Araki Yoshihiko

2020 - 2023 可溶型CD163分子による遊離ヘモグロビン細胞毒性回避機構解明と分子創薬への応用

2020 - 2023 卵管分泌因子機能不全による新規不育症モデル動物の胚・雌性生殖管超微細構造の分析

2019 - 2021 Identification and analysis of a new group of diseases with a common etiology of abnormal immune response to embryonic signals

2018 - 2021 Oviduct as the site of fertilization and early embryonic development: Verification of its physiological functions using genetically engineering hamster model for clinical application

2018 - 2021 受精/初期発生の場としての卵管:その生理機能の分子論的検証と臨床応用への基盤構築

2017 - 2020 Promoting mechnisms of embryonic signals in embryo implantation induced by the immune system

2016 - 2020 Study of reproductive biological functions of bisecting GlcNAc using glycotechnology and immunological methods

2017 - 2020 多形核白血球の挙動から見る女性の生理学的特性:細胞レベルに性差はあるか?

2017 - 2019 Identification and analysis of circulating embryonic stem cells derived from human chorionic stroma at early stage

2017 - 2019 Physiological characteristics of female in terms of polymorphonuclear leukocyte behavior: Are there sex-differences at the cellular level?

2016 - 2019 Analysis of soluble factor in menstrual blood or follicular fluid associated with fallopian tubal carcinogenesis

2015 - 2018 Development of a pathophysiological evaluation method for hypertensive disorders of pregnancy by simultaneous quantitation analysis of multiple disease biomarkers.

2016 - 2017 Analysis of chorionic villi-derived embryo stem cells by novel sten cell markers, laeberin and hTERT

2014 - 2017 Identification of embryo-derived implantation-inducing factors (embryonic signals) and their clinical application

2013 - 2016 Structural and functional analyses of reproduction-specific carbohydrate antigen recognized by an auto-antibody, Ts4

2012 - 2016 Developent of new drug delivery system using targeted liposomes for age-related macular degeneration

2013 - 2016 自然抗体により認識される生殖過程特異糖鎖抗原の構造及び生理機能の解明

2013 - 2015 Platelet-induced re-epithelialization and its failure

2012 - 2015 Development of cancer/testis antigen, TEX101-targeted therapy in head and neck squamous cell carcinoma

2012 - 2014 Challenging study to clarify mechanisms of multiple organ failure

2011 - 2014 Analysis of maternal recognition through embryo-specific sugar antigen and its inducing mechanisms for embryo implantation and placentation

2011 - 2013 妊娠高血圧症候群予知診断法の開発

2009 - 2012 遺伝子工学・細胞生物学的アプローチによる配偶子形成過程における分子基盤の解明

2012 - 2012 Induction of immune-tolerance by a novel human trophoblast-specific soluble factor, laeverin

2011 - 2011 Induction of tissue remodeling of reproductive organs using gligl stem cell-derived factors

2009 - 2011 Epigenetic control of gene expression associated with adult diseases due to fetal nutritional factors

2009 - 2011 Elucidation of the molecular basis on mammalian gametogenesis by genetic engineering and cell biological techniques

2009 - 2011 Expression and clinical analysis of a novel cancer/testis antigen, TEX101 in head and neck squamous cell carcinoma

2006 - 2008 プロテオミクスを用いた配偶子形成過程における分子基盤の解析

2007 - 2008 Analysis of gonad developmental mechanisms concerning of a germ cell-specific antigen, TEX101 through gene transfer

2005 - 2007 女性生殖器腫瘍の分子標的抗体

2006 - 2007 Structural and Functional Analysis of glycoproteins participating in the mammalian fertilization and development

2006 - 2007 Mechanisms underlying the role of DNA methylation in fetal programming of adult disease in the neonatal mouse

2006 - 2007 IDENTIFICATION OF TESTICULAR PROTEINS ASSOCIATED WITH THE GERM CELL-SPECIMC PROTEIN, TEX101 : CELLUBREVIN IS INVOLVED IN TEX101-TRAFFICKING TO THE GERM CELL SURFACE DURING SPERMATOGENESIS IN MICE

2004 - 2006 エピジェネティクスからみた生殖補助技術の配偶子・受精卵ゲノムへ の影響解析

2005 - 2006 Prevention for dyslipidemia and obesity based on gender-specific difference in middle-aged women

2004 - 2005 BASIC STUDY FOR EPIGENETIC EFFECT(S) CAUSED BY ASSISTED REPRODUCTIVE TREATMENT ON THE GERM-CELL/ZYGOTE

2002 - 2004 遺伝子改変モデル動物を用いた雌性生殖管の受精時における分子制御機構の解析

2002 - 2003 Functional analysis of neutrophils that infiltrated in the S.mansoni-induced hepatic granuloma

2002 - 2003 Analysis of molecular regulation on female reproductive tract during fertilization using genetic model mice

1999 - 2001 遺伝子改変マウスを用いた卵管特異糖蛋白質生殖生物学的生理活性の解明

1997 - 1999 Inverse PCR法を用いた卵管特異糖蛋白質遺伝子プロモーター領域の解析

1997 - 1998 マストミス体外受精・凍結保存の開発

1997 - 1998 The mouse oviduct-specific glycoprotein gene : Genomic organization and structure of the 5'-flanking regulatory region

1997 - 1997 Invitation Fellowship for Research in Japan

1996 - 1997 PCR法を用いた卵管特異糖蛋白質のゲノムクローニングとその発現機構の解明

1996 - 1997 卵管特異糖タンパク質の生理機能解明(2)

1995 - 1996 In situ ハイブリダイゼーション 法を用いた卵管特異糖蛋白質の発現機構の解明

1995 - 1996 遺伝子相同組み換えを用いた卵管特異糖蛋白質の生殖生理学的活性の解明

1996 - 1996 PCR法を用いた卵管特異糖蛋白質のゲノムクローニングとその発現機構の解明

1995 - 1996 Development of an easy and quick serodiagnostic method for important parasitosis using geratine particles coated with recombinant parasite antigens

1993 - 1996 Mechanism of fertilization and embryo development

1994 - 1995 卵管特異糖タンパク質の生理機能解明

1993 - 1995 分子生物学的アプローチによる哺乳類卵透明帯の構造解析

1995 - 1995 Functional analysis of oviduct-specific glycoproteins in the reproductive system using homologous recombination

1995 - 1995 In situハイブリダイゼーション法を用いた卵管特異糖蛋白質の発現機構の解明

1993 - 1994 分子生物学的アプローチによる哺乳類卵透明帯の構造解析