabu Abe, Seiya Mizuno, Satoru Takahashi, Hironori Nakagami, Ryuichi Morishita, Kenya Kamimura, Shuji Terai, et al. PCPE-1, a brown adipose tissue-derived cytokine, promotes obesity-induced liver fibrosis. The EMBO journal. 2024
Arai, Junya, Hayakawa, Yoku, Tateno, Hiroaki, Murakami, Keita, Hayashi, Takeru, Hata, Masahiro, Matsushita, Yuki, Kinoshita, Hiroto, Abe, Sohei, Kurokawa, Ken, et al. Impaired Glycosylation of Gastric Mucins Drives Gastric Tumorigenesis and Serves as a Novel Therapeutic Target. Gastroenterology. 2024. 167. 3. 505-521.e19
Katoh, Manami, Nomura, Seitaro, Yamada, Shintaro, Ito, Masamichi, Hayashi, Hiroki, Katagiri, Mikako, Heryed, Tuolisi, Fujiwara, Takayuki, Takeda, Norifumi, Nishida, Miyuki, et al. Vaccine Therapy for Heart Failure Targeting the Inflammatory Cytokine Igfbp7. CIRCULATION. 2024. 150. 5. 374-389
Lee, Dong-Joon, Kim, Pyunggang, Kim, Hyun-Yi, Park, Jinah, Lee, Seung-Jun, An, Haein, Heo, Jin Sun, Lee, Min-Jung, Ohshima, Hayato, Mizuno, Seiya, et al. MAST4 regulates stem cell maintenance with DLX3 for epithelial development and amelogenesis. EXPERIMENTAL AND MOLECULAR MEDICINE. 2024. 56. 7. 1606-1619
Wakasugi, Daiki, Kondo, Shinji, FERDOUSI, Farhana, Mizuno, Seiya, Yada, Akira, Tominaga, Ken-ichi, Takahashi, Satoru, Isoda, Hiroko. A rare olive compound oleacein functions as a TrkB agonist and mitigates neuroinflammation both in vitro and in vivo. CELL COMMUNICATION AND SIGNALING. 2024. 22. 1

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MISC (16)：

高島さつき, 武藤真長, 渡部千里, 岡村永一, 松本翔馬, 築山智之, 藤井勢津子, 久保田慶顕, 水野聖哉, 杉山文博, et al. Exoc3l4 is essential for placental angiogenesis in mice. 日本分子生物学会年会プログラム・要旨集(Web). 2023. 46th
高島さつき, 武藤真長, 岡村永一, 松本翔馬, 久保田義顕, 水野聖哉, 杉山文博, 高橋智, 水谷健一, 依馬正次. マウス胎盤の血管新生におけるExoc3l4遺伝子の機能解明. 日本血管生物医学会学術集会プログラム・抄録集. 2023. 31st (CD-ROM)
藤山知之, 管野里美, 堀田典子, 柿崎美代, 一久綾, 恒岡洋右, 阿部学, 望月綾子, セオーネコラッゾパトリシア, 宮崎峻弘, et al. 非選択的陽イオンチャネルNalcn遺伝子改変マウスを用いたレム睡眠制御機構の解析. 日本神経化学会大会抄録集(Web). 2022. 65th
玉里友宏, 池田祥久, 池田祥久, 藤木雄太, 小林慶子, 綾部信哉, 岩間瑞穂, 水野聖哉, 杉山文博, 吉木淳. 電気穿孔法を用いた様々な近交系での遺伝子改変マウス作製. 日本実験動物学会総会講演要旨集(Web). 2021. 68th
久野朗広, 池田祥久, 綾部信哉, 高橋智, 高橋智, 杉山文博, 水野聖哉. DAJIN:新しいゲノム編集動物の解析技術. 日本生化学会大会(Web). 2021. 94th

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Books (2)：

Lectures and oral presentations (42)：

Autism-associated Sparcl1/Hevin mutant has impacts on persistent angiogenesis
(Society for Neuroscience 2024)
多中心性手根足根骨溶解症(MCTO)関連腎症に対するMAFB-IGF1-PI3K/AKTシグナル抑制は潜在的な治療選択肢である
(第67回日本腎臓学会学術総会)
The impairment in subcellular localisation of c-KIT and GDF9 caused by the loss of a complex membrane trafficking factor component in oocyte
(第46回日本分子生物学会年会)
Efficient Direct-cKO method for rapid in vivo functional analysis
(9th Asian Federation of Laboratory Animal Science Associations Congress 2023)
Hevin/Sparcl1の変異によるASD病態形成への新たな洞察
(第46回日本神経科学大会)

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Professional career (2)：

Work history (3)：

Association Membership(s) (2)：

日本ゲノム編集学会 , 日本実験動物学会

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