Art

J-GLOBAL ID：201802214461468769   Reference number：18A1365139

Notch1 regulates invasion and metastasis of head and neck squamous cell carcinoma by inducing EMT through c-Myc

Notch1は,c-Mycを介してEMTを誘導することにより頭頸部扁平上皮癌の浸潤および転移を調節する

Author (10)： Inamura Naoya (Department of Otolaryngology-Head and Neck Surgery, Hokkaido University Graduate School of Medicine, N15W7, Kita-ku, Sapporo 060-8638, Japan) ,  Kimura Taichi (Department of Translational Pathology, Hokkaido University Graduate School of Medicine, N15W7, Kita-ku, Sapporo 060-8638, Japan) ,  Wang Lei (Department of Translational Pathology, Hokkaido University Graduate School of Medicine, N15W7, Kita-ku, Sapporo 060-8638, Japan) ,  Yanagi Hiroko (Department of Otolaryngology-Head and Neck Surgery, Hokkaido University Graduate School of Medicine, N15W7, Kita-ku, Sapporo 060-8638, Japan) ,  Tsuda Masumi (Department of Cancer Pathology, Hokkaido University Graduate School of Medicine, N15W7, Kita-ku, Sapporo 060-8638, Japan) ,  Tanino Mishie (Department of Cancer Pathology, Hokkaido University Graduate School of Medicine, N15W7, Kita-ku, Sapporo 060-8638, Japan) ,  Nishihara Hiroshi (Department of Translational Pathology, Hokkaido University Graduate School of Medicine, N15W7, Kita-ku, Sapporo 060-8638, Japan) ,  Fukuda Satoshi (Department of Otolaryngology-Head and Neck Surgery, Hokkaido University Graduate School of Medicine, N15W7, Kita-ku, Sapporo 060-8638, Japan) ,  Tanaka Shinya (Department of Translational Pathology, Hokkaido University Graduate School of Medicine, N15W7, Kita-ku, Sapporo 060-8638, Japan) ,  Tanaka Shinya (Department of Cancer Pathology, Hokkaido University Graduate School of Medicine, N15W7, Kita-ku, Sapporo 060-8638, Japan)
Material： Auris Nasus Larynx  (International Journal of ORL & HNS)
Volume： 44  Issue： 4  Page： 447-457  Publication year： Aug. 2017 
JST Material Number： W2247A  ISSN： 0385-8146  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： c-Myc ,...

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Author keywords (5)： Notch1 ,  Head and neck cancer ,  Squamous cell carcinoma ,  Growth ,  Invasion

JST classification (3)： Basic oncology in general  (GE02010R) ,  Biological function  (EB03040U) ,  Tumors(=neoplasms)of tooth and mouth(=oral cavity)  (GT04000N)

Substance index (1)： DAPT

Terms in the title (7)： Notch1 ,  c-Myc ,  EMT ,  誘導 ,  頭頸部扁平上皮癌 ,  浸潤 ,  調節