MIYAMOTO Takafumi

ミヤモトタカフミ | MIYAMOTO Takafumi

Affiliation and department：
Job title： Assistant Professor
Homepage URL (1)： https://www.ice-fumilab.com

Research field (1)： Cell biology

Research keywords (3)： integrated Cell Engineering , Personalized Nutrition , Synthetic Biology

Research theme for competitive and other funds (19)：

2022 - 2027 アルギニンコードに基づいたがん抑制メカニズムの理解と制御
2023 - 2026 Regulation of insulin-like activities using signaling complexes formed by RNA and IRS-1
2022 - 2026 Integrated analysis for mitochondrial morphology
2022 - 2025 Fatty acid diversity and its sensing mechanism for metabolic control and therapeutic application
2020 - 2025 自然資本主義社会モデルを基盤とする次世代型食料供給産業の創出

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Papers (61)：

Ryosuke Okino, Kazuaki Mukai, Shunpei Oguri, Masato Masuda, Satoshi Watanabe, Yosuke Yoneyama, Sumine Nagaosa, Takafumi Miyamoto, Atsushi Mochizuki, Shin-Ichiro Takahashi, et al. IGF-I concentration determines cell fate by converting signaling dynamics as a bifurcation parameter in L6 myoblasts. Scientific reports. 2024. 14. 1. 20699-20699
Sari, LN, 宮本崇史, 戒能賢太, 小野寺尚子, 狩野真由子, 増田正人, 田村善昭, 林雄介, 山本雄介, 髙橋伸一郎, et al. Label-free imaging of cellular organization in living mammalian cells via external apodization phase-contrast microscopy. Biorxiv. 2024
Y, Furuta, Y, Osaki, Y, Nakagawa, SI, Han, M, Araki, A, Shikama, N, Ohuchi, D, Yamazaki, E, Matsuda, S, Nohara, et al. Genetic and Functional Analyses of Patients with Marked Hypo-High-Density Lipoprotein Cholesterolemia. JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS. 2024. Epub
Song-Iee Han, Masanori Nakakuki, Yoshimi Nakagawa, Yunong Wang, Masaya Araki, Yuta Yamamoto, Hiroaki Tokiwa, Hiroyuki Takeda, Yuhei Mizunoe, Kaori Motomura, et al. Rhomboid protease RHBDL4/RHBDD1 cleaves SREBP-1c at endoplasmic reticulum monitoring and regulating fatty acids. PNAS nexus. 2023. 2. 11. pgad351
Kaori Motomura, Takashi Matsuzaka, Shigeyuki Shichino, Tatsuro Ogawa, Hao Pan, Takuya Nakajima, Yasuhito Asano, Toshitsugu Okayama, Tomoyo Takeuchi, Hiroshi Ohno, et al. Single-cell transcriptome profiling of pancreatic islets from early diabetic mice identifies Anxa10 for Ca2+ allostasis toward β-cell failure. Diabetes. 2023

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MISC (6)：

井上幸江, 伊豫田拓也, 沖田直之, 縄田望月, 松本芽衣, 宮本崇史, 辻大輔, 赤木玲子. Induced expression of heme oxygenase-1, an antioxidant enzyme, associated with cell differentiation of myeloid cell line (HL-60). 日本分子生物学会年会プログラム・要旨集(Web). 2023. 46th
赤木玲子, 久保貴紀, 羽鳥勇太, 宮本崇史, 井上幸江. ラットHeme oxygenase-1の熱ショック応答 HSF1、NRF2、BACH1による転写調節. 日本生化学会大会プログラム・講演要旨集. 2021. 94回. [P-509]
本村香織, 松坂賢, 大野博, 宮本崇史, 関谷元博, 中川嘉, 島野仁. 膵β細胞の増殖を誘導する脂肪酸の探索とその分子機構の解析. 日本臨床分子医学会学術総会プログラム・抄録集. 2019. 56回. 64-64
志村拓哉, 松坂賢, 大野博, 本村香織, 宮本崇史, 関谷元博, 中川嘉, 矢作直也, 島野仁. 脂肪酸伸長酵素Elovl6の嗅覚機能における役割. 日本臨床分子医学会学術総会プログラム・抄録集. 2018. 55回. 74-74
中村康之, 尾野雅哉, 宮本崇史, 喜多村憲章, 加美野宏樹, 吉田将紀, 村井竜也, 齋藤有理, 佐野仁哉, 山田哲司, et al. Mieap結合タンパクとしての14-3-3γの同定とそのミトコンドリア品質管理における役割について(Identification of 14-3-3 gamma as a Mieap-interacting protein and its role in mitochondrial quality control). 日本癌学会総会記事. 2012. 71回. 259-259

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Books (2)：

食品機能性脂質の基礎と応用
シーエムシー出版 2018 ISBN:9784781313313
AMP-activated protein kinase phosphorylates Golgi-specific brefeldin A resistance factor 1 at Thr1337 to induce disassembly of Golgi apparatus.
2008

Lectures and oral presentations (38)：

Comprehensive Understanding of Nutritional signals for Personalized Nutrition
(International Symposium on Signals for Human, Animal and Planetary Health 2024)
Personalized Nutritionの実現に向けた学術・技術基盤の構築
(第2回GTPハッカソン 2023)
Visualization of Cellular Organization with External Apodized Phase Contrast Microscopy (ExAPC)
(The 46th Annual Meeting of the Molecular Biology Society of Japan)
Personalized Nutritionの実現に向けた学術・技術基盤の構築
(ムーンショット型研究開発事業合同セミナー)
プロテオーム解析が切り拓く合成生物学の未来
(日本プロテオーム学会2023年大会 2023)

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Education (3)：

2004 - 2008 Kobe University Graduate School of Medicine Faculty of Medical Sciences
2002 - 2004 Okayama Prefectural University Graduate School of Health and Welfare Course of Nutritional Science
1998 - 2002 Okayama Prefectural University Health and Welfare Science Department of Nutritional Science

Work history (6)：

2018/01 - 現在 University of Tsukuba Department of Internal Medicine (Endocrinology and Metabolism) Assistant Professor
2017/04 - 2017/12 東京大学大学院クリニカルシークエンス分野特任助教
2014/12 - 2017/03 The University of Tokyo The Institute of Medical Science
2014/09 - 2014/11 The University of Tokyo The Institute of Medical Science
2011/04 - 2014/08 Johns Hopkins University Cell Biology Postdoctoral Fellow (Apr2011 - Mar2013)

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Awards (3)：

2020/12 - University of Tsukuba Tsukuba Top Runner
2018/01 - 卓越研究員(文部科学省事業)
2013/04 - Johns Hopkins University The Albert L. Lehninger Award

Association Membership(s) (2)：

The Japanese Cancer Association , The Molecular Biology Society of Japan

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