Imamura Toshihiko

イマムラトシヒコ | Imamura Toshihiko

Affiliation and department：

Research field (1)： Fetal medicine/Pediatrics

Research keywords (4)：分子生物学 , 小児血液 , 急性リンパ性白血病 , 小児造血器腫瘍

Research theme for competitive and other funds (7)：

2022 - 2025 The development of CAR-T therapy targeting FLT3 and CD19 for infant acute lymphoblastic leukemia
2021 - 2024 Investigation of leukemogenic mechanism of intractable pediatric leukemia
2019 - 2022 Development of CAR-T cell therapy for KMT2A-rearranged acute lymphoblastic leukemia
2017 - 2020 Mechanistic analysis of drug-resistance in ALL
2011 - 2013 Identification of new therapeutic target for MLL rearranged acute myeloid leukemia

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Papers (235)：

Hirohito Kubota, Hiroo Ueno, Keiji Tasaka, Tomoya Isobe, Satoshi Saida, Itaru Kato, Katsutsugu Umeda, Mitsuteru Hiwatari, Daiichiro Hasegawa, Toshihiko Imamura, et al. RNA-seq-based miRNA signature as an independent predictor of relapse in pediatric B-cell acute lymphoblastic leukemia. Blood Advances. 2023
Akira Nishimura, Kazuaki Yokoyama, Takuya Naruto, Chika Yamagishi, Toshihiko Imamura, Hiroto Nakazono, Shunsuke Kimura, Mieko Ito, Maiko Sagisaka, Yukie Tanaka, et al. Myeloid/natural killer (NK) cell precursor acute leukemia as a distinct leukemia type. Science advances. 2023. 9. 50. eadj4407
Hisashi Ishida, Yuki Arakawa, Daiichiro Hasegawa, Ikuya Usami, Yoshiko Hashii, Yasuyuki Arai, Satoshi Nishiwaki, Dai Keino, Keisuke Kato, Maho Sato, et al. Reduced-intensity allogenic transplantation for children and adolescents with Philadelphia chromosome-positive acute lymphoblastic leukemia. Annals of hematology. 2023
Tomohiko Imai, Kenichi Sakamoto, Tatsuji Hasegawa, Yoko Shioda, Yoshiyuki Tsutsumi, Satoshi Sakaue, Toshihiko Imamura, Akira Morimoto, Tomoko Iehara. Cerebellar peduncle damage in Langerhans cell histiocytosis-associated neurodegenerative disease revealed by diffusion tensor imaging. Neuroradiology. 2023
Mayumi Hangai, Takahisa Kawaguchi, Masatoshi Takagi, Keitaro Matsuo, Soyoung Jeon, Charleston W K Chiang, Andrew T Dewan, Adam J De Smith, Toshihiko Imamura, Yasuhiro Okamoto, et al. Genome-wide assessment of genetic risk loci for childhood acute lymphoblastic leukemia in Japanese patients. Haematologica. 2023

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MISC (216)：

森本哲, 塩田曜子, 坂本謙一, 工藤耕, 今村俊彦, 工藤寿子. ランゲルハンス細胞組織球症における病態解明と治療の展望-Elucidated pathogenesis and therapeutic prospects in Langerhans cell histiocytosis-第83回日本血液学会学術集会 ; Symposium 2 : Molecular Mechanism of Inflammation and Tumor in Histiocytic Disorders. 臨床血液. 2022. 63. 5. 373-382
森谷邦彦, 今村俊彦, 片山紗乙莉, 戒能明, 岡本賢治, 横山能文, 植村優, 北澤宏展, 関水匡大, 平松英文, et al. BFM基盤のプロトコールで治療をした日本人小児急性リンパ性白血病における症候性骨壊死の発症率は欧米人と同時である(Incidence of symptomatic ON in pediatric ALL treated with BFM based protocol is similar to children in western countries). 日本小児科学会雑誌. 2022. 126. 2. 294-294
森本哲, 塩田曜子, 坂本謙一, 工藤耕, 今村俊彦, 工藤寿子. 組織球性症候群における炎症と腫瘍の分子病態解明されてきたLCHの病態と治療の展望(Elucidated pathogenesis and therapeutic prospects in LCH). 日本血液学会学術集会. 2021. 83回. SY2-3
西村聡, 横山和明, 成戸卓也, 中園博仁, 木村俊介, 今村俊彦, 森尾友宏, 金井昭教, 松井啓隆, 梅田雄嗣, et al. 新規の白血病特性を有するmyeloid/natural killer cell precursor acute leukemia(Myeloid/natural killer(NK) cell precursor acute leukemia as a novel distinctive leukemia entity). 日本血液学会学術集会. 2021. 83回. PL-4
三木瑞香, 末延聡一, 長谷川大一郎, 川口浩史, 平松英文, 坂口公祥, 宇佐美郁哉, 今村俊彦, 佐藤篤, 齋藤明子, et al. 小児高リスク急性リンパ性白血病(ALL)に対する寛解導入療法変更による有害事象の軽減効果. 日本小児科学会雑誌. 2021. 125. 2. 310-310

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Education (2)：

1998 - 2002 Kyoto Prefectural University of Medicine Graduate School of Medical Science
1988 - 1994 Kyoto Prefectural University of Medicine

Professional career (1)：

医学博士 (京都府立医科大学)

Work history (9)：

2022/10 - 現在京都府立医科大学大学院医学研究科小児科学准教授
2013/04 - 2022/09 Kyoto Prefectural University of Medicine
2008/07 - 2013/03 Kyoto Prefectural University of Medicine
2006/09 - 2008/06 Kyoto Prefectural University of Medicine
2004/09 - 2006/08 シカゴ大学内科血液腫瘍部門博士研究員

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