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J-GLOBAL ID：201802214878688046   Reference number：18A0403968

Ceritinib versus chemotherapy in patients with ALK-rearranged non-small-cell lung cancer previously given chemotherapy and crizotinib (ASCEND-5): a randomised, controlled, open-label, phase 3 trial

以前化学療法とクリゾチニブ(ASCEND 5)を与えられたALK再配列非小細胞肺癌患者におけるCeritinibと化学療法:無作為化,対照,非盲検,第3相試験【Powered by NICT】

Author (21)： Shaw Alice T (Massachusetts General Hospital, Boston, MA, USA) ,  Kim Tae Min (Seoul National University Hospital, Seoul, Korea) ,  Crino Lucio (Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori, Istituto di Ricovero e Cura a Carattere Scientifico, Meldola, Italy) ,  Gridelli Cesare (SG Moscati Hospital, Citta Ospedaliera, Contrada Amoretta, Avellino, Italy) ,  Kiura Katsuyuki (Okayama University Hospital, Okayama, Japan) ,  Liu Geoffrey (Princess Margaret Cancer Centre, Toronto, ON, Canada) ,  Novello Silvia (University of Torino, Torino, Italy) ,  Bearz Alessandra (Istituto di Ricovero e Cura a Carattere Scientifico-Centro di Riferimento Oncologico, Aviano, Italy) ,  Gautschi Oliver (Cantonal Hospital Lucerne, Lucerne, Switzerland) ,  Mok Tony (State Key Laboratory of South China, Chinese University of Hong Kong, Shatin, China) ,  Nishio Makoto (Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, Japan) ,  Scagliotti Giorgio (University of Torino, Torino, Italy) ,  Spigel David R (Sarah Cannon Research Institute, Nashville, TN, USA) ,  Deudon Stephanie (Novartis, Basel, Switzerland) ,  Zheng Cheng (Novartis, East Hanover, NJ, USA) ,  Pantano Serafino (Novartis, Basel, Switzerland) ,  Urban Patrick (Novartis, Basel, Switzerland) ,  Massacesi Cristian (Novartis, Basel, Switzerland) ,  Viraswami-Appanna Kalyanee (Novartis, East Hanover, NJ, USA) ,  Felip Enriqueta (Vall d’Hebron University Hospital, Barcelona, Spain) ,  Felip Enriqueta (Vall d’Hebron Institute of Oncology, Barcelona, Spain)
Material： Lancet Oncology  (Lancet Oncol)
Volume： 18  Issue： 7  Page： 874-886  Publication year： 2017 
JST Material Number： W1266A  ISSN： 1470-2045  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Ceritinib is a next-generation...

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Thesaurus term： evaluation criterion ,  toxicity ,  Safety ,  pretreatment ,  *patient ,  *drug therapy ,  *phase 3 study ,  *non-small cell lung cancer ,  alanine aminotransferase ,  Platinum ,  intravenous administration ,  robustness ,  adverse reaction
Semi thesaurus term： 有害事象 ,  癌治療 ,  阻害剤 , 【Automatic Indexing@JST】

JST classification (1)： Treatment for tumors in general  (GE03031L)

Terms in the title (9)： 化学療法 ,  クリゾチニブ ,  ALK ,  再配列 ,  非小細胞肺癌 ,  患者 ,  対照 ,  盲 ,  第3相試験