Rchr
J-GLOBAL ID：201801018974033504
Update date: Sep. 26, 2024
Tanaka Hikaru
Tanaka Hikaru
Affiliation and department：
Job title：
Professor
Research field (1)：
Pharmacology
Research theme for competitive and other funds (15)：
- 2020 - 2023 肺静脈心筋の電気活動を選択的に抑制する薬理学的機序の解明
- 2015 - 2018 Mechanisms for the manifestation of intracellular calcium dependent automaticity in the pulmonary-vein myocardium
- 2013 - 2017 Three dimensional imaging for the investigation of the mechanisms of generation and propagation of automaticity in the pulmonary vein myocardium
- 2012 - 2015 Mechanisms for the intracellular calcium dependent automaticity in the pulmonary-vein myocardium
- 2010 - 2012 Spatio-temporal analysis of intracellularcalcium oscillation in the pulmonary vein myocardium
- 2009 - 2011 The role of intracellular calcium and sodium-calcium exchanger in the automaticity of pulmonary vein myocardium.
- 2008 - 2009 Fluorescence imaging analysis of Na^+/Ca^<2+> exchanger dynamics in myocardial ischemia reperfusion injury
- 2006 - 2007 Studies on the role of Ttype calcium channels in the cardiovascular system using a specific inhibitor
- 2003 - 2004 Novel Pharmacological Protiles of Dihydropyridines
- 1999 - 2000 Studies on the regulation of myocardial SR calcium release channel under in situ environment
- 1996 - 1996 高速走査型共焦点レーザー顕微鏡と蛍光プローブの局在を用いた心筋細胞内Ca動態の研究
- 1994 - 1994 共焦点レーザー走査顕微鏡を用いた心筋細胞内カルシウムイオンの画像化
- 1993 - 1993 筋ジストロフィー症モデルマウス心血管系の電気生理学的、薬理学的異常に関する研究
- 1992 - 1992 筋ジストロフィー症モデルマウス心筋細胞の電気生理学的・薬理学的異常に関する研究
- 1990 - 1992 Studies of dystrophin and its associated proteins
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Papers (207)：
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Shogo Hamaguchi, Naoki Agata, Maika Seki, Iyuki Namekata, Hikaru Tanaka. Developmental Changes in the Excitation-Contraction Mechanisms of the Ventricular Myocardium and Their Sympathetic Regulation in Small Experimental Animals. Journal of Cardiovascular Development and Disease. 2024. 11. 9. 267-267
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Taro Saito, Mahiru Suzuki, Aiko Ohba, Shogo Hamaguchi, Iyuki Namekata, Hikaru Tanaka. Enhanced Late INa Induces Intracellular Ion Disturbances and Automatic Activity in the Guinea Pig Pulmonary Vein Cardiomyocytes. International Journal of Molecular Sciences. 2024. 25. 16. 8688-8688
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Iyuki Namekata, Miku Tamura, Jyunya Kase, Shogo Hamaguchi, Hikaru Tanaka. Cardioprotective Effect against Ischemia-Reperfusion Injury of PAK-200, a Dihydropyridine Analog with an Inhibitory Effect on Cl- but Not Ca2+ Current. Biomolecules. 2023. 13. 12. 1719-1719
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Shogo Hamaguchi, Ikue Morinou, Yuko Shiseki, Ayako Mikami, Maika Seki, Iyuki Namekata, Hikaru Tanaka. Mechanisms for the α-Adrenoceptor-Mediated Positive Inotropy in Mouse Ventricular Myocardium: Enhancing Effect of Action Potential Prolongation. International Journal of Molecular Sciences. 2023. 24. 4. 3926-3926
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Haruhito Hiiro, Kentaro Otsuka, Shogo Hamaguchi, Iyuki Namekata, Hikaru Tanaka. Negative Chronotropic Effects of Class I Antiarrhythmic Drugs on Guinea Pig Right Atria: Correlation with L-Type Ca2+ Channel Blockade. J. 2023. 6. 1. 104-114
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MISC (116)：
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Mikami Yoshinori, Ito Masanori, Hamaguchi Shogo, Murakami Shingo, Tomida Taichiro, Ohshima Daisuke, Namekata Iyuki, Tanaka Hikaru, Adachi-Akahane Satomi. インスリンシグナル伝達障害は糖尿病性心筋症における拡張機能障害の原因となる(Insulin signaling deficiency is responsible for diastolic dysfunction of diabetic cardiomyopathy). The Journal of Physiological Sciences. 2019. 69. Suppl.1. S109-S109
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Mikami Yoshinori, Ito Masanori, Hamaguchi Shogo, Murakami Shingo, Tomida Taichiro, Namekata Iyuki, Tanaka Hikaru, Adachi-Akahane Satomi. 糖尿病マウス心臓におけるSR Ca2+取り込み低下(Defective SR Ca2+ uptake in the heart of diabetic mouse). The Journal of Physiological Sciences. 2018. 68. Suppl.1. S89-S89
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金江春奈, 浜口正悟, 菅沼万貴, 伊藤雅方, 杉本結衣, 三上義礼, 冨田太一郎, 村上慎吾, 赤羽悟美, 行方衣由紀, et al. Streptozotocin誘発糖尿病マウス心室筋における心筋弛緩機能不全に対する薬理学的検討. 日本薬理学雑誌. 2018. 152. Supplement
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Haruna Kanae, Masato Tsuruta, Rieko Horii, Masayuki Omori, Shogo Hamaguchi, Iyuki Namekata, Hikaru Tanaka. Pharmacological investigation of the mouse pulmonary vein spontaneous activity. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2017. 133. 3. S165-S165
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Yusuke Tanaka, Masahiko Irie, Shogo Hamaguchi, Iyuki Namekata, Hikaru Tanaka. Gq-coupled receptor stimulation enhances spontaneous electrical activity of the guinea-pig pulmonary vein myocardium. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2017. 133. 3. S193-S193
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