Rchr
J-GLOBAL ID：201801018961917632   Update date: Feb. 01, 2024

Ichihara Masatoshi

Ichihara Masatoshi
Affiliation and department：
Chubu University

About Chubu University


Research field  (5)： Human pathology ,  Cell biology ,  Hematology and oncology ,  Molecular biology ,  Experimental pathology
Research theme for competitive and other funds  (6)：
  • 2016 - 2019 Analysis of signaling of Hexokinase 2 and MAS receptor in the cardiomyopathy overexpressing a set of microRNA
  • 2013 - 2016 Analysis of mechanisms of overexpression of angiotensin converting enzyme and heart failure in transgenic mice of miRNAs
  • 2010 - 2012 Analysis of microRNA function on heart and smooth muscles and itsanti-tumor effect using genetically modified mice
  • 2007 - 2009 Analysis of development and cancer in microRNA transgenic mice
  • 2006 - 2006 mRNAの1次塩基配列と2次構造予測に基づくsiRNA設計アルゴリズムの開発研究
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Papers (95)：
  • Kota Ogawa, Akiko Noda, Jun Ueda, Takehiro Ogata, Rumiko Matsuyama, Yuji Nishizawa, Shanlou Qiao, Satoru Iwata, Morihiro Ito, Yoshitaka Fujihara, et al. Forced expression of miR-143 and -145 in cardiomyocytes induces cardiomyopathy with a reductive redox shift. Cellular & Molecular Biology Letters. 2020. 25. 1
  • Amane Hori, Sayaka Sobue, Ryosuke Kurokawa, Shin-ichi Hirano, Masatoshi Ichihara, Norio Hotta. Two-week continuous supplementation of hydrogenrich water increases peak oxygen uptake during an incremental cycling exercise test in healthy humans: a randomized, single-blinded, placebo-controlled study. MEDICAL GAS RESEARCH. 2020. 10. 4. 163-169
  • Yasutaka Sakurai, Masaaki Ichinoe, Kazuki Yoshida, Yuka Nakazato, Shoji Saito, Masashi Satoh, Norihiro Nakada, Itaru Sanoyama, Atsuko Umezawa, Yoshiko Numata, et al. Inactivation of REV7 enhances chemosensitivity and overcomes acquired chemoresistance in testicular germ cell tumors. Cancer letters. 2020. 489. 100-110
  • Amane Hori, Masatoshi Ichihara, Hayata Kimura, Hisayoshi Ogata, Takaharu Kondo, Norio Hotta. Inhalation of molecular hydrogen increases breath acetone excretion during submaximal exercise: a randomized, single-blinded, placebo-controlled study. MEDICAL GAS RESEARCH. 2020. 10. 3. 96-102
  • Chisato Inoue, Sayaka Sobue, Yoshiyuki Kawamoto, Yuji Nishizawa, Masatoshi Ichihara, Akihiro Abe, Fumihiko Hayakawa, Motoshi Suzuki, Yoshinori Nozawa, Takahsi Murate. Involvement of MCL1, c-myc, and cyclin D2 protein degradation in ponatinib-induced cytotoxicity against T315I(+) Ph+leukemia cells. Biochemical and biophysical research communications. 2020. 525. 4. 1074-1080
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MISC (12)：
  • 喬 善楼, 加藤 智也, 小澄 璃奈, 川本 善之, 武田 湖州恵, 市原 正智, 岩本 隆司. 低酸素環境におけるRET変異体の機能解析. 生命科学系学会合同年次大会. 2017. 2017年度. [1P-0600]
  • 井上 千聖, 祖父江 沙矢加, 青山 友佳, 水谷 直貴, 川本 善之, 市原 正智, 鈴木 元, 野澤 義則, 安部 明弘, 早川 文彦, et al. BCL2とJNK経路はPh1陽性ALLの良い治療標的となる. 生命科学系学会合同年次大会. 2017. 2017年度. [1P-1022]
  • 祖父江 沙矢加, 市原 正智. Molecular hydrogen alter gene expressions in mouse liver. 生命健康科学研究所紀要. 2016. 12. 38-41
  • 市原 正智, 祖父江 沙矢加, 望月 利晃, 大桑 哲男. 新規メディカルガスの抗酸化・酸化ストレス耐性作用の分子メカニズム 水素による遺伝子発現変化. 日本生理学雑誌. 2013. 75. 6. 54-54
  • 市原正智, 祖父江沙矢加, 大桑哲男, 大野欽司. 分子状水素の生体作用-過去6年間で何が明らかとなったか-. 安定同位体と生体ガス 医学応用. 2013. 5. 1. 4-16
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Lectures and oral presentations  (7)：
  • Mitochondrial unfolded protein response (mtUPR) の誘導を介した水素の生体保護作用の解析
    (第92回日本生化学会大会 2019)
  • Molecular hydrogen activates the mitochondrial unfolded protein response via epigenetic histone modification and ameliorates ultraviolet light-induced damage in Caenorhabditis elegans
    (8th World Congress on Targeting Mitochondria 2017 2017)
  • 水素医学の最近の進歩
    (第6回日本分子状水素医学生物学会大会 2016)
  • Molecular hydrogen is a novel antioxidant to reduce oxidative stress and attenuate disease progression through modification of cell signaling and gene expressions.
    (15th International Conference on Oxidative Stress Reduction, Redox Homeostasis &Antioxidants 2015)
  • Molecular hydrogen influences gene expression profiles of rodent organs in healthy and diseased states
    (JOURNAL OF PHYSIOLOGICAL SCIENCES 2013)
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Professional career (1)：
  • 医学博士 (名古屋大学)
Association Membership(s) (6)：
The Japanese Society for Medical and Biological Research on Molecular Hydrogen ,  THE JAPANESE CANCER ASSOCIATION ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE JAPANESE SOCIETY OF PATHOLOGY ,  THE JAPANESE SOCIETY OF HEMATOLOGY ,  THE JAPANESE SOCIETY OF INTERNAL MEDICINE
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