Research theme for competitive and other funds (19):
2024 - 2027 Development of antifungal drugs that eliminate damage to infected hosts due to fungal cell death
2021 - 2024 Elucidation of the mechanism of persistent infection of Helicobacter pylori by oscillation-expressed sRNA
2019 - 2021 Approaching the darkness of oral Helicobacter pylori: exploratory research on isolation / identification, infection mechanism, and persistent infection regulators
2018 - 2021 Examination of the persistent infection mechanism of Helicobacter pylori by phage lysogenization
2017 - 2018 細菌外膜小胞への選択的物質導入機構の解明
2015 - 2017 Protective function of stomach-ILC2s induction of IgA for bacteria elimination
2013 - 2016 Host-microbe interaction mediated by intestinal M cells
2013 - 2016 ヘリコバクターピロリの病原性因子とワクチンに関する研究
2015 - 2016 ヘリコバクターピロリ新規エフェクターRNAの探索
2013 - 2015 Regulation and reconstruction of acquired memories in human microbiota
2014 - 2015 ピロリ菌関連胃がんの早期診断を目的とした腫瘍マーカーの探索
2014 - 2015 ヘリコバクターピロリ胃粘膜持続炎症の分子基盤と新規ワクチンへの応用
2013 - 2014 細菌由来新規ターゲティング型アジュバント分子モジュールの開発
2012 - 2013 持続感染病原細菌がコントロールする共生成立の分子機構
2011 - 2013 ヘリコバクターピロリ胃粘膜長期感染に必要な宿主・菌体因子の時空間的動態解析
2011 - 2012 宿主応答撹乱を誘導するヘリコバクターピロリ由来ncRNAの同定
2008 - 2010 ヘリコバクターピロリの胃粘膜感染機構と炎症惹起メカニズムの研究
2006 - 2007 ヘリコバクターピロリの胃粘膜感染成立における分子基盤の確立
2005 - 2006 ヘリコバクターピロリの胃粘膜感染機構の解明
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Papers (91):
Naomi Aini, Tomohiro Miyoshi, Kana Nishida, Hitomi Mimuro. Identification of sialyl Lewis A as a potential ligand for the Helicobacter pylori outer membrane protein HopZ. Biochemical and biophysical research communications. 2025. 776. 152181-152181
Li Wang, Yanan Li, Yuxin He, Yuchen Fang, Hitomi Mimuro, Adam C Midgley, Sei Yoshida. Macropinocytosis regulates cytokine expression through Erk signaling in LPS-stimulated macrophages. Cell structure and function. 2025. 50. 1. 103-113
Hidehiko Kikuchi, Kaori Harata, Takefumi Sagara, Harishkumar Madhyastha, Hitomi Mimuro, Futoshi Kuribayashi. Puberulic acid displays remarkable cytotoxicity and strong inhibitory effect on the all-trans retinoic acid-induced superoxide-generating ability in U937 cells. Fundamental Toxicological Sciences. 2024. 11. 5. 243-249
Hidehiko Kikuchi, Kaori Harata, Harishkumar Madhyastha, Hitomi Mimuro, Futoshi Kuribayashi. Aristolochic acid C displays cytotoxic effect and remarkable enhancing effect on the all-trans retinoic acid-induced superoxide-generating ability in U937 cells. Fundamental Toxicological Sciences. 2024. 11. 4. 197-204
Fumio Takizawa, Hisanori Domon, Satoru Hirayama, Toshihito Isono, Karin Sasagawa, Daisuke Yonezawa, Akiomi Ushida, Satomi Tsutsuura, Tomohiro Miyoshi, Hitomi Mimuro, et al. Effective degradation of various bacterial toxins using ozone ultrafine bubble water. PloS one. 2024. 19. 7. e0306998