Rchr
J-GLOBAL ID：201801017772014021   Update date: Apr. 20, 2024

Hashizume Ryotaro

ハシヅメ リョウタロウ | Hashizume Ryotaro
Affiliation and department：
Mie University

About Mie University


Homepage URL  (1)： http://www.medic.mie-u.ac.jp/organization/course/pathol_matrix/
Research field  (1)： Medical biochemistry
Research keywords  (5)： iPS cell ,  Down syndrome ,  ゲノム医科学 ,  genome editing ,  aneuploidy
Research theme for competitive and other funds  (5)：
  • 2021 - 2025 Establishing the type I CRISPR platform for extra chromosome elimination through epigenetic modulation
  • 2016 - 2019 Proof of concept study of a novel excess chromosome elimination therapy to ameliorate and prevent trisomy 21 associated complications
  • 2016 - 2018 Trisomic rescue induction by allele-specific chromosome breakage using genome editing technique
  • 2014 - 2016 Myocardial regeneration research based on cell-cycle progression of the adult myocyte
  • 2014 - 2015 ゲノム不安定性を示すがん細胞を標的とした抗がんアプローチの確立
Papers (40)：
  • 望木 郁代, 奥川 喜永, 橋詰 令太郎, 今井 裕, 中谷 中, 堀 浩樹. 遺伝カウンセリングを受診する患者とその家族が医療者に期待すること. 日本遺伝カウンセリング学会誌. 2023. 44. 2. 122-122
  • 奥川 喜永, 藤原 拓海, 北嶋 貴仁, 望木 郁代, 橋詰 令太郎, 今井 裕, 戸野 泰隆, 水野 聡朗, 松原 貴子, 問山 裕二. がんゲノム医療リアルワールドデータから考える検査プロセスの自己意思決定支援への重要性. Palliative Care Research. 2023. 18. Suppl. S209-S209
  • Ikuyo Mochiki, Yoshinaga Okugawa, Ryotaro Hashizume, Hiroshi Imai, Makoto Ikejiri, Toru Ogura, Kaname Nakatani, Hiroki Hori. Psychological characteristics of Japanese patients and their family members receiving genetic counseling: A single-institute exploratory study. Journal of Genetic Counseling. 2022. 32. 1. 128-139
  • Yoshinaga Okugawa, Takumi Fujiwara, Takahito Kitajima, Maki Nakamura, Makoto Ikejiri, Takeshi Sasaki, Reiko Yamada, Katsunori Uchida, Ryotaro Hashizume, Hiroshi Imai, et al. P52-5 Effort of Cancer Genome Center Hospital in Rural National University. Annals of Oncology. 2022. 33. S532-S532
  • Sachiko Wakita, Mari Hara, Yasuji Kitabatake, Keiji Kawatani, Hiroki Kurahashi, Ryotaro Hashizume. Experimental method for haplotype phasing across the entire length of chromosome 21 in trisomy 21 cells using a chromosome elimination technique. Journal of human genetics. 2022. 67. 10. 565-572
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MISC (86)：
  • 奥川 喜永, 北嶋 貴仁, 藤原 拓海, 坪井 順哉, 橋詰 令太郎, 今井 裕, 望木 郁代, 中谷 中. 検査に関わる人が知っておきたい"がんゲノム医療". 日本臨床検査医学会誌. 2023. 71. 10. 711-716
  • 奥川 喜永, 藤原 拓海, 北嶋 貴仁, 望木 郁代, 橋詰 令太郎, 今井 裕, 戸野 泰隆, 水野 聡朗, 松原 貴子, 問山 裕二. がんゲノム医療リアルワールドデータから考える検査プロセスの自己意思決定支援への重要性. Palliative Care Research. 2023. 18. Suppl. S209-S209
  • 奥川 喜永, 北嶋 貴仁, 藤原 拓海, 橋詰 令太郎, 今井 裕, 望木 郁代, 中谷 中. 【がんゲノム医療-扉の向こうへ進むための基礎知識-】2次的所見の対応. 癌の臨床. 2022. 66. 5. 331-337
  • 松田 知世, 釘宮 弥里, 金山 和樹, 今井 裕, 小塚 祐司, 橋詰 令太郎, 渡邉 昌俊. EUS-FNAで診断に苦慮したWild type GISTの1例. 日本臨床細胞学会雑誌. 2021. 60. Suppl.1. 272-272
  • Ryuji Okamoto, Itaru Goto, Ryotaro Hashizume, Yoshito Ogihara, Yusuf Ali, Eitaro Fujii, Masaaki Ito. The Renal Papillary Tip Expresses a Substance That Can Stimulate Bnp Production and Secretion From Cardiomyocytes. CIRCULATION. 2018. 138
ｍore...
Patents (1)：
  • A wet-electrospun biodegradable scaffold and uses
Lectures and oral presentations  (6)：
  • Trisomic rescue via allele-specific multiple chromosome cleavages using the CRISPR-Cas9 platform in trisomy 21 cells
    (Human Genetics Asia 2023, Special Interest Group (Genomic and Epigenomic Analysis for Prenatal and Perinatal Disorders) 2023)
  • The challenges towards chromosome therapy to treat aneuploidy conditions
    (The 65th Annual Meeting of the Japan Society of Human Genetics 2020)
  • Proper handling of pathological specimens in the future
    (The 67th Annual Meeting of Japanese Society of Laboratory Medicine 2020)
  • Cancer genomic medicine as a clinical test
    (The 67th Annual Meeting of Japanese Society of Laboratory Medicine 2020)
  • Phasing on the entire length of chromosome by chromosome elimination using genome editing technology in trisomy 21 cells
    (2018)
ｍore...
Education (2)：
  • 2005 - 2012 Nagoya University School of Medicine PhD course
  • 1990 - 1997 Hamamatsu University School of Medicine
Professional career (1)：
  • 博士(医学) (名古屋大学)
Work history (8)：
  • 2021/06 - 現在 三重大学 大学院医学系研究科修復再生病理学 講師
  • 2012/04 - 2021/05 Mie University Department of Pathology and Matrix Biology, Mie University Graduate School of Medicine Assistant Professor
  • 2011/07 - 2012/03 University of Pittsburgh Department of Surgery Research Instructor
  • 2010/10 - 2011/06 University of Pittsburgh Department of Surgery Research Associate
  • 2007/10 - 2010/09 University of Pittsburgh Department of Surgery Post-Doctoral Associate
Show all
Awards (1)：
  • 2012/10 - the International Society for Heart Research Best Poster Presentation Award
Association Membership(s) (6)：
JAPAN SURGICAL SOCIETY ,  Japanese Society of Clinical Cytology ,  THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE ,  JAPANESE SOCIETY OF LABORATORY MEDICINE ,  THE JAPAN SOCIETY OF HUMAN GENETICS ,  THE JAPANESE SOCIETY OF PATHOLOGY
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