J-GLOBAL ID:201801017790246991   Update date: Nov. 23, 2018

OGAWA, Yasuhiro

OGAWA, Yasuhiro
Affiliation and department:
Homepage URL  (1): https://www.my-pharm.ac.jp/
Research field  (1): Neurophysiology/General neuroscience
Research keywords  (2): neurological disorders ,  astrocyte
Papers (22):
  • Ogawa Y, Furusawa E, Saitoh T, Sugimoto H, Omori T, Shimizu S, Kondo H, Yamazaki M, Sakuraba H, Oishi K. Inhibition of astrocytic adenosine receptor A2A attenuates microglial activation in a mouse model of Sandhoff disease. Neurobiology of disease. 2018. 118. 142-154
  • Ogawa Y, Irisa M, Sano T, Yanagi Y, Furusawa E, Saito T, Yamanaka S, Itoh K, Sakuraba H, Oishi K. Improvement in dysmyelination by the inhibition of microglial activation in a mouse model of Sandhoff disease. Neuroreport. 2018. 29. 11. 962-967
  • Ogawa Y, Sano T, Irisa M, Kodama T, Saito T, Furusawa E, Kaizu K, Yanagi Y, Tsukimura T, Togawa T, Yamanaka S, Itoh K, Sakuraba H, Oishi K. FcRγ-dependent immune activation initiates astrogliosis during the asymptomatic phase of Sandhoff disease model mice. Scientific reports. 2017. 7. 40518
  • Ogawa Y, Kaizu K, Yanagi Y, Takada S, Sakuraba H, Oishi K. Abnormal differentiation of Sandhoff disease model mouse-derived multipotent stem cells toward a neural lineage. PloS one. 2017. 12. 6. e0178978
  • Hirono M, Ogawa Y, Misono K, Zollinger DR, Trimmer JS, Rasband MN, Misonou H. BK Channels Localize to the Paranodal Junction and Regulate Action Potentials in Myelinated Axons of Cerebellar Purkinje Cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2015. 35. 18. 7082-7094
Books (2):
  • Clinical Neuroscience vol.23 no. 2
  • Proteomics of the nervous system
    WILEY-VCH Verlag GmbH & Co. 2008
Lectures and oral presentations  (5):
  • ザンドホッフ病モデルマウス由来iPS細胞から神経系細胞を作りました
    (臨床遺伝学公開シンポジウム 2012)
  • ザンドホッフ病モデルマウス脳の早期異常を見つけました
    (臨床遺伝学公開シンポジウム 2014)
  • ザンドホッフ病モデルマウス由来iPS細胞を用いて薬物による治療効果を検討しました
    (臨床遺伝学公開シンポジウム 2015)
  • ザンドホッフ病モデルマウスにおいて、活性化アストロサイトにA2A受容体が発現誘導し、A2A受容体を遮断すると活性化ミクログリアの数が減少することを発見しました
    (臨床遺伝学公開シンポジウム 2017)
  • ザンドホッフ病でのグリア細胞を標的とした治療薬の効果
    (応用薬理シンポジウム 2017)
Education (2):
  • 2001 - 2004 SOKENDAI, the Graduate University for Advanced Studies Graduate School of Biostudies Physiological Science
  • - 現在 Meiji Pharmaceutical University
Work history (4):
  • 2004/04 - 2005/03 National Institutes of Natural Sciences Postdoctoral Researcher
  • 2005/04 - 2007/08 University of Connecticut Health Center Postdoctoral Researcher
  • 2007/08 - 2008/08 Baylor College of Medicine Postdoctoral Researcher
  • 2008/09 - 現在 Meiji Pharmaceutical University Assistant Professor
Awards (1):
  • National multiple sclerosis society Postdoctoral Fellowships The role of cytoskeletal proteins in paranodal axon-glia interactions
Association Membership(s) (1):
Society for Neuroscience
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