Art

J-GLOBAL ID：201802214956066293   Reference number：18A0180227

Inhibitory role of Munc13-1 in antigen-induced mast cell degranulation

抗原誘発性肥満細胞の脱顆粒におけるMunc13-1の阻害的役割

Author (4)： HIGASHIO Hironori (Department of Chemistry, Center for Liberal Arts and Sciences, Iwate Medical University) ,  SATOH Yoh-ichi (Department of Anatomy (Cell Biology), Iwate Medical University) ,  SATOH Yoh-ichi (Department of Medical Education, Iwate Medical University) ,  SAINO Tomoyuki (Department of Anatomy (Cell Biology), Iwate Medical University)
Material： Biomedical Research (Web)
Volume： 38  Issue： 6  Page： 321-329(J-STAGE)  Publication year： 2017 
JST Material Number： U1102A  ISSN： 1880-313X  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *mastocyte ,...
Semi thesaurus term： Fc epsilon RI ,...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=18A0180227&from=J-GLOBAL&jstjournalNo=U1102A") }}

JST classification (2)： Immunological reaction in general  (ED03010T) ,  Biological function  (EB03040U)

Reference (38)：

• 1 Abraham SN and St John AL (2010) Mast cell-orchestrated immunity to pathogens. Nat Rev Immunol 10, 440-452.
• 2 Augustin I, Rosenmund C, Südhof TC and Brose N (1999) Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles. Nature 400, 457-461.
• 3 Augustin I, Korte S, Rickmann M, Kretzschmar HA, Südhof TC, Herms JW and Brose N (2001) The cerebellum-specific Munc13 isoform Munc13-3 regulates cerebellar synaptic transmission and motor learning in mice. J Neurosci 21, 10-17.
• 4 Azouz NP, Zur N, Efergan A, Ohbayashi N, Fukuda M, Amihai D, Hammel I, Rothenberg ME and Sagi-Eisenberg R (2014) Rab5 is a novel regulator of mast cell secretory granules: impact on size, cargo, and exocytosis. J Immunol 192, 4043-4053.
• 5 Baram D, Adachi R, Medalia O, Tuvim M, Dickey BF, Mekori YA and Sagi-Eisenberg R (1999) Synaptotagmin II negatively regulates Ca²⁺-triggered exocytosis of lysosomes in mast cells. J Exp Med 189, 1649-1658.

Terms in the title (5)： 抗原 ,  肥満細胞 ,  脱顆粒 ,  阻害 ,  役割