Rchr
J-GLOBAL ID：201801021189696073   Update date: Nov. 16, 2024

Kuniishi Hiroshi

Kuniishi Hiroshi
Affiliation and department：
Research Center for Child Mental Development, University of Fukui, Division of Development of Mental Functions

About Research Center for Child Mental Development, University of Fukui, Division of Development of Mental Functions


Job title： Assistant professor
Research field  (3)： Psychiatry ,  Nervous system function ,  Neuroscience - general
Research keywords  (12)： 神経回路 ,  シナプス ,  情動 ,  社会性 ,  前頭前野 ,  行動薬理学 ,  光遺伝学 ,  前帯状回 ,  扁桃体 ,  眼窩前頭皮質 ,  幼少期ストレス ,  ストレス
Research theme for competitive and other funds  (9)：
  • 2023 - 2027 Glutathione system in the brain of children with autism spectrum disorder
  • 2024 - 2026 耳介迷走神経刺激による脳内炎症抑制機構の解明
  • 2023 - 2026 The mechanism of action of transcutaneous vagus nerve stimulation to treat psychiatric disorders.
  • 2022 - 2025 幼少期ストレスモデルマウスに対する前頭葉ニューロモジュレーションの改善効果検討
  • 2021 - 2024 社会性を制御する前頭葉-扁桃体シナプスの発達の臨界期とその神経基盤の解明
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Papers (15)：
  • Masakazu Agetsuma, Azumi Hatakeyama, Daisuke Yamada, Hiroshi Kuniishi, Eri Takeuchi, Shinji Tsuji, Chihiro Ito, Tomoko Kobayashi, Atsushi Noritake, Yoshitsugu Aoki, et al. Low-invasive, wide-field, and cellular resolution two-photon imaging of neural population activity in brainstem and nucleus tractus solitarii. bioRxiv. 2024
  • Yoshitaka Kawashima, Misa Yamada, Hiroki Furuie, Hiroshi Kuniishi, Kie Akagi, Tomoko Kawashima, Takamasa Noda, Mitsuhiko Yamada. Effects of riluzole on psychiatric disorders with anxiety or fear as primary symptoms: A systematic review. Neuropsychopharmacology reports. 2023
  • Hiroshi Kuniishi, Mitsuhiko Yamada. [Subregion-dependent synaptic changes in the orbitofrontal-amygdala pathways by adolescent social isolation in mice]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 2023. 158. 1. 47-50
  • 國石 洋, 竹内 絵理, 関口 正幸, 山田 光彦, 松崎 秀夫. マウス耳介神経刺激による文脈的恐怖消去学習と内側前頭前野シナプス伝達への効果. 日本脳科学会プログラム・抄録集. 2022. 49回. 28-28
  • Hiroshi Kuniishi, Yuko Nakatake, Masayuki Sekiguchi, Mitsuhiko Yamada. Adolescent social isolation induces distinct changes in the medial and lateral OFC-BLA synapse and social and emotional alterations in adult mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2022
ｍore...
MISC (10)：
  • 國石 洋, 山田 光彦. 思春期の社会経験剥奪による眼窩前頭皮質-扁桃体経路の小領域特異的なシナプス機能変化. 日本薬理学雑誌. 2023. 158. 1. 47-50
  • 橋本泰昌, 國石洋, 境和久, 福島雄大, DU Xuan, 本橋紀夫, 今村道博, 位高啓史, 一戸紀孝, 関口正幸, et al. 短いジストロフィンDp140は,興奮性シナプス伝達を抑制し,自閉症様行動を引き起こす. 日本筋学会学術集会プログラム・抄録集. 2021. 7th. 110-110
  • Hiroshi Kuniishi, Masayuki Sekiguchi, Mitsuhiko Yamada. The contribution of orbitofrontal cortex to stress-related psychiatric disorders: stress induced synaptic change in the orbitofrontal-basolateral amygdala pathway. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 2021. 156. 2. 62-65
  • 國石洋, 國石洋, 関口正幸, 山田光彦. 幼少期の社会隔離ストレスはマウスの情動行動と眼窩前頭皮質-扁桃体経路のシナプス伝達の異常を引き起こす. 国立精神・神経医療研究センター精神保健研究所研究報告会プログラム・抄録集(Web). 2021. 32nd
  • 橋本泰昌, 國石洋, 國石洋, 関口正幸, 青木吉嗣. エクソン53スキップ療法はDMDモデルマウスの社会性行動異常と扁桃体シナプス異常を改善させる. 神経治療学(Web). 2021. 38. 6
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Lectures and oral presentations  (32)：
  • Auricular vagus nerve stimulation rescues social deficit in social isolation or maternal immune activation mice and activates social brain regions.
    (NEURO2024 2024)
  • 思春期社会隔離マウスの社会性異常に対する耳介迷走神経刺激の効果
    (第45回日本生物学的精神医学会年会 2023)
  • Facilitative effect of the auricular vagus nerve stimulation on extinction learning of contextual fear in mice.
    (The 46th Annual Meeting of the Japan Neuroscience Society, Symposia, Homeostasis and pathological mechanism by neural network-associated organ interaction system 2023)
  • Critical period for effects of resocialization on social isolation-induced social and the OFC-amygdala synaptic deficits
    (The 66th Annual Meeting of the Japanese Society for Neurochemistry 2023)
  • Adolescent social isolation induces pathway-selective functional changes in the medial and lateral orbitofrontal-amygdala circuits.
    (17Th Meeting of the Asian-Pafific Society for Neurochemistry 2023)
ｍore...
Education (1)：
  • 2014 - 2017 Tottori University Graduate School of Medical Sciences Institute of Regenerative Medicine and Biofunction
Professional career (1)：
  • 博士(再生医科学) (鳥取大学)
Work history (4)：
  • 2022/06 - 現在 Research Center for Child Mental Development, University of Fukui Division of Development of Mental Functions Assistant professor
  • 2021/04 - 2022/05 National Center of Neurology and Psychiatry Dept. Neuropsychopharmacology Japan Society for the Promotion of Science, Research fellow (PD)
  • 2017/04 - 2022/03 National Center of Neurology and Psychiatry Department of Degenerative Neurological Diseases Adjunct Scientist
  • 2017/04 - 2021/03 National Center of Neurology and Psychiatry Dept. Neuropsychopharmacology Research fellow
Awards (8)：
  • 2023/07 - The Award for Young Investigator of Japanese Society for Neurochemistry
  • 2023/01 - Invited Young Investigator 17th Meeting of the Asian-Pacific Society for Neurochemistry (APSN2023)
  • 2022/12 - Japan Brain Science society Young Investigator Award
  • 2022/11 - 福井大学 2022年度(前期)医学系部門教員等による優秀論文賞
  • 2021/03 - National Institute of Mental Health, National Center of Neurology and Psychiatry Young Investigator Award
Show all
Association Membership(s) (5)：
THE JAPANESE SOCIETY OF NEUROPSYCHOPHARMACOLOGY ,  THE JAPAN NEUROSCIENCE SOCIETY ,  Japan Brain Science Society ,  Japanese Society for Neurochemistry ,  Japanese Pharmacological Society
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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