Rchr
J-GLOBAL ID：201801017448218005   Update date: Feb. 01, 2024

Sasaki Takuya

Sasaki Takuya
Affiliation and department：
The University of Tokushima

About The University of Tokushima


Research field  (1)： Cell biology
Research keywords  (3)： 低分子量G蛋白質 ,  細胞骨格制御 ,  細胞内小胞輸送
Research theme for competitive and other funds  (45)：
  • 2021 - 2024 アクチン細胞骨格制御における蛋白質の構造ダイナミクスとdisorder領域の役割
  • 2015 - 2017 A novel therapeutic strategy targeted the conformational plasticity of a single molecule for cancer cell invasion and metastasis
  • 2008 - 2014 Administration of the group grant "Intracellular logistics: interdisciplinary approaches to pathophysiology of membrane traffic"
  • 2008 - 2013 Logistics for the regulation of higher neuronal function
  • 2009 - 2012 Function and mode of action of Rab family small G proteins in the formation of neuronal network
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Papers (147)：
  • Tomohiko Maruo, Kiyohito Mizutani, Muneaki Miyata, Toshihiko Kuriu, Shotaro Sakakibara, Hatena Takahashi, Daichi Kida, Kouki Maesaka, Tsukiko Sugaya, Ayuko Sakane, et al. s-Afadin binds to MAGUIN/Cnksr2 and regulates the localization of the AMPA receptor and glutamatergic synaptic response in hippocampal neurons. The Journal of biological chemistry. 2023. 299. 4. 103040-103040
  • Shotaro Sakakibara, Ayuko Sakane, Takuya Sasaki, Masakazu Shinohara, Tomohiko Maruo, Muneaki Miyata, Kiyohito Mizutani, Yoshimi Takai. Identification of lysophosphatidic acid in serum as a factor that promotes epithelial apical junctional complex organization. The Journal of biological chemistry. 2022. 102426-102426
  • Ayuko Sakane, Taka-Aki Yano, Takayuki Uchihashi, Kazuki Horikawa, Yusuke Hara, Issei Imoto, Shusaku Kurisu, Hiroshi Yamada, Kohji Takei, Takuya Sasaki. JRAB/MICAL-L2 undergoes liquid-liquid phase separation to form tubular recycling endosomes. Communications biology. 2021. 4. 1. 551-551
  • The Mon La, Hiromi Tachibana, Shun-Ai Li, Tadashi Abe, Sayaka Seiriki, Hikaru Nagaoka, Eizo Takashima, Tetsuya Takeda, Daisuke Ogawa, Shin-Ichi Makino, et al. Dynamin 1 is important for microtubule organization and stabilization in glomerular podocytes. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2020. 34. 12. 16449-16463
  • Shotaro Sakakibara, Kiyohito Mizutani, Ayumu Sugiura, Ayuko Sakane, Takuya Sasaki, Shigenobu Yonemura, Yoshimi Takai. Afadin regulates actomyosin organization through αE-catenin at adherens junctions. The Journal of Cell Biology. 2020. 219. 5
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MISC (59)：
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Books (13)：
  • Roles of Rab family small G proteins in formation of the apical junctional complex in epithelial cells.
    Cell Polarity: Biological Role and Basic Mechanisms 2014
  • Rab3A small G protein and its regulators in neurotransmitter release and synaptic plasticity.
    2002
  • Doc2 as a presynaptic modulator for neurotransmitter releas.
    Springer-Verlag Tokyo Inc. 1999
  • The Rho family-Rho GDI system as a temporal and spatial determinant for cytoskeletal control.
    Hokkaido University School of Medicine 1998
  • Rab3A-rabphilin-3A system in neurotransmitter release.
    Lippincott-Raven Publishers, USA 1997
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Lectures and oral presentations  (10)：
  • 1. 屈折率センシング光コムを用いたバイオセンシングに関する検討(4)~新型コロナウイルス(SARS-CoV-2)の検出~
    (第82回応用物理学会秋季学術講演会予稿集 2021)
  • SARS-CoV-2由来RNAの高感度検出に向けたプラズモニックバイオセンサ
    (第68回応用物理学会春季学術講演会予稿集 2021)
  • 1. 多彩な細胞機能を構造生物学から解く-前説も兼ねて
    (第19回日本蛋白質科学会年会・第71回日本細胞生物学会大会 合同年次大会ワークショ ップ 2019)
  • 集団的細胞運動において一分子構造変化が生み出す多様な運動様式とその役割
    (第41回 日本分子生物学会年会 2018)
  • 組織構築・修復過程において1分子構造変化が生み出す多彩な細胞移動とその意義
    (第91回 日本生化学会大会 2018)
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Education (2)：
  • 1991 - 神戸大学大学院医学研究科修了(医博修了)
  • 1985 - 神戸大学医学部卒業
Professional career (1)：
  • 医学博士 (神戸大学)
Work history (9)：
  • 2015/04 - 現在 徳島大学大学院医歯薬学研究部 教授
  • 2004/04 - 2015/03 徳島大学大学院ヘルスパイオサイエンス研究部
  • 2002/04 - 徳島大学教授大学院医学研究科
  • 2000/04 - 徳島大学教授医学部
  • 1998/10 - 大阪大学助教授医学部
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Awards (1)：
  • 1998/10 - 日本癌学会 奨励賞
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