Hirata Eishu

ヒラタエイシュウ | Hirata Eishu

Affiliation and department：
Job title： Associate Professor

Research field (3)： Tumor biology , Neurosurgery , Neurology

Research keywords (14)： Brain tumor , metastatic brain tumor , Malignant glioma , Tumor microenvironment , Astrocyte , Microglia , Cancer Metastasis , Drug Resistance , Bioimaging , FRET imaging , Neurosurgery , Neurology , Migraine , Satellite glia

Research theme for competitive and other funds (10)：

2024 - 2027 ミクログリア制御によるがん脳転移治療・予防戦略の開発
2023 - 2025 グリオーマ関連ミクログリア・マクロファージの機能制御
2022 - 2025 Development of treatment strategies for cancer brain metastasis targeting metabotropic glutamate receptors
2020 - 2023 がん脳転移微小環境分子基盤の統合的理解と治療への応用
2019 - 2022 Epigenetic analysis and drug development with cell-reprogramming technology in atypical teratoid/rhabdoid tumor

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Papers (37)：

Kumiko Taniguchi, Kei Sugihara, Takashi Miura, Daisuke Hoshi, Susumu Kohno, Chiaki Takahashi, Eishu Hirata, Etsuko Kiyokawa. Cholesterol synthesis is essential for the growth of liver metastasis-prone colorectal cancer cells. Cancer science. 2024
Giovanni Giangreco, Antonio Rullan, Yutaka Naito, Dhruva Biswas, Yun-Hsin Liu, Steven Hooper, Pablo Nenclares, Shreerang Bhide, Maggie Chon U Cheang, Probir Chakravarty, et al. Cancer cell - Fibroblast crosstalk via HB-EGF, EGFR, and MAPK signaling promotes the expression of macrophage chemo-attractants in squamous cell carcinoma. iScience. 2024. 27. 9. 110635-110635
Kojiro Ishibashi, Eishu Hirata. Multifaceted interactions between cancer cells and glial cells in brain metastasis. Cancer science. 2024
Natsuko Kondo, Tadatoshi Kinouchi, Manabu Natsumeda, Juntaro Matsuzaki, Eishu Hirata, Yoshinori Sakurai, Masayasu Okada, Minoru Suzuki. Profile of miRNAs in small extracellular vesicles released from glioblastoma cells treated by boron neutron capture therapy. Journal of neuro-oncology. 2024. 168. 1. 91-97
Takeru Ishizaki, Daisuke Tanaka, Kojiro Ishibashi, Kenji Takahashi, Eishu Hirata, Kosuke Kuroda. Cell Damage Mechanisms during Cryopreservation in a Zwitterion Solution and Its Alleviation by DMSO. The journal of physical chemistry. B. 2024. 128. 16. 3904-3909

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MISC (27)：

Kuroda Kosuke, Hirata Eishu. Zwitterionic Liquids as Novel Solvents and Cryoprotectants. Cryobiology and Cryotechnology. 2023. 69. 1. 7-12
Kuroda Kosuke, Hirata Eishu. Novel solvents for life sciences. 2022. 94. 2. 298-301
丹下正一朗, 平野朋美, 井戸川雅史, 平田英周, 井本逸勢, 時野隆至. 膵臓がんにおける新規予後予測遺伝子の機能解析. 日本癌学会総会記事. 2021. 80回. [J15-6]
平田英周. 中枢神経系における治療抵抗性腫瘍微小環境の本態解明-Elucidation of the nature of treatment-resistant tumor microenvironment in the central nervous system-2018年度研究奨励金受領報告. 東京生化学研究会助成研究報告集. 2019. 34. 251-255
平田英周. 脳転移がん細胞の休眠維持と破綻の機構解明. 上原記念生命科学財団研究報告集. 2017. 31. 5p

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Patents (7)：

細胞死誘導剤、医薬組成物、及びがん細胞検出薬
現在非公開(特願2022-098339の優先権主張出願)
現在非公開
現在非公開
脳転移がん抑制剤又は治療剤

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Books (4)：

がん生物学イラストレイテッド(第2版)第9章 6. 脳腫瘍
羊土社 2019 ISBN:9784758120968
BRAF阻害薬による悪性黒色腫微小環境のparadoxical activationの分子機構
がん分子標的治療 14巻1号遺伝子解析に基づく新しい分子標的治療 2016
がん細胞とがん関連線維芽細胞の相互作用
生体の科学 67巻2号細胞の社会学-細胞間で繰り広げられる協調と競争 2016
イギリスの脳血管障害急性期医療
脳血管障害の急性期マネジメント(監修・橋本信夫、編・清水宏明)文光堂 2014 ISBN:9784830624018

Education (2)：

- 2010 Kyoto University Graduate School of Medicine
- 2002 Kyoto University School of Medicine

Professional career (2)：

M.D. (Kyoto University)
Ph.D. (Kyoto University)

Work history (9)：

2024/08 - 現在 WPI Nano Life Science Institute, Kanazawa University Professor
2024/08 - 現在 Cancer Research Institute of Kanazawa University Division of Tumor Cell Biology and Bioimaging Professor
2018/09 - 2024/07 WPI Nano Life Science Institute, Kanazawa University Associate Professor
2018/09 - 2024/07 Cancer Research Institute of Kanazawa University Division of Tumor Cell Biology and Bioimaging Associate Professor
2015/08 - 2018/08 Kanazawa Medical University Senior Assistant Professor

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