Rchr
J-GLOBAL ID：201801017863546930   Update date: Jul. 21, 2024

Mizoguchi Fumitaka

ミゾグチ フミタカ | Mizoguchi Fumitaka
Affiliation and department：
東京医科歯科大学 大学院医歯学総合研究科 医歯学系専攻 生体環境応答学講座 膠原病・リウマチ内科学

About 東京医科歯科大学 大学院医歯学総合研究科 医歯学系専攻 生体環境応答学講座 膠原病・リウマチ内科学


Job title： 講師
Research field  (1)： Allergies and connective tissue disease
Research keywords  (5)： 骨粗鬆症 ,  トランスクリプトミクス ,  線維芽細胞 ,  特発性炎症性筋疾患 ,  関節リウマチ
Research theme for competitive and other funds  (13)：
  • 2019 - 2022 多発性筋炎/皮膚筋炎の筋組織の免疫表現型解析による病態解明と疾患再分類への挑戦
  • 2019 - 2022 Development of new therapeutic strategies targeting rheumatoid arthritis-associated fibroblast subset
  • 2017 - 2020 自己免疫疾患に関する調査研究
  • 2018 - 2019 免疫表現型解析による皮膚筋炎/多発性筋炎の疾患再分類
  • 2016 - 2019 新規線維芽細胞サブセットを標的とした関節リウマチ治療法開発への挑戦
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Papers (60)：
  • Yasuhiro Tagawa, Tetsuya Saito, Hideyuki Iwai, Motohiko Sato, Seiji Noda, Akio Yamamoto, Mineto Ota, Kentaro Endo, Hideyuki Koga, Yasuhiro Takahara, et al. ARID5B is a negative modulator of IL-6 production in rheumatoid arthritis synovial fibroblasts. Immunological medicine. 2024. 1-10
  • Natsuka Umezawa, Fumitaka Mizoguchi, Yasuhiro Maejima, Naoki Kimura, Hisanori Hasegawa, Tadashi Hosoya, Minoru Fujimoto, Hitoshi Kohsaka, Tetsuji Naka, Shinsuke Yasuda. Leucine-rich alpha-2 glycoprotein as a potential biomarker for large vessel vasculitides. Frontiers in Medicine. 2023. 10
  • Mari Kamiya, Fumitaka Mizoguchi, Kimito Kawahata, Dengli Wang, Masahiro Nishibori, Jessica Day, Cynthia Louis, Ian P Wicks, Hitoshi Kohsaka, Shinsuke Yasuda. Targeting necroptosis in muscle fibers ameliorates inflammatory myopathies. Nature communications. 2022. 13. 1. 166-166
  • Akio Yamamoto, Tetsuya Saito, Tadashi Hosoya, Kimito Kawahata, Yoshihide Asano, Shinichi Sato, Fumitaka Mizoguchi, Shinsuke Yasuda, Hitoshi Kohsaka. Therapeutic effect of cyclin-dependent kinase 4/6 inhibitor on dermal fibrosis in murine models of systemic sclerosis. Arthritis & rheumatology (Hoboken, N.J.). 2021. 74. 5. 860-870
  • Tadashi Hosoya, Tetsuya Saito, Hiroyuki Baba, Nao Tanaka, Seiji Noda, Youji Komiya, Yasuhiro Tagawa, Akio Yamamoto, Fumitaka Mizoguchi, Kimito Kawahata, et al. Chondroprotective effects of CDK4/6 inhibition via enhanced ubiquitin-dependent degradation of JUN in synovial fibroblasts. Rheumatology (Oxford, England). 2021. 61. 8. 3427-3438
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MISC (33)：
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Books (11)：
  • リウマチ専門医試験 例題と解説 改訂第9版 日本リウマチ学会編集
    メジカルビュー社 2020
  • Practice of Internal Medicine
    Igaku-Shoin 2020
  • 全身性エリテマトーデス診療ガイドライン 2019
    南山堂 2019 ISBN:9784525234713
  • TODAY'S THERAPY 2019
    2019 ISBN:9784260036504
  • シェーグレン症候群の診断と治療マニュアル改定第3版. 日本シェーグレン症候群研究会編
    診断と治療社 2018 ISBN:9784787823694
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Lectures and oral presentations  (56)：
  • シングルセル解析による 関節リウマチの病態解明
    (第64回日本リウマチ学会総会・学術集会 2020)
  • 関節リウマチ診療の課題克服に向けた 滑膜線維芽細胞研究の新展開
    (九州膠原病ネットワーク学術講演会 2020)
  • Gene Expression Profiling of Synovial Fibroblast Subsets Revealed Novel Transcription Factors Driving Their Pathogenic Functions in Rheumatoid Arthritis
    (Keystone Symposia, Stromal Cells in Immunity and Disease 2020)
  • Gene expression profiling of synovial fibroblast subsets revealed novel transcription factors driving their pathogenic functions in rheumatoid arthritis
    (Keystone Symposia, Stromal Cells in Immunity and Disease 2020)
  • 関節リウマチ関連線維芽細胞サブセットを 標的とした新規治療戦略の開発
    (2019年度AMED合同成果報告会 疾患克服への挑戦2019 2020)
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Education (2)：
  • 2004 - 2008 Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences
  • 1995 - 2001 Tokyo Medical and Dental University Faculty of Medicine
Professional career (1)：
  • 博士(医学)
Work history (7)：
  • 2020/04 - 現在 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Medical and Dental Sciences Bio-Environmental Response Rheumatology Junior Associate Professor
  • 2018/04 - 2020/03 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Medical and Dental Sciences Bio-Environmental Response Rheumatology Assistant Professor
  • 2016/04/01 - 2018/03/31 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Medical and Dental Sciences Bio-Environmental Response Rheumatology Assistant Professor
  • 2012/12 - 2016/03 Brigham and Women's Hospital, Harvard Medical School Devision of Rheumatology, Immunology and Allergy Research Fellow
  • 2008/04/01 - 2015/11/30 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Medical and Dental Sciences Bio-Environmental Response Rheumatology Assistant Professor
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Committee career (12)：
  • 2019/04 - 現在 日本臨床免疫学会 広報・教育・次世代育成委員会委員
  • 2019/04 - 現在 日本臨床免疫学会 学術・認定医委員会委員
  • 2018/05 - 現在 BMC Rheumatology Associate Editor
  • 2018/02 - 現在 The Asia Pacific League of Associations for Rheumatology Scleroderma/Myositis Special Interest Group Member
  • 2018/01 - 現在 日本臨床免疫学会 評議員
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Awards (11)：
  • 2016/09 - Tokyo Medical and Dental University Young Investigator Award
  • 2012/05 - 日本リウマチ財団 平成24年度日本リウマチ財団海外派遣研修医
  • 2011/09 - 39th Annual Meeting of The Japan Society for Clinical Immunology Excellent Abstract Award
  • 2011/07 - 55th Annual Meeting of the Japan College of Rheumatology Poster Award
  • 2010/06 - 3rd International Conference on Osteoimmunology Aegean Conferences. Travel Award
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Association Membership(s) (5)：
JAPANESE SOCIETY FOR BONE AND MINERAL RESEARCH ,  American College of Rheumatology ,  THE JAPAN SOCIETY FOR CLINICAL IMMUNOLOGY ,  THE JAPANESE SOCIETY OF INTERNAL MEDICINE ,  JAPAN COLLEGE OF RHEUMATOLOGY
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