Taku Saito

2021 - 2024 Tetra-PEG-gelを用いた神経癒着予防および神経修復促進のための技術開発

2020 - 2024 AI-assisted diagnostic system for osteoporosis

2019 - 2024 Establishment of an integrated locomotive science including dynamics of bone-articular cells and regulation by immune system

2021 - 2023 間葉系幹細胞の抗炎症性サブセットの同定と臨床応用を目指した誘導法の開発

2020 - 2023 シングルセル解析技術に立脚した傍脊柱靱帯の構成細胞解析と後縦靭帯骨化症の病態解明

2020 - 2023 Runx2,3による関節軟骨の統合的制御機構の解明

2020 - 2023 関節最表層の制御・維持における、シグナル分子としてのルブリシンの機能解析

2020 - 2023 Molecular mechanisms underlying homeostasis of artiuclar joint

2020 - 2022 Elucidation of articular joint homeostasis regulated by the cellular network in the synovium

2019 - 2022 Runx2,3による関節軟骨の統合的制御機構の解明

2019 - 2022 Molecular mechanisms underlying homeostasis of artiuclar joint by oxygen and two HIFs

2019 - 2022 Mechanism of bone and cartilage proliferation by a novel bone elongation factor FAM111A

2019 - 2022 Regulation of bone remodeling by reactive sulfur species, the novel signal molecules

2018 - 2022 Prg4に立脚した、細胞・分子の多層的アプローチによる関節形成・維持機構の解明

2019 - 2021 Development of induced Drug-Cells for treating Arthritis (DCA) using human ES cells for osteoarthritis

2018 - 2021 Development of bone and cartilage implant using collagen 3D printer

2018 - 2021 Prevention of Adhesion formation of tendon with Oligo-Tetra-PEG gel

2018 - 2021 Molecular Mechanisms of How Mechanical Stress Regulates Inflammation of Locomotive Organs

2017 - 2020 Mechano-sensor TRPV2 is involved in lubricin induction and suppression of ectopic endochondral ossification in articular joints

2017 - 2020 Molecular mechanisms underlying anti-inflammatory and cartilage protective roles of HIF-1alpha

2017 - 2020 Establishment of the protocol for induction and maturation of human induced pluripotent stem cells into meniscus

2017 - 2020 Possible novel therapy of degenerated intervertebral disc by ADAMTS10

2017 - 2020 Regulation of Articular Chondrocyte Differentiation

2017 - 2019 Screening for anti-arthralgic molecules derived from muscle

2016 - 2019 Investigation of cartilage homeostasis and molecular biology by comparison of ankle and knee joint

2016 - 2019 Elucidation of biomechanology of intervertebral disc degenration

2016 - 2019 Function of RSPO2 in progerssion of OPLL

2015 - 2017 Gait analyses of osteoarthritis model mice for joint pain assessment

2014 - 2017 Molecular mechanisms of osteoarthritis regulation by Tace signaling

2014 - 2017 Development of chondrocyte differentiation method from human iPS cells

2013 - 2016 Roles of Runx2 and Runx3 in cartilage degeneration

2013 - 2015 Analyses of mechano-sensing pathways in chondrocytes using cyclic hydroctatic pressure model

2013 - 2015 変形性関節症治療への応用を目指したS100A1、S100Bの機能解析

2012 - 2015 Analyses of Notch signaling pathway in osteoarthritis

2012 - 2014 Function of ZNF449 in chondryocyte and mesenchymal tissues

2011 - 2014 Research of HIF function in pathophysiology and therapeutics of osteoarthritis

2011 - 2012 Establishment of chondrocyte induction from iPS cells using a fluorescent reporter system.

2010 - 2012 脂質代謝調節因子アディポカインによる軟骨代謝調節機構の検討

2010 - 2012 Strategic research for elucidation of molecular pathophysiology and identification of therapeutic target of lumbar spondylosis

2010 - 2011 Development of novel osteoanabolic agents by selective inhibition of Gq signal in osteoblasts

2007 - 2011 The integrated study for molecular backgrounds and therapeutic targets of osteoarthritis : The ROAD project.

2009 - 2010 運動器再生医療を目指した多能性幹細胞から間葉系細胞への分化誘導シグナルの探索

2008 - 2010 Research of transcriptional regulation by HIF2A during chondrocyte generation and differentiation.

2007 - 2009 Where is the cause of Bartter's syndrome in the kidney?

2006 - 2009 Research of the Molecular Network Regulating Endochondral Ossification