Rchr
J-GLOBAL ID：201801019018223903
Update date: Apr. 26, 2024
UEHARA IKUNO
ウエハラ イクノ | UEHARA IKUNO
Affiliation and department：
Job title：
Assistant Professor
Research theme for competitive and other funds (3)：
- 2022 - 2025 Analysis of tumor suppression mechanism by antiparasitic drug Ivermectin targeting cancer stem cells
- 2019 - 2022 The role of cGAS-STING pathway in cancer maintenance and metastasis
- 2005 - 2009 Analysis of the gene transcriptional network system regulated by nuclear tumor suppressive factors
Papers (9)：
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Yusuke Motoji, Ryuji Fukazawa, Ryosuke Matsui, Yoshinori Abe, Ikuno Uehara, Makoto Watanabe, Yoshiaki Hashimoto, Yasuo Miyagi, Noriko Nagi-Miura, Nobuyuki Tanaka, et al. Statins Show Anti-Atherosclerotic Effects by Improving Endothelial Cell Function in a Kawasaki Disease-Like Vasculitis Mouse Model. International Journal of Molecular Sciences. 2022. 23. 24. 16108-16108
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Ikuno Uehara, Mitsuko Kajita, Atsuko Tanimura, Shigeaki Hida, Munehiko Onda, Zenya Naito, Shinsuke Taki, Nobuyuki Tanaka. 2-Deoxy-d-glucose induces deglycosylation of proinflammatory cytokine receptors and strongly reduces immunological responses in mouse models of inflammation. Pharmacology research & perspectives. 2022. 10. 2. e00940
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Yushi Hayashi, Hidenori Suzuki, Wataru Nakajima, Ikuno Uehara, Atsuko Tanimura, Toshiki Himeda, Satoshi Koike, Tatsuya Katsuno, Shin-Ichiro Kitajiri, Naoto Koyanagi, et al. Virus-infection in cochlear supporting cells induces audiosensory receptor hair cell death by TRAIL-induced necroptosis. PloS one. 2021. 16. 11. e0260443
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Yushi Hayashi, Hidenori Suzuki, Wataru Nakajima, Ikuno Uehara, Atsuko Tanimura, Toshiki Himeda, Satoshi Koike, Tatsuya Katsuno, Shin-Ichiro Kitajiri, Naoto Koyanagi, et al. Cochlear supporting cells function as macrophage-like cells and protect audiosensory receptor hair cells from pathogens. Scientific reports. 2020. 10. 1. 6740-6740
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Katsuhiko Itoh, Takahiro Ebata, Hiroaki Hirata, Takeru Torii, Wataru Sugimoto, Keigo Onodera, Wataru Nakajima, Ikuno Uehara, Daisuke Okuzaki, Shota Yamauchi, et al. DMPK is a New Candidate Mediator of Tumor Suppressor p53-Dependent Cell Death. Molecules (Basel, Switzerland). 2019. 24. 17
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MISC (34)：
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取井猛流, 杉本亘, 伊藤功彦, 木下菜月, 月生雅也, 後藤俊志, 上原郁野, 中嶋亘, BUDIRAHARDJA Yemima, 三好大輔, et al. Elucidation of the mechanism of nuclear actin filament formation by anti-tumor drug and its regulation. 日本分子生物学会年会プログラム・要旨集(Web). 2023. 46th
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上原郁野, 梶田満子, 田中信之. Effect of Ivermectin as an inhibitor of cancer stem-like cells. 日本分子生物学会年会プログラム・要旨集(Web). 2021. 44th
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取井猛流, 江畑貴弘, 伊藤功彦, 平田宏聡, 杉本渉, 小野寺恵吾, 中嶋亘, 上原郁野, 奥崎大介, 山内翔太, et al. DMPKの新たな発現機構の解明. 日本分子生物学会年会プログラム・要旨集(Web). 2020. 43rd
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上原郁野, 田中信之. Role of type I interferon induced by cGAS-STING pathway in cancer stem cell mentainance. 日本癌学会学術総会抄録集(Web). 2020. 79th
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上原郁野, 田中信之. 2-Deoxy-d-Glucose is a candidate therapeutic agent for inflammation-associated cancer. 日本癌学会学術総会抄録集(Web). 2019. 78th
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Patents (2)：
Professional career (2)：
- Doctor of Medical Science (Nippon Medical School)
- Master of Agriculture (Tohoku University)
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