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J-GLOBAL ID：201802213998529554   Reference number：18A0271470

The Induction of Selected Wnt Target Genes by Tcf1 Mediates Generation of Tumorigenic Colon Stem Cells

腫瘍原性結腸幹細胞のTcf1を仲介する発生による選択されたWnt標的遺伝子の誘導【Powered by NICT】

Author (10)： Shiokawa Daisuke (Division of Cancer Differentiation, National Cancer Center Research Institute, Chuo-ku, Tokyo 104-0045, Japan) ,  Sato Ai (Division of Cancer Differentiation, National Cancer Center Research Institute, Chuo-ku, Tokyo 104-0045, Japan) ,  Ohata Hirokazu (Division of Cancer Differentiation, National Cancer Center Research Institute, Chuo-ku, Tokyo 104-0045, Japan) ,  Mutoh Michihiro (Division of Prevention Research, Research Center for Cancer Prevention and Screening, Chuo-ku, Tokyo 104-0045, Japan) ,  Sekine Shigeki (Department of Pathology, National Cancer Center Hospital, Chuo-ku, Tokyo 104-0045, Japan) ,  Kato Mamoru (Fundamental Innovative Oncology Core, National Cancer Center Research Institute, Chuo-ku, Tokyo 104-0045, Japan) ,  Shibata Tatsuhiro (Division of Cancer Genomics, National Cancer Center Research Institute, Chuo-ku, Tokyo 104-0045, Japan) ,  Shibata Tatsuhiro (Laboratory of Molecular Medicine, The Institute of Medical Science, The University of Tokyo, Tokyo 108-0071, Japan) ,  Nakagama Hitoshi (Division of Carcinogenesis and Cancer Prevention, National Cancer Center Research Institute, Chuo-ku, Tokyo 104-0045, Japan) ,  Okamoto Koji (Division of Cancer Differentiation, National Cancer Center Research Institute, Chuo-ku, Tokyo 104-0045, Japan)
Material： Cell Reports
Volume： 19  Issue： 5  Page： 981-994  Publication year： 2017 
JST Material Number： W3124A  ISSN： 2211-1247  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： The generation of tumor-initia...

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Thesaurus term： *stem cell ,  subset ,  *carcinogenicity ,  tumorigenesis ,  *tumor ,  quantitative polymerase chain reaction ,  *colon ,  colonic neoplasm
Semi thesaurus term： βカテニン ,  遺伝子発現プロファイリング ,  *腸幹細胞 ,  Lgr5 ,  結腸発癌 ,  *標的遺伝子 ,  *Wnt蛋白質 , 【Automatic Indexing@JST】

JST classification (2)： Cell physiology in general  (EF02010S) ,  Biological function  (EB03040U)

Terms in the title (8)： 腫瘍原性 ,  結腸 ,  幹細胞 ,  TCF1 ,  仲介 ,  Wnt ,  標的遺伝子 ,  誘導