Rchr
J-GLOBAL ID:201801020524042958   Update date: Jun. 16, 2026

Fukuda Masahiro

Fukuda Masahiro
Affiliation and department:
Job title: Assistant Professor / Research Associate / Instructor
Homepage URL  (1): http://park.itc.u-tokyo.ac.jp/hekato_lab/
Research field  (1): Structural biochemistry
Research keywords  (4): Cryo electron microscopy ,  X-ray crystallography ,  Membrane proteins ,  Structural biology
Research theme for competitive and other funds  (10):
  • 2024 - 2029 生成的デザインのための量子ビームタンパク質分子動画解析
  • 2025 - 2028 立体構造解析と機能解析から挑む「タンパク質ファミリー」という概念への挑戦
  • 2024 - 2027 『光膜輸送学』-光による膜輸送の自在制御への挑戦
  • 2023 - 2025 新規カリウムチャネルロドプシンによるカリウム選択性の構造基盤の解明
  • 2022 - 2025 -
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Papers (22):
  • Asato Kojima, Kouki Kawakami, Naoya Kobayashi, Kazuhiro Kobayashi, Toshiki E. Matsui, Kohei Uemoto, Yuzhong Gu, Masahiro Fukuda, Hideaki E. Kato. A Rapid and Universal Pipeline for High-Resolution GPCR Structure Determination through In Silico Construct Optimization and de novo Protein Design. bioRxiv. 2026
  • Kazuhiro Kobayashi, Kouki Kawakami, Toshiki E. Matsui, Shun Yokoi, Masahiro Fukuda, Tomohiro J. Narita, Hiroki Arai, Mai Tambo, Takashi Sumikama, Manae Tatsumi, et al. The dynamic basis of G-protein recognition and activation by a GPCR. Nature. 2026. 652. 8110. 812-821
  • Yuka Takeno, Seiya Tajima, Suhyang Kim, Masaki Tsujimura, Yuma Ito, Masahiro Sugiura, Yo Yamashita, Koichiro E. Kishi, Masahiro Fukuda, Seiwa Nakamura, et al. Structural basis for color tuning and passive ion conductance in red-shifted pump-fold channelrhodopsin ChR024. 2025
  • Shunki Takaramoto, Chenxiang Zhao, Masayuki Karasuyama, Frederik Schulz, Masaya Watanabe, Yuma Kawasaki, Takashi Nagata, Masae Konno, Naoya Morimoto, Masahiro Fukuda, et al. Functional characterization of red-shifted rhodopsin channels from giant viruses explored by a machine-learning model for long-wavelength optogenetics. 2025
  • Keisei Shibata, Yuma Kawasaki, Shunki Takaramoto, Masaya Watanabe, Masahiro Fukuda, Ryohei Ono, Hideaki E Kato, Hidefumi Akiyama, Keiichi Inoue. Structural Changes in the Retinal Chromophore and Ion-Conducting Pathway of an Anion Channelrhodopsin GtACR1. The journal of physical chemistry letters. 2025. 6234-6241
more...
MISC (13):
  • Mai Kugawa, Kouki Kawakami, Ryoji Kise, Carl- Mikael Suomivuori, Masaki Tsujimura, Kazuhiro Kobayashi, Asato Kojima, Wakana J. Inoue, Masahiro Fukuda, Toshiki E. Matsui, et al. Structural insights into allosteric activation and inactivation mechanisms of FFA2. PROTEIN SCIENCE. 2025. 34
  • 福永彩美, 福永彩美, 川上耕季, 度会晃行, 小柳淳暉, 福田昌弘, 小林和弘, 松井俊貴, GENG Lang, SCOTT Daniel, et al. 社会性行動を制御するバソプレシン・オキシトシン交差認識の理解. 日本生化学会大会(Web). 2025. 98th
  • 福永彩美, 川上耕季, 小柳淳暉, 福田昌弘, 辻村真樹, 小林和弘, 松井俊貴, SCOTT Daniel J., 加藤英明, 加藤英明. Molecular mechanism of neuropeptide cross-recognition by the vasopressin receptor. 日本薬学会年会要旨集(Web). 2024. 144th
  • 九川真衣, 木瀬亮次, 福田昌弘, 福田昌弘, 川上耕季, 川上耕季, 川上耕季, 松井俊貴, 小林和弘, 小林和弘, et al. Ligand recognition and activation mechanisms of Free Fatty Acid Receptor 2. 日本薬学会年会要旨集(Web). 2024. 144th
  • 川上耕季, 小林和弘, 松井俊貴, 福田昌弘, 新井大輝, 辰己茉菜絵, 小柳淳暉, 草木迫司, JANETZKO John, 山下恵太郎, et al. ニューロテンシン受容体によるGタンパク質活性化過程の可視化. GPCR研究会プログラム・抄録集. 2024. 18th
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Lectures and oral presentations  (12):
  • 構造から理解する 光・化学受容体の分子機能
    (第4回 タンパク質シンポジウム 2026)
  • イオン輸送型ロドプシンの構造的理解 〜チャネルとして機能するために〜
    (第98回 日本生化学会 年会 シンポジウム3S13a 「サイズ横断構造生物学 〜タンパク質の立体構造からの更なる展開〜」 2025)
  • Structural diversity of light-gated ion channels (channelrhodopsins)
    (2025)
  • Structural basis for ion selectivity in potassium-selective channelrhodopsins
    ("Molecular Movies" International Symposium 2023 2023)
  • 構造から見るイオン輸送型ロドプシンの分子機構
    (大阪大学蛋白質研究所セミナー 生命のしなやかさに着目したタンパク質研究の現状と展望 2023)
more...
Works (1):
  • マクロな結晶からなるミクロな結晶構造(ニコン賞受賞)
    福田 昌弘 2013 -
Education (4):
  • 2015 - 2018 The University of Tokyo Graduate school of Science Department of Biological Sciences
  • 2012 - 2014 The University of Tokyo Graduate school of Science Department of Biophysics and Biochemistry
  • 2008 - 2012 The University of Tokyo Faculty of science Department of Biophysics and Biochemistry
  • 2005 - 2008 岡山県立岡山操山高等学校
Professional career (1):
  • 博士(理学) (東京大学)
Work history (6):
  • 2024/04 - 現在 The University of Tokyo Research Center for Advanced Science and Technology Assistant professor
  • 2019/05 - 2024/03 The University of Tokyo Komaba institute for Science, Graduate School of Arts and Sciences Project assistant professor
  • 2018/04 - 2019/03 Keio University Faculty of Pharmacy Research associate
  • 2016/04 - 2018/03 The University of Tokyo Graduate School of Science
  • 2014/07 - 2015/03 The University of Tokyo Faculty of Science Project researcher
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Awards (2):
  • Cold Spring Harbor Asia (CSHA) 2015 Fellowship Award
  • The University of Tokyo Research award of graduate school of science in 2014
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