Research theme for competitive and other funds (5)：
2022 - 2025 生体内の腫瘍細胞死が及ぼす腫瘍微小環境の変化
2019 - 2022 The role of humoral immunity in tumor microenvironment
2016 - 2018 IL-4をターゲットとした癌免疫療法の開発
2014 - 2017 Development of a novel anti-cancer immune therapy using the synthetic oligonucleotide containing poly-G motif
2013 - 2015 腫瘍環境における慢性炎症・免疫細胞の機能解析と癌治療への応用
Papers (91)：
Sakura Hiraide Taniguchi, Keigo Komine, Noriko Takenaga, Yuya Yoshida, Keiju Sasaki, Yoshifumi Kawamura, Yuki Kasahara, Kota Ouchi, Hiroo Imai, Ken Saijo, et al. FOLFIRI Chemotherapy for Patients With Metastatic Urachal Carcinoma. Anticancer research. 2023. 43. 12. 5699-5704
Hiroo Imai, Ken Saijo, Yoshifumi Kawamura, Shuto Kodera, Keigo Komine, Tomoyuki Iwasaki, Noriko Takenaga, Yuki Kasahara, Kota Ouchi, Hidekazu Shirota, et al. Comparison of efficacy and safety between carboplatin-etoposide and cisplatin-etoposide combination therapy in patients with advanced neuroendocrine carcinoma, retrospective study. Oncology. 2023
Reio Ueta, Hiroo Imai, Ken Saijo, Yoshifumi Kawamura, Shuto Kodera, Keigo Komine, Kota Ouchi, Yuki Kasahara, Sakura Taniguchi, Yuya Yoshida, et al. Antibiotics May Interfere with Nivolumab Efficacy in Patients with Head and Neck Squamous Cell Carcinoma. Oncology. 2023. 1-8
Sho Umegaki, Hidekazu Shirota, Yuki Kasahara, Tomoyuki Iwasaki, Chikashi Ishioka. Distinct role of CD8 cells and CD4 cells in antitumor immunity triggered by cell apoptosis using a Herpes simplex virus thymidine kinase/ganciclovir system. Cancer science. 2023. 114. 8. 3076-3086
Shonosuke Wakayama, Kota Ouchi, Shin Takahashi, Yasuhide Yamada, Yoshito Komatsu, Ken Shimada, Tatsuro Yamaguchi, Hidekazu Shirota, Masanobu Takahashi, Chikashi Ishioka. TP53 Gain-of-Function Mutation is a Poor Prognostic Factor in High-Methylated Metastatic Colorectal Cancer. Clinical colorectal cancer. 2023
Keigo Komine, Masanobu Takahashi, Sakura Hiraide, Hideharu Yamada, Mari Tsubata, Masahiro Takahashi, Shin Takahashi, Hidekazu Shirota, Tetsuya Niihori, Yoko Aoki, et al. Adoption of multigene panel testing for hereditary cancer "CancerNext" in Tohoku University Hospital. ANNALS OF ONCOLOGY. 2019. 30
Chikashi Ishioka, Muneaki Shimada, Hidekazu Shirota, Hideki Tokunaga, Keigo Komine, Toru Furukawa, Nobuo Yaegashi. System maintenance of the core hospital for cancer genome medical care: action in the Tohoku University Hospital. CANCER SCIENCE. 2018. 109. 612-612
Keigo Komine, Masanobu Takahashi, Sakura Hiraide, Sho Umegaki, Yoshifumi Kawamura, Hideharu Yamada, Akira Okita, Sonoko Chikamatsu, Yuki Kasahara, Yoshinari Okada, et al. Three cases of venous thromboembolism in advanced cancer patients. ANNALS OF ONCOLOGY. 2018. 29. 8-8
1990 - 1996 Fukushima Medical University School of Medicine
Professional career (1)：
Ph. D. (Tohoku University)
Work history (5)：
2017/08 - 現在 東北大学医学系研究科 地域がん医療推進センター 准教授
2012/06 - 2017/07 東北大学医学系研究科 地域がん医療推進センター 講師
2008/04 - 2012/05 米国国立衛生研究所 国立癌研究所 スタッフサイエンティスト
2007/04 - 2008/03 東北大学医学系研究科 感染症・呼吸器内科 助教
2002/04 - 2007/03 米国食品医薬品庁 生物製剤評価研究センター 博士研究員
Awards (1)：
2011 - National Cancer Institute, NIH Technology Transfer Award
Association Membership(s) (6)：
JAPANESE SOCIETY OF ALLERGOLOGY
, THE JAPANESE CANCER ASSOCIATION
, JAPAN SOCIETY OF CLINICAL ONCOLOGY
, THE JAPANESE SOCIETY FOR IMMUNOLOGY
, JSMO
, THE JAPANESE SOCIETY OF INTERNAL MEDICINE
