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J-GLOBAL ID：201802215482230279   Reference number：18A0948228

エビデンスと機序から尿酸コントロールによる血圧と腎機能への好影響を考える

Author (1)： HISATOME ICHIRO (鳥取大 大学院医学系研究科 機能医科学専攻 遺伝子再生医療学 再生医療学)
Material： 日本臨床生理学会雑誌  (Journal of Clinical Physiology)
Volume： 48  Issue： 2  Page： 67-72  Publication year： May. 01, 2018 
JST Material Number： Y0689A  ISSN： 0286-7052  Document type： Article
Article type： 解説  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： human(primates) ,...
Semi thesaurus term： mechanism of pathogenesis ,...

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JST classification (3)： Metabolic diseases,nutritional diseases in general.  (GD05010J) ,  Cardiovascular system diseases  (GJ03000C) ,  Urogenital diseases  (GM03000L)

Substance index (1)： Allopurinol

Reference (22)：

• Kuwabara M, Niwa K, Nishi Y, Mizuno A, Asano T, Masuda K, Komatsu I, Yamazoe M, Takahashi O, Hisatome I: Relationship between serum uric acid levels and hypertension among Japanese individuals not treated for hyperuricemia and hypertension. Hypertens Res 2014, 37(8): 785-789
• Kuwabara M, Niwa K, Hisatome I, Nakagawa T, Roncal-Jimenez CA, Andres-Hernando A, Bjornstad P, Jensen T, Sato Y, Milagres T, Garcia G, Ohno M, Lanaspa MA, Johnson RJ: Asymptomatic hyperuricemia without comorbidities predicts cardiometabolic diseases: Five-year Japanese cohort study. Hypertension 2017, 69(6): 1036-1044
• Grayson PC, Kim SY, LaValley M, Choi HK: Hyperuricemia and incident hypertension: a systematic review and meta-analysis. Arthritis Care Res (Hoboken) 2011, 63(1): 102-110
• Spiekermann S, Landmesser U, Dikalov S, Bredt M, Gamez G, Tatge H, Reepschläger N, Hornig B, Drexler H, Harrison DG: Electron spin resonance characterization of vascular xanthine and NAD(P)H oxidase activity in patients with coronary artery disease: relation to endothelium-dependent vasodilation. Circulation 2003, 107(10): 1383-1389
• Mishima M, Hamada T, Maharani N, Ikeda N, Onohara T, Notsu T, Ninomiya H, Miyazaki S, Mizuta E, Sugihara S, Kato M, Ogino K, Kuwabara M, Hirota Y, Yoshida A, Otani N, Anzai N, Hisatome I: Effects of uric acid on the NO production of HUVECs and its restoration by urate lowering agents. Drug Res (Stuttg) 2016, 66(5): 270-274.

Terms in the title (5)： エビデンス ,  尿酸 ,  コントロール ,  血圧 ,  腎機能