2014 - 2017 Development of nuclear medical imaging probes targeting cerebral amyloid antipathy
Papers (22):
Shimpei Iikuni, Yuya Okada, Yoichi Shimizu, Hiroyuki Watanabe, Masahiro Ono. Synthesis and evaluation of indium-111-labeled imidazothiadiazole sulfonamide derivative for single photon emission computed tomography imaging targeting carbonic anhydrase-IX. Bioorganic and Medicinal Chemistry Letters. 2020. 30. 14. 127255-127255
Hiroyuki Watanabe, Kiyoshiro Kawano, Yoichi Shimizu, Shimpei Iikuni, Yuji Nakamoto, Kaori Togashi, Masahiro Ono. Development of Novel PET Imaging Probes for Detection of Amylin Aggregates in the Pancreas. Molecular Pharmaceutics. 2020. 17. 4. 1293-1299
Hiroyuki Watanabe, Haruka Tatsumi, Sho Kaide, Yoichi Shimizu, Shimpei Iikuni, Masahiro Ono. Structure-Activity Relationships of Radioiodinated 6,5,6-Tricyclic Compounds for the Development of Tau Imaging Probes. ACS Medicinal Chemistry Letters. 2020. 11. 2. 120-126
Hiroyuki Watanabe, Futa Itagaki, Yoichi Shimizu, Shimpei Iikuni, Masahiro Ono. Synthesis and evaluation of a radioiodinated BODIPY derivative as a thiol-labeling agent. Journal of Labelled Compounds and Radiopharmaceuticals. 2019. 62. 13. 885-891
Sho Kaide, Hiroyuki Watanabe, Yoichi Shimizu, Haruka Tatsumi, Shimpei Iikuni, Yuji Nakamoto, Kaori Togashi, Masafumi Ihara, Hideo Saji, Masahiro Ono. 18F-labeled benzimidazopyridine derivatives for PET imaging of tau pathology in Alzheimer's disease. Bioorganic and Medicinal Chemistry. 2019. 27. 16. 3587-3594