Aiba Yuichiro

アイバユウイチロウ | Aiba Yuichiro

Affiliation and department：
Job title： Associate professor

Research field (7)： Molecular biology , Chemical biology , Molecular biochemistry , Biochemistry , Bioorganic chemistry , Functional biochemistry , Applied biochemistry

Research keywords (8)： Nucleic Acid Chemistry, Peptide Nucleic Acid, PNA, Peptide, Protein, Chemical Biology, Genetic Engineering, Protein Engineering, Molecular Biology, Bioorganic Chemistry, Bioinorganic Chemistry , Biofunctional Chemistry , Bioinorganic Chemistry , Bioorganic Chemistry , Molecular Biology , Chemical Biology , Peptide Nucleic Acid , Nucleic Acid Chemistry

Research theme for competitive and other funds (30)：

2022 - 2025 ペプチド核酸(PNA)による細胞内核酸操作技術の開発(独立基盤形成支援追加交付)
2022 - 2025 ペプチド核酸(PNA)による細胞内核酸操作技術の開発
2022 - 2023 ペプチド核酸(PNA)を用いた遺伝子工学技術の開発
2022 - 2023 研究寄付金
2021 - 2023 非翻訳RNA検出技術による創薬プラットフォーム創成事業

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Papers (48)：

Hiroaki Inaba, Yuma Shisaka, Shinya Ariyasu, Erika Sakakibara, Garyo Ueda, Yuichiro Aiba, Nobutaka Shimizu, Hiroshi Sugimoto, Osami Shoji. Heme-substituted protein assembly bridged by synthetic porphyrin: achieving controlled configuration while maintaining rotational freedom. RSC Advances. 2024. 14. 13. 8829-8836
Kodama, Y, Ariyasu, S, Karasawa, M, Aiba, Y, Shoji, O. Highly selective hydroxylation of gaseous alkanes at the terminal position by wild-type CYP153A33. CATALYSIS SCIENCE & TECHNOLOGY. 2023. 13. 21. 6146-6152
Shinya Ariyasu, Kai Yonemura, Chie Kasai, Yuichiro Aiba, Hiroki Onoda, Yuma Shisaka, Hiroshi Sugimoto, Takehiko Tosha, Minoru Kubo, Takashi Kamachi, et al. Catalytic Oxidation of Methane by Wild-Type Cytochrome P450BM3 with Chemically Evolved Decoy Molecules. ACS Catalysis. 2023. 8613-8623
Kazuto Suzuki, Joshua Kyle Stanfield, Keita Omura, Yuma Shisaka, Shinya Ariyasu, Chie Kasai, Yuichiro Aiba, Hiroshi Sugimoto, Osami Shoji. A Compound I Mimic Reveals the Transient Active Species of a Cytochrome P450 Enzyme: Insight into the Stereoselectivity of P450-Catalysed Oxidations. Angewandte Chemie (International ed. in English). 2023. 62. 13. e202215706
Kazuto Suzuki, Joshua Kyle Stanfield, Keita Omura, Yuma Shisaka, Shinya Ariyasu, Chie Kasai, Yuichiro Aiba, Hiroshi Sugimoto, Osami Shoji. A Compound I Mimic Reveals the Transient Active Species of a Cytochrome P450 Enzyme: Insight into the Stereoselectivity of P450-Catalysed Oxidations. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION. 2023

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Books (6)：

Heme-containing proteins: Structures, functions, and engineering.
Oxford: Elsevier 2023 ISBN:9780128231531
酵素機能を化学的にハックする新規手法の開発
触媒年鑑:触媒技術の動向と展望 2021年版・一般社団法人触媒学会 2021
ペプチド核酸と相分離
相分離生物学の全貌, 現代化学増刊46・東京化学同人 2020
シトクロムP450BM3の誤作動状態を利用したガス状アルカンの直接水酸化
日本エネルギー学会機関誌えねるみくす 2020
スーパー制限酵素ARCUTによる新規遺伝子操作法の開発
細胞工学 2007

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Lectures and oral presentations (42)：

酵素の誤作動を利用した物質生産とその改良
(日本科学振興協会年次大会2023 2023)
ペプチド核酸(PNA)を用いた核酸の液-液相分離制御
(第33回バイオ・高分子シンポジウム 2023)
パラレル型PNAを用いたインベージョン手法の開発
(ITbM/GTRコンソーシアム 2023年度第6回総会・第11回ワークショップ 2023)
ペプチド核酸PNAによる2本鎖 DNA 認識技術の開発-化学修飾PNAとParallel型PNAインベージョンについて-
(第7回CeSPI-NUSR合同セミナー 2023)
Mn-PPIXを補因子とした再構成P450BM3によるバイオ触媒の開発
(革新的触媒領域公開成果報告会 2023)

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Education (3)：

2007 - 2010 The University of Tokyo School of Engineering Department of Chemistry and Biotechnology
2005 - 2007 The University of Tokyo School of Engineering Department of Chemistry and Biotechnology
2001 - 2005 The University of Tokyo Faculty of Engineering Department of Chemistry and Biotechnology

Work history (9)：

2021/04 - 現在 Graduate School of Science Division of Material Science Inorganic and Analytical Chemistry Associate Professor
2015/11 - 現在国立研究開発法人理化学研究所研究員
2020/07 - 2021/03 Nagoya University Graduate School of Science Division of Material Science Inorganic and Analytical Chemistry Associate Professor / Lecturer
2015/07 - 2020/06 Nagoya University Graduate School of Science Division of Material Science Inorganic and Analytical Chemistry Assistant Professor
2012/09 - 2015/06 University of Texas, Southwestern Medical Center Department of Pharmacology Researcher

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Committee career (17)：

2023/04 - 現在日本化学会東海支部幹事
2023/11 - 2023/11 第56回酸化反応討論会実行委員会実行委員
2023/10 - 2023/10 第12回化学フロンティア研究会 2023 幹事
2022/12 - 2022/12 10th Asian Biological Inorganic Chemistry Conference local organizing committee
2022/09 - 2022/09 第16回バイオ関連化学シンポジウム実行委員

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Awards (2)：

2012/06 - Research Group on Polymers and Biosciences, The Society of Polymer Science, Japan Presentation Award for Young Scientists of Symposium on Polymers and Biosciences
2012/02 - Inoue Foundation for Science Inoue Research Award for Young Scientists

Association Membership(s) (9)：

Oligonucleotide Therapeutics Society , 日本ケミカルバイオロジー学会 , Society of Biological Inorganic Chemistry , 化学フロンティア研究会 , The Japan Society of Nucleic Acids Chemistry , Forum on Biopolymers Science, SPSJ , Division of Biofunctional Chemistry, The Chemical Society of Japan , The Society of Polymer Science, Japan , The Chemical Society of Japan

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