Shimoji Miyuki

Research theme for competitive and other funds (2)：

2021 - 2024 Adoptive CTL therapy using neo-antigen-specific TCR-gene induced T cells
2019 - 2022 Development of new immuno-cell therapy for the treatment of refractory malignant ascites and pleural effusion

Papers (39)：

Miyuki Shimoji, Hiroya Akabori. Application of novel 3D culture device for human omental adipocytes and macrophages derived from surgery. bioRxiv. 2024
下地みゆき, 村田聡, Sihombing Andreas M., 竹林克士, 児玉泰一, 北村直美, 小島正継, 森治樹, 北村美奈, 徳田彩, et al. ヒト膵臓がん細胞株を用いた温熱療法のアポトーシスにおける膜結合性グルタチオントランスフェラーゼ1の影響(Effect of microsomal glutathione transferase1 on apoptosis in human pancreatic cancer cell lines under hyperthermia). 日本癌学会総会記事. 2023. 82回. 238-238
村田聡, Sihombing Andreas, 下地みゆき, 竹林克士, 貝田佐知子, 児玉泰一, 北村直美, 小島正継, 森治樹, 北村美奈, et al. 手術で誘導される腹腔内炎症による腹膜転移の促進(Peritoneal metastasis promoted by surgery-induced peritoneal inflammation). 日本癌学会総会記事. 2023. 82回. 260-260
Michiaki Kojima, Kanami Machida, Sumie Cho, Daichi Watanabe, Hiroyuki Seki, Miyuki Shimoji, Ayuko Imaoka, Hiroshi Yamazaki, F. Peter Guengerich, Katsunori Nakamura, et al. The influence of temperature on the metabolic activity of CYP2C9, CYP2C19, and CYP3A4 genetic variants in vitro. Xenobiotica. 2023. 53. 5. 357-365
Andreas Michael Sihombing, Satoshi Murata, Miyuki Shimoji, Toru Miyake, Katsushi Takebayashi, Hirokazu Kodama, Aya Tokuda, Masatsugu Kojima, Tomoyuki Ueki, Naomi Kitamura, et al. CD44-positive Cancer Stem-like Cells as a Potential Source of Peritoneal Metastasis After Surgery. Anticancer Research. 2023. 43. 6. 2491-2500

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MISC (20)：

村田聡, Sihombing Andreas M., 山口剛, 貝田佐知子, 竹林克士, 児玉泰一, 三宅亨, 下地みゆき, 飯田洋也, 谷眞至. 胃癌術後腹膜再発におけるCD44陽性癌幹細胞様細胞と外科的炎症について. 日本外科学会定期学術集会抄録集. 2022. 122回. DP-6
村田聡, Sihombing Andreas M., 下地みゆき, 竹林克士, 児玉泰一, 貝田佐知子, 山口剛, 三宅亨, 小島正継, 植木智之, et al. CD44陽性癌幹細胞をターゲットとした胃癌術後腹膜再発予防法の開発. 日本癌治療学会学術集会抄録集. 2021. 59回. O47-6
シホンビング・アンドレアス・マイケル, 村田聡, 下地みゆき, 中尾さくら, 竹林克士, 児玉泰一, 小島正継, 植木智之, 北村直美, 北村美奈, et al. CD44陽性がん幹細胞様細胞と胃がん腹膜転移との関係. 日本癌学会総会記事. 2021. 80回. [E11-4]
村田聡, 下地みゆき, 小島正継, 北村美奈, シホンビング・アンドレアス・マイケル, 中尾さくら, 北村直美, 植木智之, 竹林克士, 児玉泰一, et al. 癌抗原特異的免疫寛容マウスの癌性腹水中の腫瘍関連リンパ球(TAL)を用いた癌抗原特異的CTLの誘導. 日本癌学会総会記事. 2021. 80回. [P12-4]
シホンビング・アンドレアス・マイケル, 村田聡, 下地みゆき, 中尾さくら, 竹林克士, 児玉泰一, 小島正継, 植木智之, 北村直美, 北村美奈, et al. CD44陽性がん幹細胞様細胞と胃がん腹膜転移との関係. 日本癌学会総会記事. 2021. 80回. [E11-4]

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Books (2)：

Encyclopedia of Movement Disorders: Variant Creutzfeldt-Jakob Disease
Elsevier, London, UK 2010
Toxicology of glutathione transferases
Taylor & Francis 2006 ISBN:0849329833

Lectures and oral presentations (4)：

Effects of hyperthermia at 42oC on apoptosis and ferroptosis in human pancreatic cancer cells
(The 83rd Annual Meeting of the Japanese Cancer Assopciation 2024)
Effects of Hyperthermia on CD44 Expression, Apoptosis, Autophagy and Ferroptosis in Human Pancreatic Cancer Cells
(The 41st Annual Meeting of Japanese Society for Thermal Medicine 2024)
Effects of Hyperthermia on CD44 Expression, Apoptosis and Autophagy in Human Pancreatic Cancer Cells
(The 7th JCA-AACR Special Joint Conference, The Latest Advances in Pancreatic Cancer Research: from Basic Science to Therapeutics 2022)
Characterization of Tumor-associated lymphocytes in peritoneal metastasis of immune-tolerant mice
(The 1 st JCA-AACR Precision Cancer Medicine International Conference 2021)

Work history (10)：

2018/05 - 現在 Shiga University of Medical Science Surgery
2016/11 - 2018/03 Graduate School of Medicine, University of the Ryukyus
2009/01 - 2009/12 Case Western Reserve University, Cleveland, OH Institute of Pathology
2008/10 - 2009/12 Case Western Reserve University, Cleveland, OH Ophthalmology
2008/05 - 2008/09 University of Texas Medical Branch, Galveston, TX Pharmacology and Toxicology

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