Research field (2)：
Digestive surgery
, Tumor diagnostics and therapeutics
Research keywords (2)：
Gastroenterological Surgery
, Gene therapy
Research theme for competitive and other funds (17)：
2024 - 2027 原発性脊椎腫瘍に対する腫瘍融解ウイルス療法の確立
2023 - 2026 脊椎脊髄腫瘍に対する腫瘍融解ウイルス療法の確立
2022 - 2025 Immune molecular mechanism for enhancing antitumor potency of a next-generation oncolytic virus by pre-immunization
2021 - 2024 Exploration of metabolic factors to inhibit tumor-specific p53 gene therapy in pancreatic cancer
2019 - 2022 Development of a next-generation viral agent targeting immunosuppression by crosstalk in the pancreatic cancer microenvironment
2017 - 2020 Imaging system for progression of gastrointestinal cancer and its application to anti-metastasis therapy
2016 - 2019 Preclinical study of tumor-specific p53 gene therapy against refractory pancreatic cancer
2016 - 2019 Development of the Dual fluorescent cytology with tumor-specific viruses for gastrointestinal cancer precision medicine
2015 - 2017 Analysis for intraperitoneal cancer microenvironment to elucidate the biological mechanism of peritoneal metastasis of gastrointestinal cancer
2014 - 2017 Development of anti-metastasis therapy in the inflammation-related gastric cancer progression
2014 - 2016 Novel targeting therapy to cancer-associated fibroblasts for treatment-resistant carcinomas
2013 - 2016 Development of novel microRNA-based therapy against KRAS/BRAF-mutant colorectal cancer
2013 - 2016 Photoimmunotherapy for gastrointestinal cancer
2011 - 2013 Fluorescence-guided detection and genetic analysis of circulating tumor cells
2011 - 2013 Tumor suppressor FHIT regulates tumor invasion of pancreatic cancer cells via inhibiting association of Ezrin and Actin cytoskeleton
2011 - 2012 Circulating Tumor Cell of Gastrointestinal Stromal Tumor
2010 - 2012 Induction of autophagic cell death via microRNA-mediated gene regulatory network
Show all
Papers (152)：
Koji Demiya, Hiroshi Tazawa, Hiroya Kondo, Miho Kure, Yusuke Mochizuki, Tadashi Komatsubara, Aki Yoshida, Koji Uotani, Joe Hasei, Tomohiro Fujiwara, et al. p53-armed oncolytic virotherapy induces abscopal effect in osteosarcoma by promoting immunogenic cell death. Molecular therapy. Oncology. 2024. 32. 3. 200845-200845
Teruki Kobayashi, Kazuhiro Noma, Seitaro Nishimura, Takuya Kato, Noriyuki Nishiwaki, Toshiaki Ohara, Tomoyoshi Kunitomo, Kento Kawasaki, Masaaki Akai, Satoshi Komoto, et al. Near-infrared Photoimmunotherapy Targeting Cancer-Associated Fibroblasts in Patient-Derived Xenografts Using a Humanized Anti-Fibroblast Activation Protein Antibody. Molecular cancer therapeutics. 2024. 23. 7. 1031-1042
Motoyasu Tabuchi, Satoru Kikuchi, Hiroshi Tazawa, Tomohiro Okura, Toshihiro Ogawa, Ema Mitsui, Yuta Une, Shinji Kuroda, Hiroki Sato, Kazuhiro Noma, et al. Functional remodeling of intraperitoneal macrophages by oncolytic adenovirus restores anti-tumor immunity for peritoneal metastasis of gastric cancer. Molecular therapy. Oncology. 2024. 32. 2. 200806-200806
坂本 真樹, 黒田 新士, 垣内 慶彦, 橋本 将志, 八木 千晶, 杉本 龍馬, 濱田 侑紀, 吉田 有佑, 門脇 大輔, 半澤 俊哉, et al. Commensal bacteria and tumor immunity Butyrate enhances the antitumor efficacy of telomerase-specific oncolytic adenoviruses. 日本癌学会総会記事. 2023. 82回. 1660-1660
加藤 卓也, 野間 和広, 古澤 あき, 福島 啓司, 高尾 誠一郎, 田澤 大, チョイキー・ピーター, 小林 久隆, 藤原 俊義. Selective depletion of PMN-MDSCs in tumor be ds with near infrared photoimmunotherapy enhances host immune response. 日本癌学会総会記事. 2023. 82回. 1758-1758
宇根 悠太, 菊地 覚次, 田澤 大, 黒田 新士, 大原 利章, 野間 和広, 香川 俊輔, 藤原 俊義. Development of the 3D model of peritoneum structure to explore the biology of gastric cancer peritoneal metastasis. 日本癌学会総会記事. 2023. 82回. 1858-1858
1998/04 - 2000/03 Hokkaido University School of Medicine
1997/04 - 1998/03 Akita University University Hospital
1995/04 - 1997/03 秋田県厚生連雄勝中央病院 外科 研修医
Show all
Committee career (3)：
2022/06 - 現在 日本バイオセラピィ学会 評議員
2019/01 - 現在 日本癌学会 評議員
2017/07 - 現在 日本遺伝子細胞治療学会 評議員
Awards (4)：
2013/06 - 岡山医学会 がん研究奨励賞
2012/06 - 日本遺伝子治療学会 アンジェスMG賞
2010/05 - 財団法人 富山県ひとづくり財団 とやま賞(医薬部門)
2007/09 - 日本疾患モデル学会 優秀発表賞
Association Membership(s) (9)：
日本がん予防学会
, 米国癌学会
, 日本バイオセラピィ学会
, 日本消化器癌発生学会
, JAPAN SOCIETY OF CLINICAL ONCOLOGY
, 日本遺伝子細胞治療学会
, THE JAPANESE CANCER ASSOCIATION
, THE JAPANESE SOCIETY OF GASTROENTEROLOGICAL SURGERY
, JAPAN SURGICAL SOCIETY
