Hasebe Fumihito

ハセベフミヒト | Hasebe Fumihito

Affiliation and department：
Homepage URL (1)： https://applied-microbiology-fpu.com/

Research field (1)： Applied microbiology

Research theme for competitive and other funds (6)：

2022 - 2027 Development of novel peptide compounds derived from microorganisms using new technology.
2022 - 2025 細菌における新規メチオニン生合成経路の解明
2023 - 2024 放線菌における新規メチオニン生合成経路の探索
2020 - 2022 Studies on novel feedback mechanism of methionine biosynthetic enzyme
2017 - 2020 Mechanistic analysis of high-yield protein production in E. coli for the production of natural products

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Papers (20)：

Fumihito Hasebe, Kazuya Adachi, Chitose Maruyama, Yoshimitsu Hamano. Discovery of a novel methionine biosynthetic route via O-phospho-l-homoserine. Applied and environmental microbiology. 2024. e0124724
Kohei Kaneda, Yamato Takeuchi, Kazuya Yamanaka, Fumihito Hasebe, Chitose Maruyama, Yoshimitsu Hamano. Cell-penetrating activity of a short-chain ε-poly-l-α-lysine. Journal of bioscience and bioengineering. 2024
Fumihito Hasebe, Kazuya Adachi, Kazuya Yamanaka, Tadao Oikawa, Chitose Maruyama, Yoshimitsu Hamano. Constitutive and high gene expression in the diaminopimelate pathway accelerates ε-poly-L-lysine production in Streptomyces albulus. The Journal of antibiotics. 2023. 76. 9. 522-531
Sumire Kurosawa, Hironori Okamura, Ayako Yoshida, Takeo Tomita, Yusuke Sone, Fumihito Hasebe, Tetsuro Shinada, Hirosato Takikawa, Saori Kosono, Makoto Nishiyama. Mechanisms of Sugar Aminotransferase-like Enzymes to Synthesize Stereoisomers of Non-proteinogenic Amino Acids in Natural Product Biosynthesis. ACS Chemical Biology. 2023
Tomoharu Motoyama, Yuta Yamamoto, Chiharu Ishida, Fumihito Hasebe, Yui Kawamura, Yasuteru Shigeta, Sohei Ito, Shogo Nakano. Reaction Mechanism of Ancestral l-Lys α-Oxidase from Caulobacter Species Studied by Biochemical, Structural, and Computational Analysis. ACS Omega. 2022. 7. 48. 44407-44419

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MISC (3)：

杉浦紗也加, 中野祥吾, 中野祥吾, 丹羽正純, 長谷部文人, 松井大亮, 伊藤創平. Identification of a novel L-Lysine-alpha-oxidase and elucidation of its reaction mechanism. 日本生物工学会大会講演要旨集. 2021. 73rd
中野祥吾, 中野祥吾, 小塚康平, 南野優季, 烏田裕香, 長谷部文人, 伊藤創平. 新規祖先型L-アミノ酸酸化酵素の構造機能解析とD-アミノ酸光学分割への応用. ビタミン. 2021. 95. 4
Kenichi Matsuda, Fumihito Hasebe, Takeo Tomita, Yu Shiwa, Hirofumi Yoshikawa, Kazuo Shin-ya, Tomohisa Kuzuyama, Makoto Nishiyama. Screening of secondary metabolites biosynthesized with novel amino acid carrier protein system. FASEB JOURNAL. 2014. 28. 1

Professional career (1)：

Work history (3)：

2021/04 - 現在 Fukui Prefectural University Faculty of Biotechnology Department of Bioscience
2016/04 - 2021/03 University of Shizuoka School of Food and Nutritional Sciences
2014/04 - 2016/03 The University of Tokyo Biotechnology Research Center

Awards (4)：

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