Tohoku University Graduate School of Life Sciences Department of Biomolecular Sciences Division of Biomolecular Chemistry Laboratory of Applied Biological Molecular Science
About Tohoku University Graduate School of Life Sciences Department of Biomolecular Sciences Division of Biomolecular Chemistry Laboratory of Applied Biological Molecular Science
2017 - 2020 Elucidation of a tRNA conversion mechanism of transsulfursome by the structural analysis of quaternary complex
2016 - 2018 構造情報に基づいた機能変換による膜孔形成毒素の会合機構の解明
2015 - 2018 Development of antibodies for crystallization based on anti-peptide antibody to elucidate the functional structure of small bispecific antibodies
2015 - 2018 Structural study of a huge respiratory supermolecule hemocyanin (international collaboration work)(Fostering Joint International Research)
2015 - 2017 A direct structure determination using lectin-carbohydrate complex
2014 - 2017 Structural study of a huge respiratory supermolecule hemocyanin
2014 - 2016 膜孔形成毒素の動的な作用機構の解明
2012 - 2016 Bio-design for interface molecules in nano scale
2012 - 2014 development of preparation of modified tRNA using protein
2010 - 2012 ナノ世界のインターフェイス構築へのタンパク質工学的デザイン学
2009 - 2011 Structural and functional analysis of Uro-adherence factor A(UafA) from Staphylococcus saprophyticus
2009 - 2010 ボツリヌス神経毒素の結晶構造解析と受容体結合様式の特殊性の解明
2006 - 2010 Replication and pathogenesis of plus strand RNA viruses and double strand RNA viruses
2007 - 2008 Characterization of expression and adherent property of staphylococcal surface proteins associated with staphylococcus infectious diseases.
2007 - 2008 Structural and functional analysis of iron uptake related cell-wall anchored protein Isd from Staphylococcus aureus
2005 - 2006 黄色ブドウ球菌の莢膜合成関連蛋白質群の構造解析
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Papers (114):
Jyunna Yoshida, Yuki Kato, Ai Isogawa, Yoshikazu Tanaka, Izumi Kumagai, Ryutaro Asano, Takeshi Nakanishi, Koki Makabe. Construction of bispecific antibodies by specific pairing between the heavy chain and the light chain using removable SpyCatcher/SnoopCatcher units. Journal of biological engineering. 2024. 18. 1. 57-57
Wijak Yospanya, Akari Matsumura, Yukihiro Imasato, Tomoyuki Itou, Yusuke Aoki, Hikaru Nakazawa, Takashi Matsui, Takeshi Yokoyama, Mihoko Ui, Mitsuo Umetsu, et al. Design of Cyborg Proteins by Loop Region Replacement with Oligo(ethylene glycol): Exploring Suitable Mutations for Cyborg Protein Construction Using Machine Learning. Bulletin of the Chemical Society of Japan. 2024
Risa Asano, Miyu Takeuchi, Makoto Nakakido, Sho Ito, Chihiro Aikawa, Takeshi Yokoyama, Akinobu Senoo, Go Ueno, Satoru Nagatoishi, Yoshikazu Tanaka, et al. Characterization of a novel format scFv×VHH single-chain biparatopic antibody against metal binding protein MtsA. Protein science : a publication of the Protein Society. 2024. 33. 6. e5017
Momoka Ookubo, Yuka Tashiro, Kosuke Asano, Yoshiharu Kamei, Yoshikazu Tanaka, Takayuki Honda, Takeshi Yokoyama, Michiyo Honda. "Rich arginine and strong positive charge" antimicrobial protein protamine: From its action on cell membranes to inhibition of bacterial vital functions. Biochimica et biophysica acta. Biomembranes. 2024. 1866. 5. 184323-184323
Junta Tomono, Kosuke Asano, Takuma Chiashi, Masato Suzuki, Masayuki Igarashi, Yoshiaki Takahashi, Yoshikazu Tanaka, Takeshi Yokoyama. Direct visualization of ribosomes in the cell-free system revealed the functional evolution of aminoglycoside. Journal of biochemistry. 2024. 175. 6. 587-598
Chapter 7 Molluscan Hemocyanins in Vertebrate and Invertebrate Respiratory Proteins, Lipoproteins and other Body Fluid Proteins edited by Ulrich Hoeger and J. Robin Harris
2020
Essentialタンパク質科学
2016
環境と微生物の事典
2014
タンパク質結晶の新展開ー新しい育成技術から構造解析・応用研究へー
2008
Lectures and oral presentations (49):
Crystal structure analysis of LanK complexed with landomycinA, a potent antitumor antibiotic
(e-Asia Joint Symposium on “Marine Biodiversity as a Source of New Chemotypes” 2022)
tRNA thiolation by TtuA-TtuB using [4Fe-4S] cluster
(he 12th International Conference on the Biology, Chemistry and Therapeutic Applications of Nitric Oxide 2022)
2012/04 - 2017/03 Hokkaido University Faculty of Advanced Life Science
2008/01 - 2012/03 Hokkaido University
2006/04 - 2008/01 東京大学大学院 新領域創成科学研究科 博士研究員
2004/04 - 2006/03 Hokkaido University
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Committee career (14):
2023/07 - 現在 日本蛋白質科学会 庶務役員
2022/05 - 現在 日本生物物理学会 東北支部 幹事
2022/04 - 現在 自然科学研究機構生命創成探求センター 運営委員会委員
2021 - 現在 日本生物物理学会理事
2020/04 - 現在 R022量子構造生物学委員会 委員
2021/06 - 2023/06 日本蛋白質科学会 会計役員
2020/08 - 2022/07 文部科学省 学術調査官
2020/05 - 2022/04 日本生物物理学会 東北支部長
2019/01 - 2021/03 クライオ電顕ネットワークユーザーグループ幹事代表
2018 - 2019 日本蛋白質科学会 若手育成役員
2016/06 - 2018/06 日本蛋白質科学会 代議員
2016/06 - 2018/06 日本蛋白質科学会 代議員
2015/01 - 2017/12 トキシンシンポジウム 運営委員会委員
2015/01 - 2017/12 トキシンシンポジウム 運営委員会委員
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Association Membership(s) (6):
PROTEIN SCIENCE SOCIETY OF JAPAN
, 毒素シンポジウム
, THE JAPANESE BIOCHEMICAL SOCIETY
, THE BIOPHYSICAL SOCIETY OF JAPAN
, THE CRYSTALLOGRAPHIC SOCIETY OF JAPAN
, JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY