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J-GLOBAL ID：201801018829198830   Update date: Jul. 05, 2023

Fuyu Kobirumaki-Shimozawa

コビルマキ フユ | Fuyu Kobirumaki-Shimozawa
Affiliation and department：
東京慈恵会医科大学 細胞生理学講座

About 東京慈恵会医科大学 細胞生理学講座


Job title： 助教
Research field  (3)： Cell biology ,  Clinical pharmacy ,  Physiology
Research keywords  (3)： cardiomyocyte ,  sarcomere dynamics ,  in vivo imaging
Research theme for competitive and other funds  (12)：
  • 2021 - 2024 In vivo ナノ解析による心筋収縮のリズム調節機構の解明
  • 2020 - 2024 Fundamental research on cardiac nanophysiology for clinical application
  • 2018 - 2021 In vivoナノイメージングによる心疾患の病態解析
  • 2018 - 2020 In vivoナノイメージングによる心疾患の病態解析
  • 2018 - 2020 心筋興奮収縮連関のin vivoナノ解析
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Papers (29)：
  • Yoshitaka Tsuboi, Kotaro Oyama, Fuyu Kobirumaki-Shimozawa, Takashi Murayama, Nagomi Kurebayashi, Toshiaki Tachibana, Yoshinobu Manome, Emi Kikuchi, Satoru Noguchi, Takayoshi Inoue, et al. Mice with R2509C-RYR1 mutation exhibit dysfunctional Ca2+ dynamics in primary skeletal myocytes. Journal of General Physiology. 2022. 154. 11
  • Tomohiro Nakanishi, Kotaro Oyama, Hiroyuki Tanaka, Fuyu Kobirumaki-Shimozawa, Shuya Ishii, Takako Terui, Shin’ichi Ishiwata, Norio Fukuda. Effects of omecamtiv mecarbil on the contractile properties of skinned porcine left atrial and ventricular muscles. Frontiers in Physiology. 2022. 13
  • Kotaro Oyama, Vadim Zeeb, Toshiko Yamazawa, Nagomi Kurebayashi, Fuyu Kobirumaki-Shimozawa, Takashi Murayama, Hideto Oyamada, Satoru Noguchi, Takayoshi Inoue, Yukiko U. Inoue, et al. Heat-hypersensitive mutants of ryanodine receptor type 1 revealed by microscopic heating. Proceedings of the National Academy of Sciences. 2022. 119. 32
  • Fuyu Kobirumaki-Shimozawa, Togo Shimozawa, Kotaro Oyama, Shunsuke Baba, Jia Li, Tomohiro Nakanishi, Takako Terui, William Louch, Shin'ichi Ishiwata, Norio Fukuda. Synchrony of sarcomeric movement regulates left ventricular pump function in the in vivo beating mouse heart. The Journal of General Physiology. 2021. 153. 11
  • Fuyu Kobirumaki-Shimozawa, Tomohiro Nakanishi, Togo Shimozawa, Takako Terui, Kotaro Oyama, Jia Li, William Louch, Shin'ichi Ishiwata, Norio Fukuda. Real-time in vivo imaging of mouse left ventricle reveals fluctuating movements of the intercalated discs. Nanomaterials. 2020. 10. 3. E532-532
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MISC (12)：
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Lectures and oral presentations  (21)：
  • Synchrony of sarcomere dynamics in the in vivo beating mouse heart.
    (2023)
  • In vivo cardiac nano-physiology: sarcomere synchronization and ventricular contractility
    (2022)
  • Synchrony of sarcomeric movement regulates left ventricular pump function in the in vivo beating mouse heart.
    (2021)
  • Analysis of cardiac sarcomere dynamics by in vivo nano-imaging.
    (2020)
  • Nano-imaging of individual sarcomere dynamics in the beating mouse heart in vivo.
    (2018)
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Education (3)：
  • 2000 - 2004 Tokyo University of Pharmacy and Life Sciences
  • 1998 - 2000 Tokyo University of Pharmacy and Life Sciences
  • 1994 - 1998 Tokyo University of Pharmacy and Life Sciences
Work history (4)：
  • - 現在 The Jikei University School of Medicine Department of Cell Physiology Research Associate
  • 2009/04 - 2010/03 The University of Tokyo Department of Physics, School of Science Ppostdoctoral fellow
  • 2007/04 - 2009/03 Tokyo Medical University
  • 2004/04 - 2007/03 The University of Tokyo
Awards (2)：
  • 2016 - The Physiological Society of Japan Irisawa HiroshiAya Memorial Young Researcher Award
  • 2014 - Japan Heart Foundation Japan Heart Foundation Hiroshi Irisawa Aya Memorial Research Honors
Association Membership(s) (3)：
Society of Nano Science and Technology ,  THE BIOPHYSICAL SOCIETY OF JAPAN ,  THE PHYSIOLOGICAL SOCIETY OF JAPAN
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