Rchr
J-GLOBAL ID：201801020312622547   Update date: Jan. 30, 2024

Oka Chio

オカ チオ | Oka Chio
Affiliation and department：
Nara Institute of Science and Technology Biological Science

About Nara Institute of Science and Technology Biological Science


Job title： Assistant Professor
Research field  (1)： Pathobiochemistry
Research theme for competitive and other funds  (8)：
  • 2022 - 2025 加齢黄斑変性の発症に関わるセリンプロテアーゼHtrA1の基質の同定と機能解析
  • 2021 - 2024 破骨細胞におけるDAP12を介したITAMシグナル経路を制御する分子機構の解明
  • 2019 - 2023 加齢黄斑変性の発症に関わるセリンプロテアーゼHtrA1の基質の同定と機能解析
  • 2005 - 2007 Study on HtrA Serine Protea we Family Proteins Which Inhibit Signaling of TGF-βs
  • 2005 - 2006 How HtrA1 serine protease inhibit TGF-β signal and is involved in arthritis ?
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Papers (38)：
  • Naruemon Wikan, Jiraporn Tocharus, Chio Oka, Sivanan Sivasinprasasn, Waraluck Chaichompoo, Apichart Suksamrarn, Chainarong Tocharus. The capsaicinoid nonivamide suppresses the inflammatory response and attenuates the progression of steatosis in a NAFLD-rat model. Journal of biochemical and molecular toxicology. 2023. 37. 3. e23279
  • Jirakhamon Sengking, Chio Oka, Nuttapong Yawoot, Jiraporn Tocharus, Waraluck Chaichompoo, Apichart Suksamrarn, Chainarong Tocharus. Protective Effect of Neferine in Permanent Cerebral Ischemic Rats via Anti-Oxidative and Anti-Apoptotic Mechanisms. Neurotoxicity research. 2022. 40. 5. 1348-1359
  • Toshiyuki Ko, Seitaro Nomura, Shintaro Yamada, Kanna Fujita, Takanori Fujita, Masahiro Satoh, Chio Oka, Manami Katoh, Masamichi Ito, Mikako Katagiri, et al. Cardiac fibroblasts regulate the development of heart failure via Htra3-TGF-β-IGFBP7 axis. Nature communications. 2022. 13. 1. 3275-3275
  • Chio Oka, Razwa Saleh, Yasumasa Bessho, Hasan Mahmud Reza. Interplay between HTRA1 and classical signalling pathways in organogenesis and diseases. Saudi Journal of Biological Sciences. 2022. 29. 4. 1919-1927
  • Miki Nishio, Takuya Matsuura, Shunya Hibi, Shiomi Ohta, Chio Oka, Noriaki Sasai, Yasumasa Ishida, Eishou Matsuda. Heterozygous loss of Zbtb38 leads to early embryonic lethality via the suppression of Nanog and Sox2 expression. Cell proliferation. 2022. e13215
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MISC (8)：
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