Rchr
J-GLOBAL ID：201801019570926382   Update date: Apr. 02, 2026

Arai Satoko

新井 郷子 | Arai Satoko
Affiliation and department：
The University of Tokyo Graduate School of Agricultural and Life Sciences, Department of Applied Biological Chemistry

About The University of Tokyo Graduate School of Agricultural and Life Sciences, Department of Applied Biological Chemistry


Job title： Professor
Research field  (3)： Immunology ,  Food sciences ,  Pathobiochemistry
Research keywords  (8)： CD5L ,  Apoptosis Inhibitor of Macrophage (AIM) ,  Cerebrospinal fluid circulation ,  Immunoglobulin M (IgM) ,  Macrophage ,  tissue repair ,  炎症収束学 ,  食の生体記憶
Research theme for competitive and other funds  (21)：
  • 2026 - 2026 A novel host-protective strategy against viral infection: coordinated regulation of infected cell clearance and tissue repair
  • 2023 - 2026 Elucidation of mechanisms for enhancement of host defense response in severe pulmonary infection
  • 2023 - 2026 重症肺感染症における宿主防御応答向上のメカニズム解明
  • 2021 - 2024 Elucidation of the roles of restorative macrophages in inflammatory tissue resilience
  • 2021 - 2024 炎症性組織レジリエンスと組織障害エントロピーの統合的理解と炎症収束学の創成
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Papers (61)：
  • Tetsushi Tezuka, Hiroyuki Arakawa, Kai Kudo, Hideyuki Takehara, Masanobu Morioka, Kazutaka Ikeda, Takashi Ikeda, Keisuke Yasuda, Yuko Fujima, Motoo Kobayashi, et al. A clinical impact of apoptosis inhibitor of macrophage on feline chronic kidney disease. Veterinary journal (London, England : 1997). 2026. 315. 106545-106545
  • Keisuke Yasuda, Akemi Nishijima, Tomoko Inoue, Toshio Takagi, Kazunari Tanabe, Jun Minakuchi, Satoko Arai, Toru Miyazaki. Release of apoptosis inhibitor of macrophage (AIM) from pentameric IgM in serum predicts prognosis after hemodialysis initiation. Communications medicine. 2025. 5. 1. 15-15
  • Chiaki Kajiwara, Ayako Shiozawa, Satoko Arai, Tetsuo Yamaguchi, Sohei Harada, Toru Miyazaki, Kazuhiro Tateda. Apoptosis inhibitor of macrophage suppress immune responses via IL-10 production and delay bacterial clearance in Mycobacterium avium infection. Frontiers in cellular and infection microbiology. 2025. 15. 1578082-1578082
  • Qu Chen, Kazuhiro Ishii, Haruka Mori, Akemi Nishijima, Satoko Arai, Toru Miyazaki, Peter B. Rosenthal. Cryo-EM reveals structural basis for human AIM/CD5L recognition of polymeric immunoglobulin M. Nature Communications. 2024
  • Keisuke Yasuda, Shieri Shimodan, Natsumi Maehara, Aika Hirota, Ruka Iijima, Akemi Nishijima, Haruka Mori, Ran Toyama, Atsumi Ito, Yuri Yoshikawa, et al. AIM/CD5L ameliorates autoimmune arthritis by promoting removal of inflammatory DAMPs at the lesions. Journal of autoimmunity. 2023. 142. 103149-103149
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MISC (43)：
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Lectures and oral presentations  (32)：
  • Virus-induced host factor reprograms innate immunity to enable concurrent viral clearance and tissue repair during acute influenza infection
    (The 54th Annual Meeting for the Japanese Society for Immunology 2025)
  • Coordinated control of infected-cell clearance and tissue repair by host immune modulator in viral infection
    (The 48th Annual Meeting of the Molecular Biology Society of Japan, Symposium Challenges of Experimental Virology to Prepare for the “Next Pandemic” 2025)
  • Overnutrition-Induced “Self as Non-Self”: Insights from a Primordial Immune Sensor
    (The 98th Annual Meeting of the Japan Biochemical Society, Symposium "The Blessing and Curse of Food: Diet-Driven Pathophysiology in Modern Society" 2025)
  • CD5L as a noncanonical PRR: SRCR-mediated recognition of altered self and dynamic ligand gating in modern inflammatory contexts
    (2nd Symposium Immunology of Pattern Recognition Receptors 2025)
  • Structural insights into the IgM-CD5L complex and its impact on resolution of inflammation through DAMPs recognition
    (The 53rd Annual Meeting of the Japan Society for Immunology 2024)
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Education (4)：
  • 2001 - 2004 The University of Tokyo Graduate School of Agricultural and Life Sciences Applied Biological Chemistry
  • 1999 - 2001 The University of Tokyo Graduate School of Agricultural and Life Sciences Applied Biological Chemistry
  • 1997 - 1999 The University of Tokyo
  • 1995 - 1997 The University of Tokyo College of Arts and Sciences
Work history (9)：
  • 2026/04 - 現在 The University of Tokyo Graduate School of Agricultural and Life Sciences, Department of Applied Biological Chemistry Professor
  • 2023/04 - 2026/03 The Insitute for AIM Medicine Department of Molecular Biomedicine for Pathogenesis Chief Scientist, Vice Director
  • 2016/01 - 2023/03 The University of Tokyo Graduate School of Medicine Center for Disease Biology and Integrative Medicine Associate Professor
  • 2014/07 - 2016/01 The University of Tokyo Graduate School of Medicine Center for Disease Biology and Integrative Medicine Project Associate Professor
  • 2007/07 - 2014/07 The University of Tokyo Graduate School of Medicine Center for Disease Biology and Integrative Medicine Lecturer
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Awards (3)：
  • 2026/01 - The 54th Annual Meeting of the Japanese Society for Immunology Best presentation award
  • 2007/08 - 第16回日本アポトーシス学術集会 第3回奨励賞
  • 2005 - University of Texas Southwestern Medical Center, Center for Immunology Best presentation award
Association Membership(s) (6)：
The Japanese Biochemical Society ,  Japan Society for Immunology ,  The Molecular Biology Society Japan ,  The Biomedical Society for Stress Response, Japan ,  日本農芸化学会 ,  Japan Neuroscience Society
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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