Rchr
J-GLOBAL ID：201801019978434100   Update date: Apr. 11, 2024

Okuda Hiroaki

オクダ ヒロアキ | Okuda Hiroaki
Affiliation and department：
Osaka Medical and Pharmaceutical University

About Osaka Medical and Pharmaceutical University


Research field  (3)： Neuropathology ,  Neuroanatomy and physiology ,  Anatomy
Research keywords  (4)： 疼痛学 ,  グリア細胞 ,  神経化学 ,  解剖学
Research theme for competitive and other funds  (22)：
  • 2024 - 2027 赤ビート成分ベタニンによる抗炎症作用のメカニズムの解明
  • 2023 - 2027 虚血性筋痛における脊髄神経節マクロファージを介した末梢感作機構の解明
  • 2021 - 2025 機能性胃腸症における胃の痛覚過敏への、CRF2を介した炎症性サイトカインの関与
  • 2023 - 2024 食用ビート成分による潰瘍性大腸炎の緩和作用の解明を介した新規治療法の開発
  • 2021 - 2024 末梢神経系グリア細胞を標的とした痛みの慢性化メカニズムの解明
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Papers (54)：
  • Tatsuya Ishikawa, Daisuke Uta, Hiroaki Okuda, Ilia Potapenko, Kiyomi Hori, Toshiaki Kume, Noriyuki Ozaki. Combined Experiments with <i>in Vivo</i> Fiber Photometry and Behavior Tests Can Facilitate the Measurement of Neuronal Activity in the Primary Somatosensory Cortex and Hyperalgesia in an Inflammatory Pain Mice Model. Biological and Pharmaceutical Bulletin. 2024. 47. 3. 591-599
  • Tatsuya Ishikawa, Koshi Murata, Hiroaki Okuda, Ilia Potapenko, Kiyomi Hori, Takafumi Furuyama, Ryo Yamamoto, Munenori Ono, Nobuo Kato, Yugo Fukazawa, et al. Pain-related neuronal ensembles in the primary somatosensory cortex contribute to hyperalgesia and anxiety. iScience. 2023. 26. 4. 106332-106332
  • Tatsuhide Tanaka, Hiroaki Okuda, Ayami Isonishi, Yuki Terada, Masahiro Kitabatake, Takeaki Shinjo, Kazuya Nishimura, Shoko Takemura, Hidemasa Furue, Toshihiro Ito, et al. Dermal macrophages set pain sensitivity by modulating the amount of tissue NGF through an SNX25-Nrf2 pathway. Nature immunology. 2023. 24. 3. 439-451
  • Hiroaki Okuda, Tatsuya Ishikawa, Kiyomi Hori, Nichakarn Kwankaew, Noriyuki Ozaki. Hedgehog signaling plays a crucial role in hyperalgesia associated with neuropathic pain in mice. Journal of neurochemistry. 2022. 162. 2. 220
  • Kouko Tatsumi, Kaoru Kinugawa, Ayami Isonishi, Masahiro Kitabatake, Hiroaki Okuda, Shoko Takemura, Tatsuhide Tanaka, Eiichiro Mori, Akio Wanaka. Olig2-astrocytes express neutral amino acid transporter SLC7A10 (Asc-1) in the adult brain. Molecular brain. 2021. 14. 1. 163-163
ｍore...
MISC (111)：
  • 田中達英, 奥田洋明, 和中明生. Dermal macrophages set pain sensitivity. 月刊臨床免疫・アレルギー科. 2024. 81. 1. 58-63
  • 奥田洋明, 石川達也, 堀紀代美, 尾崎紀之. 末梢神経系におけるHedgehogシグナルの活性化は痛覚過敏の発症に関与する. 日本解剖学会総会・全国学術集会抄録集(CD-ROM). 2023. 128th
  • 堀紀代美, 奥田洋明, 石川達也, 白石昌武, 中村恒夫, 尾崎紀之. 血管内皮増殖因子のスプライスバリアントVEGF-A165aとVEGF-A165bの量的バランスは下肢虚血に起因する筋の痛覚過敏に関与する. 日本解剖学会総会・全国学術集会抄録集(CD-ROM). 2023. 128th
  • KWANKAEW Nichakarn, KWANKAEW Nichakarn, 奥田洋明, 堀紀代美, 石川達也, 中村恒夫, 白石昌武, 尾崎紀之. Protective Effects of betanin on dextran sodium sulfate-induced colitis in mice. 日本解剖学会総会・全国学術集会講演プログラム・抄録集. 2022. 127th
  • OKUDA Hiroaki, KOZAKAI Yu, MON Aye-Mon, HORI Kiyomi, NICHAKARN Kwankaew, ISHIKAWA Tatsuya, OZAKI Noriyuki. Mechanisms of abnormal gastrointestinal motility and hyperalgesia in functional gastrointestinal disorders. Journal of Physiological Sciences (Web). 2021. 71. Supplement 1
ｍore...
Patents (3)：
Education (3)：
  • 2003 - 2007 Osaka University Graduate School of Medicine
  • 2001 - 2003 Setsunan University Graduate School of Pharmaceutical Sciences
  • 1997 - 2001 Setsunan University Faculty of Pharmaceutical Sciences Department of Pharmaceutical Sciences
Professional career (1)：
  • 博士(医学) (大阪大学)
Work history (3)：
  • 2024/04 - 現在 Osaka Medical and Pharmaceutical University
  • 2016/04 - 2024/03 Kanazawa University Institute of Medical, Pharmaceutical and Health Sciences, Faculty of Medicine
  • 2007/04 - 2016/03 Nara Medical University
Awards (1)：
  • 2017/03 - 日本解剖学会 奨励賞
Association Membership(s) (4)：
JAPANESE ASSOCIATION FOR THE STUDY OF PAIN ,  JAPANESE SOCIETY OF NEUROLOGY ,  THE JAPANESE SOCIETY FOR NEUROCHEMISTRY ,  THE JAPANESE ASSOCIATION OF ANATOMISTS
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