Research keywords (4):
免疫グロブリン遺伝子再構成
, B細胞分化
, 自己免疫疾患
, エピジェネティクス
Research theme for competitive and other funds (9):
2019 - 2022 うがい液試料の統合的マルチオミクス解析に基づく口腔癌プレシジョン治療の実現
2018 - 2021 免疫グロブリン遺伝子再構成・転写異常によるSLE発症機構の解明
2016 - 2018 自己免疫疾患の免疫グロブリン再構成におけるエピジェネティクス機構の解明
2015 - 2018 うがい液からのDNAメチル化異常検出による口腔癌発癌予測システムの開発
2013 - 2015 不活性化X染色体におけるEscape genes発現制御機構の解明
2009 - 2011 エピジェネティクスによるムチン抗原遺伝子発現機構の解明
2009 - 2011 Expression of MUC1 splicing variants and its relationship with clinicopathological factors in oral squamous cell carcinoma.
2006 - 2007 ヒト病理材料を用いたMUC2ムチン遺伝子発現制御機構の研究
2004 - 2005 ヒト癌におけるムチン遺伝子の発現機構の解明
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Papers (35):
Takuya Hiratsuka, Yoshiki Arakawa, Yuka Yajima, Yu Kakimoto, Keisuke Shima, Yuzo Yamazaki, Masahiro Ikegami, Takushi Yamamoto, Hideshi Fujiwake, Koichi Fujimoto, et al. Hierarchical Cluster and Region of Interest Analyses Based on Mass Spectrometry Imaging of Human Brain Tumours. Scientific reports. 2020. 10. 1. 5757-5757
Tatsuaki Tsuruyama, Norishige Yamada, Shuichiro Ogawa. Basic research and clinical examination of tumor virus. IntechOpen. 2019. inpress
Minghui Yue, Akiyo Ogawa, Norishige Yamada, John Lalith Charles Richard, Artem Barski, Yuya Ogawa. Xist RNA repeat E is essential for ASH2L recruitment to the inactive X and regulates histone modifications and escape gene expression. PLOS GENETICS. 2017. 13. 7. e1006890
T. Tsuruyama, T. Hiratsuka, N. Yamada. Hotspots of MLV integration in the hematopoietic tumor genome. ONCOGENE. 2017. 36. 9. 1169-1175
Mildred Felder, Arvinder Kapur, Ryan Serbin, San Zheng, May Xiong, Norishige Yamada, Manish Patankar. Regulating MUC16 expression to decrease ovarian tumor proliferation and increase efficacy of therapeutic antibodies. CLINICAL CANCER RESEARCH. 2016. 22