Art

J-GLOBAL ID：201802212186173396   Reference number：18A1114775

IRFinder: assessing the impact of intron retention on mammalian gene expression

IrFinder:哺乳類遺伝子発現に及ぼすイントロン保持の影響の評価【JST・京大機械翻訳】

Author (22)： Middleton Robert (Bioinformatics Laboratory, Centenary Institute, Camperdown, Australia) ,  Gao Dadi (Bioinformatics Laboratory, Centenary Institute, Camperdown, Australia) ,  Gao Dadi (Molecular Neurogenetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, Boston, USA) ,  Gao Dadi (Boston & Harvard Medical School, Boston, USA) ,  Gao Dadi (Gene & Stem Cell Therapy Program, Centenary Institute, Camperdown, Australia) ,  Thomas Aubin (CNRS, UPR 1142, Montpellier, France) ,  Singh Babita (Pompeu Fabra University, UPF, Barcelona, Spain) ,  Au Amy (Gene & Stem Cell Therapy Program, Centenary Institute, Camperdown, Australia) ,  Au Amy (Sydney Medical School, University of Sydney, Sydney, Australia) ,  Wong Justin J-L (Gene & Stem Cell Therapy Program, Centenary Institute, Camperdown, Australia) ,  Wong Justin J-L (Sydney Medical School, University of Sydney, Sydney, Australia) ,  Wong Justin J-L (Gene Regulation in Cancer Laboratory, Centenary Institute, University of Sydney, Camperdown, Australia) ,  Bomane Alexandra (Universite Paris Diderot, Sorbonne Paris Cite, Epigenetics and Cell Fate, UMR7216, CNRS, Paris, France) ,  Cosson Bertrand (Universite Paris Diderot, Sorbonne Paris Cite, Epigenetics and Cell Fate, UMR7216, CNRS, Paris, France) ,  Eyras Eduardo (Pompeu Fabra University, UPF, Barcelona, Spain) ,  Eyras Eduardo (Catalan Institution for Research and Advanced Studies, ICREA, Barcelona, Spain) ,  Rasko John E. J. (Gene & Stem Cell Therapy Program, Centenary Institute, Camperdown, Australia) ,  Rasko John E. J. (Sydney Medical School, University of Sydney, Sydney, Australia) ,  Rasko John E. J. (Cell and Molecular Therapies, Royal Prince Alfred Hospital, Camperdown, Australia) ,  Ritchie William (Bioinformatics Laboratory, Centenary Institute, Camperdown, Australia) ,  Ritchie William (CNRS, UPR 1142, Montpellier, France) ,  Ritchie William (CNRS, UMR 5203, Montpellier, France)
Material： Genome Biology (Web)
Volume： 18  Issue： 1  Page： 51  Publication year： 2017 
JST Material Number： U7384A  ISSN： 1474-760X  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Intron retention (IR) occurs w...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=18A1114775&from=J-GLOBAL&jstjournalNo=U7384A") }}

Thesaurus term： *intron ,  Cell Differentiation ,  database ,  *gene ,  *Mammalia ,  mRNA ,  *gene expression ,  RNA binding protein ,  cluster ,  Cell Cycle ,  Gene Expression Regulation ,  protein level ,  differentiation (biology) ,  developmental physiology ,  *Vertebrata ,  *molecular genetic phenomenon ,  Heredity
Semi thesaurus term： genetic regulation ,  蛋白質量 ,  影響評価 , 【Automatic Indexing@JST】

Author keywords (3)： mRNA splicing ,  Intron retention ,  Gene regulation

JST classification (1)： Gene expression  (EC02040Q)

Reference (37)：

• Nat Genet; Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing; Q Pan, O Shai, LJ Lee, BJ Frey, BJ Blencowe; 40; 2008; 1413-5; 10.1038/ng.259; CR1;
• Neuron; Cytoplasmic intron sequence-retaining transcripts can be dendritically targeted via ID element retrotransposons; PT Buckley, MT Lee, J-Y Sul, KY Miyashiro, TJ Bell, SA Fisher, J Kim, J Eberwine; 69; 2011; 877-84; 10.1016/j.neuron.2011.02.028; CR2;
• Mol Cell Biol; Mammalian nonsense codons can be cis effectors of nuclear mRNA half-life; P Belgrader, J Cheng, X Zhou, LS Stephenson, LE Maquat; 14; 1994; 8219-28; 10.1128/MCB.14.12.8219; CR3;
• Proc Natl Acad Sci U S A; Sequence conservation, relative isoform frequencies, and nonsense-mediated decay in evolutionarily conserved alternative splicing; D Baek, P Green; 102; 2005; 12813-8; 10.1073/pnas.0506139102; CR4;
• Curr Opin Genet Dev; Nonsense-mediated mRNA decay (NMD) in animal embryogenesis: to die or not to die, that is the question; J Hwang, LE Maquat; 21; 2011; 422-30; 10.1016/j.gde.2011.03.008; CR5;

Terms in the title (4)： 哺乳類 ,  遺伝子発現 ,  イントロン ,  影響の評価