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J-GLOBAL ID：201802213167522829   Reference number：18A0481703

Ameliorative effects of selenium on arsenic-induced cytotoxicity in PC12 cells via modulating autophagy/apoptosis

オートファジー/アポトーシスの調節を介してPC12細胞におけるヒ素誘導性の細胞毒性に及ぼすセレンの改善効果【Powered by NICT】

Author (9)： Rahman Md. Mostafizur (Graduate School of Environmental Science, Hokkaido University, Japan) ,  Rahman Md. Mostafizur (Department of Environmental Sciences, Jahangirnagar University, Bangladesh) ,  Uson-Lopez Rachael A. (Graduate School of Environmental Science, Hokkaido University, Japan) ,  Sikder Md. Tajuddin (Faculty of Health Sciences, Hokkaido University, Japan) ,  Tan Gongxun (Graduate School of Environmental Science, Hokkaido University, Japan) ,  Hosokawa Toshiyuki (Institute for the Advancement of Higher Education, Hokkaido University, Japan) ,  Saito Takeshi (Faculty of Health Sciences, Hokkaido University, Japan) ,  Kurasaki Masaaki (Graduate School of Environmental Science, Hokkaido University, Japan) ,  Kurasaki Masaaki (Faculty of Environmental Earth Science, Hokkaido University, Japan)
Material： Chemosphere  (Chemosphere. Science for Environmental Technology)
Volume： 196  Page： 453-466  Publication year： 2018 
JST Material Number： E0843A  ISSN： 0045-6535  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Arsenic is well known toxicant...

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Thesaurus term： *cytotoxicity ,  NF-kappaB ,  *PC12 cell ,  Western blotting ,  *selenium ,  antagonism ,  oxidative stress ,  intracellular accumulation ,  potentiation ,  *Autophagy ,  *arsenic ,  *Apoptosis ,  Caspase 3 ,  Cell Survival ,  antioxidant activity ,  bioassay

Author keywords (6)： Malondialdehyde ,  Autophagy ,  Apoptosis ,  Cytotoxicity ,  Glutathione ,  mTOR/Akt-pathway

JST classification (2)： Influence on animals  (EE05040R) ,  Heavy metals and their compounds in general  (SB05021R)

Terms in the title (8)： オートファジー ,  アポトーシス ,  調節 ,  PC12細胞 ,  ヒ素 ,  細胞毒性 ,  セレン ,  改善効果