Rchr
J-GLOBAL ID:201801017171481919   Update date: Feb. 02, 2025

Koike-Kumagai Makiko

Koike-Kumagai Makiko
Research theme for competitive and other funds  (2):
  • 2022 - 2025 血液脳関門を介さない皮膚から脳への新規薬剤輸送機構の解明
  • 2021 - 2024 Elucidation of the cause of phenotypic differences in tuberous sclerosis complex using model mice
Papers (11):
more...
MISC (5):
Lectures and oral presentations  (3):
  • Brain estrogen levels are associated with gender differences in neuropsychiatric symptoms in mouse model of tuberous sclerosis complex, and sirolimus may contribute to symptom alleviation by controlling neurosteroid levels.
    (The 2024 SID Annual Meeting,)
  • Epilepsy and TAND in the tuberous sclerosis complex are caused by an alteration in microglial polarity to M1 and sirolimus cures them by returning microglial polarity to M2.
    (The 2023 International TSC Research Conference,)
  • Sirolimus alters microglial polarity leading to improvement of neuropsychiatric symptoms of tuberous sclerosis complex mice model.
    (1 st. International Conference of Neuroscience and Neurology. Hybrid event in Dubai, UAE 2023)
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