Iikuni Shimpei

Affiliation and department：

Research field (1)： Pharmaceuticals - analytical and physicochemistry

Research theme for competitive and other funds (3)：

2019 - 2021 クマリンを基盤とした炭酸脱水酵素IX標的がんセラノスティクス用薬剤の開発
2016 - 2019 診断・治療を融合するTheranostics用多機能低分子キレート医薬品の開発
2014 - 2017 Development of nuclear medical imaging probes targeting cerebral amyloid antipathy

Papers (22)：

Shimpei Iikuni, Yuya Okada, Yoichi Shimizu, Hiroyuki Watanabe, Masahiro Ono. Synthesis and evaluation of indium-111-labeled imidazothiadiazole sulfonamide derivative for single photon emission computed tomography imaging targeting carbonic anhydrase-IX. Bioorganic and Medicinal Chemistry Letters. 2020. 30. 14. 127255-127255
Hiroyuki Watanabe, Kiyoshiro Kawano, Yoichi Shimizu, Shimpei Iikuni, Yuji Nakamoto, Kaori Togashi, Masahiro Ono. Development of Novel PET Imaging Probes for Detection of Amylin Aggregates in the Pancreas. Molecular Pharmaceutics. 2020. 17. 4. 1293-1299
Hiroyuki Watanabe, Haruka Tatsumi, Sho Kaide, Yoichi Shimizu, Shimpei Iikuni, Masahiro Ono. Structure-Activity Relationships of Radioiodinated 6,5,6-Tricyclic Compounds for the Development of Tau Imaging Probes. ACS Medicinal Chemistry Letters. 2020. 11. 2. 120-126
Hiroyuki Watanabe, Futa Itagaki, Yoichi Shimizu, Shimpei Iikuni, Masahiro Ono. Synthesis and evaluation of a radioiodinated BODIPY derivative as a thiol-labeling agent. Journal of Labelled Compounds and Radiopharmaceuticals. 2019. 62. 13. 885-891
Sho Kaide, Hiroyuki Watanabe, Yoichi Shimizu, Haruka Tatsumi, Shimpei Iikuni, Yuji Nakamoto, Kaori Togashi, Masafumi Ihara, Hideo Saji, Masahiro Ono. ¹⁸F-labeled benzimidazopyridine derivatives for PET imaging of tau pathology in Alzheimer's disease. Bioorganic and Medicinal Chemistry. 2019. 27. 16. 3587-3594

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MISC (40)：

飯國慎平, 渡邊裕之, 志水陽一, 小野正博. 炭酸脱水酵素-IX高発現腫瘍イメージングを目的とした99mTc-ヒドロキサムアミド錯体の開発. JSMI Report. 2020. 13. 1. 27-31
垂水勇太, 渡邊裕之, 貝出翔, 飯國慎平, 志水陽一, 小野正博. 新規PET用タウイメージングプローブの開発を目的とした18F標識ベンゾイミダゾピリジン誘導体の合成と評価. 核医学. 2019. 56. Suppl. S151-S151
渡邊裕之, 松下直樹, 志水陽一, 飯國慎平, 小野正博. オレキシン2受容体を標的とした18F標識ジアリールニコチンアミド誘導体の合成と評価. 核医学. 2019. 56. Suppl. S151-S151
貝出翔, 渡邊裕之, 志水陽一, 飯國慎平, 伊東恭子, 小野正博. ヒト剖検脳切片を用いたBIP-NMe2に関する生化学評価. 核医学. 2019. 56. Suppl. S152-S152
飯國慎平, 小野正博. 炭酸脱水酵素IXイメージングプローブとしてのIn-111標識イミダゾチアジアゾールスルホンアミド誘導体の開発(Development of Indium-111-labeled Imidazothiadiazole Sulfonamide Derivative as Carbonic Anhydrase-IX Imaging Probe). 日本癌学会総会記事. 2019. 78回. J-1048

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